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PMID: 8143347 Published · ppublish English Journal Article Review

Focal adhesion as a signal transduction organelle.

Cancer metastasis reviews ·Vol. 13 ·No. 1 ·1994-03-00 ·Pages 9-24

Lo SH, Chen LB

Abstract

暂无摘要

MeSH Terms
Actins/metabolism Animals Cell Adhesion Cell Adhesion Molecules/physiology Cell Membrane/physiology Cell Transformation, Neoplastic Humans Microfilament Proteins/metabolism Organelles/physiology Recombinant Proteins/metabolism Signal Transduction Tensins
Chemicals
Actins Cell Adhesion Molecules Microfilament Proteins Recombinant Proteins Tensins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Lo S H
Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
Chen L B
References (136)
136 references, click to expand
  1. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors.
    Cell. 1992 Aug 7;70(3):389-99 PMID: 1643657
  2. Adhesions of fibroblasts to substratum during contact inhibition observed by interference reflection microscopy.
    Exp Cell Res. 1975 Apr;92(1):57-62 PMID: 1169157
  3. The noncatalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine-phosphorylated cellular proteins with high affinity.
    Proc Natl Acad Sci U S A. 1991 Jan 15;88(2):627-31 PMID: 1703304
  4. A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells.
    J Cell Biol. 1984 Sep;99(3):1045-59 PMID: 6206076
  5. Vinculin, a cytoskeletal substrate of protein kinase C.
    J Biol Chem. 1983 Oct 10;258(19):11423-6 PMID: 6225775
  6. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role.
    Cell. 1991 Jul 12;66(1):107-19 PMID: 2070412
  7. Elevated levels of the alpha 5 beta 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells.
    Cell. 1990 Mar 9;60(5):849-59 PMID: 2155708
  8. Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors.
    Science. 1990 Nov 16;250(4983):979-82 PMID: 2173144
  9. Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton.
    J Cell Biol. 1989 Jun;108(6):2401-8 PMID: 2472406
  10. Phosphorylation of talin at tyrosine in Rous sarcoma virus-transformed cells.
    Mol Cell Biol. 1987 Jan;7(1):371-8 PMID: 3031468
  11. Association of the erythropoietin receptor with protein tyrosine kinase activity.
    Proc Natl Acad Sci U S A. 1992 Jul 15;89(14):6237-41 PMID: 1378622
  12. Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK.
    Mol Cell Biol. 1993 Feb;13(2):785-91 PMID: 8423801
  13. The adhesion plaque protein, talin, is phosphorylated in vivo in chicken embryo fibroblasts exposed to a tumor-promoting phorbol ester.
    Cell Regul. 1990 Jan;1(2):227-36 PMID: 2129221
  14. A 25-kD inhibitor of actin polymerization is a low molecular mass heat shock protein.
    J Cell Biol. 1991 Jul;114(2):255-61 PMID: 2071672
  15. Properties of smooth muscle vinculin.
    J Biol Chem. 1984 Mar 25;259(6):3916-24 PMID: 6323447
  16. Activation of the proto-oncogene p60c-src by point mutations in the SH2 domain.
    Mol Cell Biol. 1990 Jun;10(6):2855-62 PMID: 2111444
  17. Identification of a filamin isoform enriched at the ends of stress fibers in chicken embryo fibroblasts.
    J Cell Sci. 1989 Sep;94 ( Pt 1):109-18 PMID: 2693470
  18. Cellular transformation, tyrosine kinase oncogenes, and the cellular adhesion plaque.
    Bioessays. 1988 Jan;8(1):25-30 PMID: 3130051
  19. Conformational states of fibronectin. Effects of pH, ionic strength, and collagen binding.
    J Biol Chem. 1982 Dec 25;257(24):14973-8 PMID: 7174679
  20. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling.
    Cell. 1992 Aug 7;70(3):401-10 PMID: 1643658
  21. Transmembrane molecular assemblies in cell-extracellular matrix interactions.
    Curr Opin Cell Biol. 1991 Oct;3(5):849-53 PMID: 1931085
  22. Talin anchors and nucleates actin filaments at lipid membranes. A direct demonstration.
    FEBS Lett. 1992 Dec 14;314(2):203-5 PMID: 1459252
  23. Modular organization of actin crosslinking proteins.
    Trends Biochem Sci. 1991 Mar;16(3):87-92 PMID: 2058002
  24. Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.
    J Cell Biol. 1992 Nov;119(4):893-903 PMID: 1385444
  25. Direct interactions between talin and actin.
    Biochem Biophys Res Commun. 1990 Sep 28;171(3):1217-23 PMID: 2121138
  26. Radixin, a barbed end-capping actin-modulating protein, is concentrated at the cleavage furrow during cytokinesis.
    J Cell Biol. 1991 Apr;113(2):321-30 PMID: 1707055
  27. Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I.
    Nature. 1990 Jan 18;343(6255):288-90 PMID: 2405279
  28. A 130K protein from chicken gizzard: its localization at the termini of microfilament bundles in cultured chicken cells.
    Cell. 1979 Sep;18(1):193-205 PMID: 574428
  29. A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites.
    J Cell Sci. 1992 Sep;103 ( Pt 1):131-43 PMID: 1429901
  30. The synapsins.
    Annu Rev Cell Biol. 1990;6:433-60 PMID: 1980418
  31. Multiple integrins share the ability to induce elevation of intracellular pH.
    Exp Cell Res. 1991 Aug;195(2):533-5 PMID: 1712734
  32. Expression of transformation-associated protease(s) that degrade fibronectin at cell contact sites.
    J Cell Biol. 1984 Apr;98(4):1546-55 PMID: 6325472
  33. Dependence of the shape of the plasma fibronectin molecule on solvent composition. Ionic strength and glycerol content.
    J Biol Chem. 1983 Dec 10;258(23):14545-9 PMID: 6643501
  34. Microinjection of gelsolin into living cells.
    J Cell Biol. 1987 Mar;104(3):491-501 PMID: 3029140
  35. Mechanism of the insertion of actin monomers between the barbed ends of actin filaments and barbed end-bound insertin.
    J Muscle Res Cell Motil. 1991 Feb;12(1):27-36 PMID: 2050808
  36. Membrane proteases: roles in tissue remodeling and tumour invasion.
    Curr Opin Cell Biol. 1992 Oct;4(5):802-9 PMID: 1419057
  37. Coupled expression and colocalization of 140K cell adhesion molecules, fibronectin, and laminin during morphogenesis and cytodifferentiation of chick lung cells.
    J Cell Biol. 1986 Sep;103(3):1073-90 PMID: 3528168
  38. Reconstitution of functional receptors for human granulocyte/macrophage colony-stimulating factor (GM-CSF): evidence that the protein encoded by the AIC2B cDNA is a subunit of the murine GM-CSF receptor.
    Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5082-6 PMID: 1828890
  39. Substrates for p34cdc2: in vivo veritas?
    Cell. 1990 May 18;61(4):549-51 PMID: 2188729
  40. Interaction of plasma membrane fibronectin receptor with talin--a transmembrane linkage.
    Nature. 1986 Apr 10-16;320(6062):531-3 PMID: 2938015
  41. pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.
    Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):5192-6 PMID: 1594631
  42. Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo.
    EMBO J. 1992 Apr;11(4):1373-82 PMID: 1314164
  43. Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation.
    Nature. 1992 Aug 20;358(6388):690-2 PMID: 1379699
  44. Presence of an SH2 domain in the actin-binding protein tensin.
    Science. 1991 May 3;252(5006):712-5 PMID: 1708917
  45. Zyxin and cCRP: two interactive LIM domain proteins associated with the cytoskeleton.
    J Cell Biol. 1992 Dec;119(6):1573-87 PMID: 1469049
  46. Association of type 3 protein kinase C with focal contacts in rat embryo fibroblasts.
    J Cell Biol. 1989 Aug;109(2):697-704 PMID: 2668303
  47. Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor.
    J Cell Biol. 1989 Mar;108(3):921-30 PMID: 2646308
  48. Actin-binding proteins.
    Curr Opin Cell Biol. 1991 Feb;3(1):87-97 PMID: 1854489
  49. Protein modification: phosphorylation on tyrosine residues.
    Curr Opin Cell Biol. 1989 Dec;1(6):1168-81 PMID: 2561455
  50. Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association.
    Science. 1991 Jun 14;252(5012):1523-8 PMID: 2047859
  51. Molecular structure of F-actin and location of surface binding sites.
    Nature. 1990 Nov 15;348(6298):217-21 PMID: 2234090
  52. Disruption of microfilament organization after injection of F-actin capping proteins into living tissue culture cells.
    Nature. 1983 Jul 28-Aug 3;304(5924):361-4 PMID: 6683786
  53. Identification of a transformation-specific antigen induced by an avian sarcoma virus.
    Nature. 1977 Sep 22;269(5626):346-8 PMID: 198667
  54. The 102 kd cadherin-associated protein: similarity to vinculin and posttranscriptional regulation of expression.
    Cell. 1991 May 31;65(5):849-57 PMID: 1904011
  55. Suppression of tumorigenicity in transformed cells after transfection with vinculin cDNA.
    J Cell Biol. 1992 Oct;119(2):427-38 PMID: 1400584
  56. Tetrahymena actin: copolymerization with skeletal muscle actin and interactions with muscle actin-binding proteins.
    J Biochem. 1990 Jan;107(1):32-6 PMID: 2110155
  57. Alpha-actinin: immunofluorescent localization of a muscle structural protein in nonmuscle cells.
    Cell. 1975 Nov;6(3):289-98 PMID: 802682
  58. Transformation parameters and pp60src localization in cells infected with partial transformation mutants of Rous sarcoma virus.
    Mol Cell Biol. 1983 Apr;3(4):731-46 PMID: 6190075
  59. Purification and characterization of zyxin, an 82,000-dalton component of adherens junctions.
    J Biol Chem. 1991 Mar 25;266(9):5847-53 PMID: 2005121
  60. Tumor promoters and the mechanism of tumor promotion.
    Adv Cancer Res. 1980;32:1-74 PMID: 7008542
  61. Proteins with SH2 domains: transducers in the tyrosine kinase signaling pathway.
    Cell Growth Differ. 1992 Jan;3(1):73-80 PMID: 1534689
  62. Erythropoietin receptor and interleukin-2 receptor beta chain: a new receptor family.
    Cell. 1989 Sep 22;58(6):1023-4 PMID: 2550142
  63. Phosphotyrosine-containing proteins are concentrated in focal adhesions and intercellular junctions in normal cells.
    Proc Natl Acad Sci U S A. 1985 Oct;82(19):6576-80 PMID: 2413441
  64. Mobility of microinjected rhodamine actin within living chicken gizzard cells determined by fluorescence photobleaching recovery.
    Cell. 1982 Jul;29(3):835-45 PMID: 6891291
  65. Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors.
    Cell. 1991 Sep 20;66(6):1165-74 PMID: 1833064
  66. Atomic model of the actin filament.
    Nature. 1990 Sep 6;347(6288):44-9 PMID: 2395461
  67. Dystrophin as a focal adhesion protein. Collocalization with talin and the Mr 48,000 sarcolemmal protein in cultured Xenopus muscle.
    FEBS Lett. 1990 Nov 12;274(1-2):171-4 PMID: 2123804
  68. Ca2+-activated, phospholipid-dependent protein kinase catalyzes the phosphorylation of actin-binding proteins.
    Biochem Biophys Res Commun. 1984 Feb 14;118(3):736-42 PMID: 6231024
  69. A role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis.
    J Cell Biol. 1991 Oct;115(2):517-33 PMID: 1918152
  70. The actin cytoskeleton.
    Electron Microsc Rev. 1988;1(1):155-74 PMID: 2485000
  71. SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins.
    Science. 1991 May 3;252(5006):668-74 PMID: 1708916
  72. Structure and mobility of actin filaments as measured by quasielastic light scattering, viscometry, and electron microscopy.
    J Biol Chem. 1986 Jun 25;261(18):8357-62 PMID: 3013849
  73. Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctate structures in macrophage filopodia.
    J Exp Med. 1990 Oct 1;172(4):1211-5 PMID: 2212950
  74. Paxillin is a major phosphotyrosine-containing protein during embryonic development.
    J Cell Biol. 1991 Oct;115(1):201-7 PMID: 1717477
  75. A rapid purification of alpha-actinin, filamin, and a 130,000-dalton protein from smooth muscle.
    J Biol Chem. 1980 Feb 10;255 (3):1194-9 PMID: 7356657
  76. Association of the v-crk oncogene product with phosphotyrosine-containing proteins and protein kinase activity.
    Proc Natl Acad Sci U S A. 1990 Apr;87(7):2638-42 PMID: 1690891
  77. Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.
    Proc Natl Acad Sci U S A. 1990 May;87(9):3328-32 PMID: 2110361
  78. Turnover of inositol phospholipids and signal transduction.
    Science. 1984 Sep 21;225(4668):1365-70 PMID: 6147898
  79. Effects of cytochalasin and phalloidin on actin.
    J Cell Biol. 1987 Oct;105(4):1473-8 PMID: 3312229
  80. The role of phosphorylation and limited proteolytic cleavage of talin and vinculin in the disruption of focal adhesion integrity.
    J Biol Chem. 1989 Jul 15;264(20):11938-44 PMID: 2545690
  81. A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps.
    Mol Cell Biol. 1986 Dec;6(12):4396-408 PMID: 3025655
  82. Phosphorylation of the fibronectin receptor complex in cells transformed by oncogenes that encode tyrosine kinases.
    Proc Natl Acad Sci U S A. 1986 Sep;83(17):6470-4 PMID: 3018734
  83. Cytoplasmic pH and anchorage-independent growth induced by v-Ki-ras, v-src or polyoma middle T.
    Oncogene. 1990 Jan;5(1):55-8 PMID: 2181378
  84. Adhesion plaques of Rous sarcoma virus-transformed cells contain the src gene product.
    Proc Natl Acad Sci U S A. 1980 Jun;77(6):3514-8 PMID: 6251464
  85. Effect of cell spreading on cytoplasmic pH in normal and transformed fibroblasts.
    Proc Natl Acad Sci U S A. 1989 Jun;86(12):4525-9 PMID: 2734302
  86. A conserved domain regulates interactions of the v-fps protein-tyrosine kinase with the host cell.
    Proc Natl Acad Sci U S A. 1987 Dec;84(24):9064-8 PMID: 3480531
  87. Linker insertion-deletion mutagenesis of the v-src gene: isolation of host- and temperature-dependent mutants.
    J Virol. 1989 Feb;63(2):542-54 PMID: 2536090
  88. Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src.
    Mol Cell Biol. 1990 Apr;10(4):1307-18 PMID: 2108315
  89. Focal adhesion sites and the removal of substratum-bound fibronectin.
    J Cell Biol. 1986 Dec;103(6 Pt 2):2697-706 PMID: 2947902
  90. Reorganization of actin filament bundles in living fibroblasts.
    J Cell Biol. 1984 Oct;99(4 Pt 1):1478-85 PMID: 6541223
  91. Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton.
    Annu Rev Cell Biol. 1988;4:487-525 PMID: 3058164
  92. SH2 domains recognize specific phosphopeptide sequences.
    Cell. 1993 Mar 12;72(5):767-78 PMID: 7680959
  93. Vinculin: a cytoskeletal target of the transforming protein of Rous sarcoma virus.
    Cell. 1981 Apr;24(1):165-74 PMID: 6263485
  94. Effect of villin on the kinetics of actin polymerization.
    Biochemistry. 1984 Jun 5;23(12):2613-21 PMID: 6432033
  95. Compare and contrast actin filaments and microtubules.
    Mol Biol Cell. 1992 Dec;3(12):1309-15 PMID: 1493331
  96. A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor.
    Cell. 1993 Mar 12;72(5):791-800 PMID: 8453669
  97. Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways.
    Cell. 1992 May 1;69(3):413-23 PMID: 1374684
  98. Characterization of an inhibitor of actin polymerization in vinculin-rich fraction of turkey gizzard smooth muscle.
    Eur J Biochem. 1988 Dec 15;178(2):543-53 PMID: 3145203
  99. Talin is phosphorylated on tyrosine in chicken embryo fibroblasts transformed by Rous sarcoma virus.
    Proc Natl Acad Sci U S A. 1986 Aug;83(15):5507-11 PMID: 2426700
  100. Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins.
    Mol Cell Biol. 1991 Mar;11(3):1607-13 PMID: 1705010
  101. Cytoskeleton--plasma membrane interactions.
    Science. 1992 Nov 6;258(5084):955-64 PMID: 1439807
  102. A re-examination of the interaction of vinculin with actin.
    J Cell Biol. 1986 Mar;102(3):1085-92 PMID: 3005334
  103. Platelet-derived growth factor-induced alterations in vinculin and actin distribution in BALB/c-3T3 cells.
    J Cell Biol. 1985 Apr;100(4):1031-40 PMID: 3920222
  104. Interaction of tumour promoters with epithelial cells in culture. An immunofluorescence study.
    Exp Cell Res. 1985 Oct;160(2):259-74 PMID: 3930274
  105. Fluorimetry study of N-(1-pyrenyl)iodoacetamide-labelled F-actin. Local structural change of actin protomer both on polymerization and on binding of heavy meromyosin.
    Eur J Biochem. 1981;114(1):33-8 PMID: 7011802
  106. Universal control mechanism regulating onset of M-phase.
    Nature. 1990 Apr 5;344(6266):503-8 PMID: 2138713
  107. SH2 and SH3 domains: from structure to function.
    Cell. 1992 Oct 30;71(3):359-62 PMID: 1423600
  108. The 46/50 kDa phosphoprotein VASP purified from human platelets is a novel protein associated with actin filaments and focal contacts.
    EMBO J. 1992 Jun;11(6):2063-70 PMID: 1318192
  109. Suppression of tumorigenicity in simian virus 40-transformed 3T3 cells transfected with alpha-actinin cDNA.
    Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):383-7 PMID: 8380636
  110. Atomic structure of the actin:DNase I complex.
    Nature. 1990 Sep 6;347(6288):37-44 PMID: 2395459
  111. Reorganization of alpha-actinin and vinculin induced by a phorbol ester in living cells.
    J Cell Biol. 1986 Apr;102(4):1430-8 PMID: 3082892
  112. Evidence that a 27-residue sequence is the actin-binding site of ABP-120.
    J Biol Chem. 1991 Jul 15;266(20):12989-93 PMID: 2071586
  113. Cellular contractility and the visible effects of cytochalasin.
    Front Biol. 1978;46:277-429 PMID: 352744
  114. Talin binds to actin and promotes filament nucleation.
    FEBS Lett. 1991 Jun 24;284(2):187-91 PMID: 1905648
  115. MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin.
    Nature. 1992 Apr 16;356(6370):618-22 PMID: 1560845
  116. Protein kinase C involvement in focal adhesion formation.
    J Cell Sci. 1992 Feb;101 ( Pt 2):277-90 PMID: 1629245
  117. Integrins: versatility, modulation, and signaling in cell adhesion.
    Cell. 1992 Apr 3;69(1):11-25 PMID: 1555235
  118. An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.
    J Cell Biol. 1990 Aug;111(2):721-9 PMID: 2116421
  119. A new 400-kD protein from isolated adherens junctions: its localization at the undercoat of adherens junctions and at microfilament bundles such as stress fibers and circumferential bundles.
    J Cell Biol. 1989 Dec;109(6 Pt 1):2905-15 PMID: 2687289
  120. The locomotion of fibroblasts in culture. IV. Electron microscopy of the leading lamella.
    Exp Cell Res. 1971 Aug;67(2):359-67 PMID: 5097522
  121. An interaction between vinculin and talin.
    Nature. 1984 Apr 19-25;308(5961):744-6 PMID: 6425696
  122. Purification and characterization of a protein from chicken gizzard, which inhibits actin polymerization.
    Eur J Biochem. 1985 Dec 16;153(3):515-20 PMID: 4076188
  123. Identification of a short sequence essential for actin binding by Dictyostelium ABP-120.
    J Biol Chem. 1990 Jun 5;265(16):9236-40 PMID: 2345173
  124. The dynamics of cytoskeletal organization in areas of cell contact.
    Cell Muscle Motil. 1984;5:195-234 PMID: 6423268
  125. BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner.
    Cell. 1991 Jul 12;66(1):161-71 PMID: 1712671
  126. Paxillin: a new vinculin-binding protein present in focal adhesions.
    J Cell Biol. 1990 Sep;111(3):1059-68 PMID: 2118142
  127. A new protein of adhesion plaques and ruffling membranes.
    J Cell Biol. 1983 Aug;97(2):359-67 PMID: 6684120
  128. The molecular basis for the assembly and modulation of adherens-type junctions.
    Cell Differ Dev. 1990 Dec 2;32(3):343-53 PMID: 2129157
  129. Deletions within the amino-terminal half of the c-src gene product that alter the functional activity of the protein.
    Mol Cell Biol. 1989 Mar;9(3):1109-19 PMID: 2471059
  130. Kinetic evidence for insertion of actin monomers between the barbed ends of actin filaments and barbed end-bound insertin, a protein purified from smooth muscle.
    J Mol Biol. 1989 Nov 5;210(1):141-8 PMID: 2555521
  131. Epidermal growth factor induces redistribution of actin and alpha-actinin in human epidermal carcinoma cells.
    Exp Cell Res. 1981 Aug;134(2):273-9 PMID: 6974095
  132. Deletions and insertions within an amino-terminal domain of pp60v-src inactivate transformation and modulate membrane stability.
    J Virol. 1989 Jan;63(1):291-302 PMID: 2535735
  133. E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells.
    J Cell Biol. 1991 Apr;113(1):173-85 PMID: 2007622
  134. Transforming gene product of Rous sarcoma virus phosphorylates tyrosine.
    Proc Natl Acad Sci U S A. 1980 Mar;77(3):1311-5 PMID: 6246487
  135. High-affinity interaction of vinculin with actin filaments in vitro.
    Cell. 1982 Jan;28(1):83-90 PMID: 6802502
  136. Occurrence of an actin-inserting domain in tensin.
    J Mol Biol. 1992 Sep 20;227(2):593-5 PMID: 1404377
Article Info
Journal
Cancer metastasis reviews
Abbr.
Cancer Metastasis Rev
ISSN
0167-7659
DOI
10.1007/BF00690415
Published
1994-03-00
Pages
9-24
Language
English
Region
Netherlands
NLM ID
8605731
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00690415 View journal details
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