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PMID: 18316045 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Translational control by cytoplasmic polyadenylation in Xenopus oocytes.

Biochimica et biophysica acta ·Vol. 1779 ·No. 4 ·2008-04-00 ·Pages 217-29

Radford HE, Meijer HA, de Moor CH

Abstract

Elongation of the poly(A) tails of specific mRNAs in the cytoplasm is a crucial regulatory step in oogenesis and early development of many animal species. The best studied example is the regulation of translation by cytoplasmic polyadenylation elements (CPEs) in the 3' untranslated region of mRNAs involved in Xenopus oocyte maturation. In this review we discuss the mechanism of translational control by the CPE binding protein (CPEB) in Xenopus oocytes as follows: 1. The cytoplasmic polyadenylation machinery such as CPEB, the subunits of cleavage and polyadenylation specificity factor (CPSF), symplekin, Gld-2 and poly(A) polymerase (PAP). 2. The signal transduction that leads to the activation of CPE-mediated polyadenylation during oocyte maturation, including the potential roles of kinases such as MAPK, Aurora A, CamKII, cdk1/Ringo and cdk1/cyclin B. 3. The role of deadenylation and translational repression, including the potential involvement of PARN, CCR4/NOT, maskin, pumilio, Xp54 (Ddx6, Rck), other P-body components and isoforms of the cap binding initiation factor eIF4E. Finally we discuss some of the remaining questions regarding the mechanisms of translational regulation by cytoplasmic polyadenylation and give our view on where our knowledge is likely to be expanded in the near future.

MeSH Terms
Animals Cytoplasm/metabolism Female Oocytes/cytology,metabolism Oogenesis/physiology Poly A/metabolism Polyadenylation/physiology Polynucleotide Adenylyltransferase/metabolism Protein Biosynthesis/physiology Protein Kinases/metabolism RNA-Binding Proteins/metabolism Signal Transduction/physiology Xenopus Xenopus Proteins/metabolism
Chemicals
RNA-Binding Proteins Xenopus Proteins Poly A Protein Kinases Polynucleotide Adenylyltransferase
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Radford Helois E
School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham, UK.
Meijer Hedda A
de Moor Cornelia H
References (153)
153 references, click to expand
  1. PUF protein-mediated deadenylation is catalyzed by Ccr4p.
    J Biol Chem. 2007 Jan 5;282(1):109-14 PMID: 17090538
  2. Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae.
    EMBO J. 2002 Mar 15;21(6):1427-36 PMID: 11889048
  3. Accumulation of polyadenylated mRNA, Pab1p, eIF4E, and eIF4G with P-bodies in Saccharomyces cerevisiae.
    Mol Biol Cell. 2007 Jul;18(7):2592-602 PMID: 17475768
  4. Meiotic maturation in Xenopus requires polyadenylation of multiple mRNAs.
    EMBO J. 1998 Jun 1;17(11):3168-75 PMID: 9606198
  5. The mechanism and regulation of deadenylation: identification and characterization of Xenopus PARN.
    RNA. 2001 Jun;7(6):875-86 PMID: 11424938
  6. The 30-kD subunit of mammalian cleavage and polyadenylation specificity factor and its yeast homolog are RNA-binding zinc finger proteins.
    Genes Dev. 1997 Jul 1;11(13):1703-16 PMID: 9224719
  7. Embryonic poly(A)-binding protein stimulates translation in germ cells.
    Mol Cell Biol. 2005 Mar;25(5):2060-71 PMID: 15713657
  8. A novel p34(cdc2)-binding and activating protein that is necessary and sufficient to trigger G(2)/M progression in Xenopus oocytes.
    Genes Dev. 1999 Aug 15;13(16):2177-89 PMID: 10465793
  9. Musashi regulates the temporal order of mRNA translation during Xenopus oocyte maturation.
    EMBO J. 2006 Jun 21;25(12):2792-801 PMID: 16763568
  10. Translational control by cytoplasmic polyadenylation during Xenopus oocyte maturation: characterization of cis and trans elements and regulation by cyclin/MPF.
    EMBO J. 1990 Nov;9(11):3743-51 PMID: 2145153
  11. General translational repression by activators of mRNA decapping.
    Cell. 2005 Sep 23;122(6):875-86 PMID: 16179257
  12. A novel embryonic poly(A) binding protein, ePAB, regulates mRNA deadenylation in Xenopus egg extracts.
    Genes Dev. 2001 Mar 15;15(6):774-88 PMID: 11274061
  13. Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.
    Nature. 2006 Dec 14;444(7121):953-6 PMID: 17128255
  14. Mouse cytoplasmic polyadenylylation element binding protein: an evolutionarily conserved protein that interacts with the cytoplasmic polyadenylylation elements of c-mos mRNA.
    Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14602-7 PMID: 8962099
  15. Translational control by cytoplasmic polyadenylation of c-mos mRNA is necessary for oocyte maturation in the mouse.
    EMBO J. 1994 Dec 1;13(23):5712-20 PMID: 7988567
  16. The 36-kilodalton embryonic-type cytoplasmic polyadenylation element-binding protein in Xenopus laevis is ElrA, a member of the ELAV family of RNA-binding proteins.
    Mol Cell Biol. 1997 Nov;17(11):6402-9 PMID: 9343402
  17. Progesterone and insulin stimulation of CPEB-dependent polyadenylation is regulated by Aurora A and glycogen synthase kinase-3.
    Genes Dev. 2004 Jan 1;18(1):48-61 PMID: 14724178
  18. The 3'-untranslated regions of c-mos and cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation.
    Genes Dev. 1994 Apr 15;8(8):926-38 PMID: 7926777
  19. CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapses.
    Neuron. 1998 Nov;21(5):1129-39 PMID: 9856468
  20. Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation.
    Mol Cell Biol. 2005 Dec;25(24):10930-9 PMID: 16314516
  21. EDEN and EDEN-BP, a cis element and an associated factor that mediate sequence-specific mRNA deadenylation in Xenopus embryos.
    EMBO J. 1998 Jan 2;17(1):278-87 PMID: 9427761
  22. Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation.
    Nat Cell Biol. 2006 Oct;8(10):1084-94 PMID: 16964245
  23. Regulation of the G(2)/M transition in Xenopus oocytes by the cAMP-dependent protein kinase.
    J Biol Chem. 2005 Jul 1;280(26):24339-46 PMID: 15860459
  24. Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice.
    Dev Cell. 2001 Aug;1(2):201-13 PMID: 11702780
  25. Function and regulation of Maskin, a TACC family protein, in microtubule growth during mitosis.
    J Cell Biol. 2005 Sep 26;170(7):1057-66 PMID: 16172207
  26. The Xenopus TACC homologue, maskin, functions in mitotic spindle assembly.
    Mol Biol Cell. 2005 Jun;16(6):2836-47 PMID: 15788567
  27. Biochemical identification of Xenopus Pumilio as a sequence-specific cyclin B1 mRNA-binding protein that physically interacts with a Nanos homolog, Xcat-2, and a cytoplasmic polyadenylation element-binding protein.
    J Biol Chem. 2001 Jun 15;276(24):20945-53 PMID: 11283000
  28. Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor.
    Mol Cell Biol. 1999 Nov;19(11):7733-40 PMID: 10523662
  29. Translational control by neuroguidin, a eukaryotic initiation factor 4E and CPEB binding protein.
    Mol Cell Biol. 2006 Jun;26(11):4277-87 PMID: 16705177
  30. The temporal control of Wee1 mRNA translation during Xenopus oocyte maturation is regulated by cytoplasmic polyadenylation elements within the 3'-untranslated region.
    Dev Biol. 2000 Nov 15;227(2):706-19 PMID: 11071785
  31. Complex protein interactions within the human polyadenylation machinery identify a novel component.
    Mol Cell Biol. 2000 Mar;20(5):1515-25 PMID: 10669729
  32. Site-directed ribose methylation identifies 2'-OH groups in polyadenylation substrates critical for AAUAAA recognition and poly(A) addition.
    Cell. 1991 Apr 5;65(1):125-33 PMID: 1901516
  33. Patterns of maternal messenger RNA accumulation and adenylation during oogenesis in Urechis caupo.
    Dev Biol. 1986 Sep;117(1):55-63 PMID: 3755690
  34. Regulation of calcium/calmodulin-dependent protein kinase II activation by intramolecular and intermolecular interactions.
    J Neurosci. 2004 Sep 29;24(39):8394-8 PMID: 15456810
  35. The Mos pathway regulates cytoplasmic polyadenylation in Xenopus oocytes.
    Mol Cell Biol. 1997 Nov;17(11):6419-26 PMID: 9343404
  36. Oocyte maturation: the coming of age of a germ cell.
    Semin Reprod Med. 2005 Aug;23(3):234-41 PMID: 16059829
  37. Symplekin and multiple other polyadenylation factors participate in 3'-end maturation of histone mRNAs.
    Genes Dev. 2005 Nov 1;19(21):2583-92 PMID: 16230528
  38. Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis.
    Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):14994-5001 PMID: 17008405
  39. Disruption of mouse poly(A) polymerase mGLD-2 does not alter polyadenylation status in oocytes and somatic cells.
    Biochem Biophys Res Commun. 2007 Dec 7;364(1):14-9 PMID: 17927953
  40. Hu proteins regulate polyadenylation by blocking sites containing U-rich sequences.
    J Biol Chem. 2007 Jan 26;282(4):2203-10 PMID: 17127772
  41. Poly(A) metabolism and polysomal recruitment of maternal mRNAs during early Xenopus development.
    Dev Biol. 1990 Jul;140(1):221-4 PMID: 2358121
  42. Rodent oocytes express an active adenylyl cyclase required for meiotic arrest.
    Dev Biol. 2003 Jun 15;258(2):385-96 PMID: 12798295
  43. Calcium elevation at fertilization coordinates phosphorylation of XErp1/Emi2 by Plx1 and CaMK II to release metaphase arrest by cytostatic factor.
    Curr Biol. 2005 Aug 23;15(16):1458-68 PMID: 16040245
  44. XGef is a CPEB-interacting protein involved in Xenopus oocyte maturation.
    Dev Biol. 2003 Mar 15;255(2):383-98 PMID: 12648498
  45. Translational control of maternal Cyclin B mRNA by Nanos in the Drosophila germline.
    Development. 2007 Apr;134(8):1519-27 PMID: 17360772
  46. A conserved role of a DEAD box helicase in mRNA masking.
    RNA. 2001 Dec;7(12):1728-42 PMID: 11780630
  47. CPEB: a life in translation.
    Trends Biochem Sci. 2007 Jun;32(6):279-85 PMID: 17481902
  48. Translational control by poly(A) elongation during Xenopus development: differential repression and enhancement by a novel cytoplasmic polyadenylation element.
    Genes Dev. 1992 Dec;6(12B):2580-91 PMID: 1285126
  49. Phosphorylation of maskin by Aurora-A participates in the control of sequential protein synthesis during Xenopus laevis oocyte maturation.
    J Biol Chem. 2005 Apr 8;280(14):13415-23 PMID: 15687499
  50. Nuclear polyadenylation factors recognize cytoplasmic polyadenylation elements.
    Genes Dev. 1994 May 1;8(9):1106-16 PMID: 7926790
  51. CPEB controls the cytoplasmic polyadenylation of cyclin, Cdk2 and c-mos mRNAs and is necessary for oocyte maturation in Xenopus.
    EMBO J. 1996 May 15;15(10):2582-92 PMID: 8665866
  52. Widespread use of poly(A) tail length control to accentuate expression of the yeast transcriptome.
    RNA. 2007 Jul;13(7):982-97 PMID: 17586758
  53. Cytoplasmic poly(A) polymerases mediate cellular responses to S phase arrest.
    Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12079-84 PMID: 12218190
  54. Specificity of RNA binding by CPEB: requirement for RNA recognition motifs and a novel zinc finger.
    Mol Cell Biol. 1998 Feb;18(2):685-93 PMID: 9447964
  55. Identification of a C-rich element as a novel cytoplasmic polyadenylation element in Xenopus embryos.
    Mech Dev. 2000 May;93(1-2):117-25 PMID: 10781945
  56. P bodies and the control of mRNA translation and degradation.
    Mol Cell. 2007 Mar 9;25(5):635-46 PMID: 17349952
  57. Translational control of maskin mRNA by its 3' untranslated region.
    Biol Cell. 2007 May;99(5):239-50 PMID: 17241108
  58. Symplekin, a novel type of tight junction plaque protein.
    J Cell Biol. 1996 Aug;134(4):1003-18 PMID: 8769423
  59. Identification of RNA-binding proteins specific to Xenopus Eg maternal mRNAs: association with the portion of Eg2 mRNA that promotes deadenylation in embryos.
    Development. 1992 Dec;116(4):1193-202 PMID: 1295736
  60. Cytoplasmic CstF-77 protein belongs to a masking complex with cytoplasmic polyadenylation element-binding protein in Xenopus oocytes.
    J Biol Chem. 2006 Sep 29;281(39):28687-98 PMID: 16882666
  61. Differential phosphorylation controls Maskin association with eukaryotic translation initiation factor 4E and localization on the mitotic apparatus.
    Mol Cell Biol. 2005 Sep;25(17):7605-15 PMID: 16107707
  62. 3'-End processing of pre-mRNA in eukaryotes.
    FEMS Microbiol Rev. 1999 Jun;23(3):277-95 PMID: 10371034
  63. A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor.
    EMBO J. 1997 Aug 1;16(15):4727-37 PMID: 9303317
  64. Symplekin and xGLD-2 are required for CPEB-mediated cytoplasmic polyadenylation.
    Cell. 2004 Nov 24;119(5):641-51 PMID: 15550246
  65. CPEB is a specificity factor that mediates cytoplasmic polyadenylation during Xenopus oocyte maturation.
    Cell. 1994 Nov 18;79(4):617-27 PMID: 7954828
  66. Speedy: a novel cell cycle regulator of the G2/M transition.
    EMBO J. 1999 Apr 1;18(7):1869-77 PMID: 10202150
  67. CDK1 and calcineurin regulate Maskin association with eIF4E and translational control of cell cycle progression.
    Nat Struct Mol Biol. 2006 Dec;13(12):1128-34 PMID: 17086181
  68. RINGO/cdk1 and CPEB mediate poly(A) tail stabilization and translational regulation by ePAB.
    Genes Dev. 2007 Oct 15;21(20):2571-9 PMID: 17938241
  69. Function of RNA-binding protein Musashi-1 in stem cells.
    Exp Cell Res. 2005 Jun 10;306(2):349-56 PMID: 15925591
  70. CPEB degradation during Xenopus oocyte maturation requires a PEST domain and the 26S proteasome.
    Dev Biol. 2001 Mar 15;231(2):447-58 PMID: 11237472
  71. Expression of a histone H1-like protein is restricted to early Xenopus development.
    Genes Dev. 1988 Oct;2(10):1284-95 PMID: 3060404
  72. Progesterone regulates the accumulation and the activation of Eg2 kinase in Xenopus oocytes.
    J Cell Sci. 2000 Apr;113 ( Pt 7):1127-38 PMID: 10704364
  73. Opposing polymerase-deadenylase activities regulate cytoplasmic polyadenylation.
    Mol Cell. 2006 Oct 20;24(2):173-83 PMID: 17052452
  74. Polyadenylation of maternal mRNA during oocyte maturation: poly(A) addition in vitro requires a regulated RNA binding activity and a poly(A) polymerase.
    EMBO J. 1992 Dec;11(13):5021-32 PMID: 1464324
  75. Polyadenylation: a tail of two complexes.
    Curr Biol. 2002 Dec 23;12(24):R855-7 PMID: 12498707
  76. Identification of post-transcriptionally regulated Xenopus tropicalis maternal mRNAs by microarray.
    Nucleic Acids Res. 2006 Feb 07;34(3):986-95 PMID: 16464828
  77. Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA.
    Nature. 2000 Mar 16;404(6775):302-7 PMID: 10749216
  78. Phosphorylation of CPEB by Eg2 mediates the recruitment of CPSF into an active cytoplasmic polyadenylation complex.
    Mol Cell. 2000 Nov;6(5):1253-9 PMID: 11106762
  79. Poly(A) elongation during Xenopus oocyte maturation is required for translational recruitment and is mediated by a short sequence element.
    Genes Dev. 1989 Jun;3(6):803-15 PMID: 2568313
  80. mRNA regulation by Puf domain proteins.
    Sci STKE. 2006 Sep 26;2006(354):pe37 PMID: 17003467
  81. Dissolution of the maskin-eIF4E complex by cytoplasmic polyadenylation and poly(A)-binding protein controls cyclin B1 mRNA translation and oocyte maturation.
    EMBO J. 2002 Jul 15;21(14):3852-62 PMID: 12110596
  82. Cytoplasmic polyadenylation element binding protein-dependent protein synthesis is regulated by calcium/calmodulin-dependent protein kinase II.
    J Neurosci. 2004 Jun 2;24(22):5193-201 PMID: 15175389
  83. Cytoplasmic polyadenylation elements mediate masking and unmasking of cyclin B1 mRNA.
    EMBO J. 1999 Apr 15;18(8):2294-303 PMID: 10205182
  84. Inhibition of mRNA deadenylation by the nuclear cap binding complex (CBC).
    J Biol Chem. 2006 Feb 17;281(7):4517-22 PMID: 16317009
  85. CPEB interacts with an ovary-specific eIF4E and 4E-T in early Xenopus oocytes.
    J Biol Chem. 2007 Dec 28;282(52):37389-401 PMID: 17942399
  86. Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules.
    J Cell Biol. 2005 Sep 26;170(7):1039-46 PMID: 16186253
  87. The polyadenylation factor CPSF-73 is involved in histone-pre-mRNA processing.
    Cell. 2005 Oct 7;123(1):37-48 PMID: 16213211
  88. Changes in the polyadenylation of specific stable RNA during the early development of Xenopus laevis.
    Gene. 1988 Dec 10;72(1-2):169-76 PMID: 2468559
  89. Evidence that multifunctional calcium/calmodulin-dependent protein kinase II (CaM KII) participates in the meiotic maturation of mouse oocytes.
    Mol Reprod Dev. 2002 Apr;61(4):560-9 PMID: 11891928
  90. RAP55, a cytoplasmic mRNP component, represses translation in Xenopus oocytes.
    J Biol Chem. 2006 Dec 29;281(52):40096-106 PMID: 17074753
  91. The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA.
    Mol Cell Biol. 2001 Jun;21(12):3888-900 PMID: 11359897
  92. MAPK interacts with XGef and is required for CPEB activation during meiosis in Xenopus oocytes.
    J Cell Sci. 2007 Mar 15;120(Pt 6):1093-103 PMID: 17344432
  93. Cdc2-cyclin B triggers H3 kinase activation of Aurora-A in Xenopus oocytes.
    J Biol Chem. 2003 Jun 13;278(24):21439-49 PMID: 12670933
  94. TACC3 is required for the proper mitosis of sclerotome mesenchymal cells during formation of the axial skeleton.
    Cancer Sci. 2007 Apr;98(4):555-62 PMID: 17359303
  95. Symplekin, a constitutive protein of karyo- and cytoplasmic particles involved in mRNA biogenesis in Xenopus laevis oocytes.
    Mol Biol Cell. 2002 May;13(5):1665-76 PMID: 12006661
  96. Involvement of Xenopus Pumilio in the translational regulation that is specific to cyclin B1 mRNA during oocyte maturation.
    Mech Dev. 2003 Aug;120(8):865-80 PMID: 12963108
  97. The active form of Xp54 RNA helicase in translational repression is an RNA-mediated oligomer.
    Nucleic Acids Res. 2004 Feb 24;32(4):1325-34 PMID: 14982957
  98. A PUF family portrait: 3'UTR regulation as a way of life.
    Trends Genet. 2002 Mar;18(3):150-7 PMID: 11858839
  99. Drosophila clipper/CPSF 30K is a post-transcriptionally regulated nuclear protein that binds RNA containing GC clusters.
    Nucleic Acids Res. 1998 Apr 1;26(7):1597-604 PMID: 9512528
  100. Translational control of cyclin B1 mRNA during meiotic maturation: coordinated repression and cytoplasmic polyadenylation.
    Dev Biol. 2000 Apr 1;220(1):97-109 PMID: 10720434
  101. Mobilization of specific maternal RNA species into polysomes after fertilization in Xenopus laevis.
    Proc Natl Acad Sci U S A. 1985 Nov;82(22):7636-40 PMID: 2415967
  102. Regulated Pumilio-2 binding controls RINGO/Spy mRNA translation and CPEB activation.
    Genes Dev. 2006 Jan 15;20(2):199-209 PMID: 16418484
  103. Recruitment of Nanos to hunchback mRNA by Pumilio.
    Genes Dev. 1999 Oct 15;13(20):2704-12 PMID: 10541556
  104. CUG-BP1/CELF1 requires UGU-rich sequences for high-affinity binding.
    Biochem J. 2006 Dec 1;400(2):291-301 PMID: 16938098
  105. XGef mediates early CPEB phosphorylation during Xenopus oocyte meiotic maturation.
    Mol Biol Cell. 2005 Mar;16(3):1152-64 PMID: 15635100
  106. Mechanism of degradation of CPEB during Xenopus oocyte maturation.
    Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18001-6 PMID: 17986610
  107. Biphasic activation of Aurora-A kinase during the meiosis I- meiosis II transition in Xenopus oocytes.
    Mol Cell Biol. 2003 Mar;23(5):1703-16 PMID: 12588989
  108. Evidence that polyadenylation factor CPSF-73 is the mRNA 3' processing endonuclease.
    RNA. 2004 Apr;10(4):565-73 PMID: 15037765
  109. PUF proteins bind Pop2p to regulate messenger RNAs.
    Nat Struct Mol Biol. 2006 Jun;13(6):533-9 PMID: 16715093
  110. A novel method for poly(A) fractionation reveals a large population of mRNAs with a short poly(A) tail in mammalian cells.
    Nucleic Acids Res. 2007;35(19):e132 PMID: 17933768
  111. Cell-cycle related regulation of poly(A) polymerase by phosphorylation.
    Nature. 1996 Nov 21;384(6606):282-5 PMID: 8918882
  112. Cloning and characterization of a Xenopus poly(A) polymerase.
    Mol Cell Biol. 1995 Mar;15(3):1422-30 PMID: 7862135
  113. Further analysis of cytoplasmic polyadenylation in Xenopus embryos and identification of embryonic cytoplasmic polyadenylation element-binding proteins.
    Mol Cell Biol. 1994 Dec;14(12):7867-75 PMID: 7969126
  114. Calcium, calmodulin, and CaMKII requirement for initiation of centrosome duplication in Xenopus egg extracts.
    Science. 2002 Jan 18;295(5554):499-502 PMID: 11799245
  115. ElrA binding to the 3'UTR of cyclin E1 mRNA requires polyadenylation elements.
    Nucleic Acids Res. 2007;35(7):2167-76 PMID: 17355986
  116. Translational control of the embryonic cell cycle.
    Cell. 2002 May 17;109(4):473-83 PMID: 12086604
  117. Autoregulation of GLD-2 cytoplasmic poly(A) polymerase.
    RNA. 2007 Feb;13(2):188-99 PMID: 17164476
  118. Interaction between a poly(A)-specific ribonuclease and the 5' cap influences mRNA deadenylation rates in vitro.
    Mol Cell. 2000 Mar;5(3):479-88 PMID: 10882133
  119. A dependent pathway of cytoplasmic polyadenylation reactions linked to cell cycle control by c-mos and CDK1 activation.
    Mol Biol Cell. 1997 Aug;8(8):1633-48 PMID: 9285830
  120. Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase.
    EMBO J. 2004 Feb 11;23(3):616-26 PMID: 14749727
  121. Mammalian GLD-2 homologs are poly(A) polymerases.
    Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4407-12 PMID: 15070731
  122. Cloning by differential screening of a Xenopus cDNA coding for a protein highly homologous to cdc2.
    Proc Natl Acad Sci U S A. 1991 Feb 1;88(3):1039-43 PMID: 1704128
  123. Poly (A) polymerases in the nucleus and cytoplasm of frog oocytes: dynamic changes during oocyte maturation and early development.
    RNA. 1995 Mar;1(1):64-78 PMID: 7489490
  124. Regulated polyadenylation controls mRNA translation during meiotic maturation of mouse oocytes.
    Genes Dev. 1989 Dec;3(12B):2163-71 PMID: 2483395
  125. Cytoplasmic polyadenylation element (CPE)- and CPE-binding protein (CPEB)-independent mechanisms regulate early class maternal mRNA translational activation in Xenopus oocytes.
    J Biol Chem. 2004 Apr 23;279(17):17650-9 PMID: 14752101
  126. HSF1 modulation of Hsp70 mRNA polyadenylation via interaction with symplekin.
    J Biol Chem. 2004 Mar 12;279(11):10551-5 PMID: 14707147
  127. The translational regulator CPEB1 provides a link between dcp1 bodies and stress granules.
    J Cell Sci. 2005 Mar 1;118(Pt 5):981-92 PMID: 15731006
  128. Maskin is a CPEB-associated factor that transiently interacts with elF-4E.
    Mol Cell. 1999 Dec;4(6):1017-27 PMID: 10635326
  129. Possible role of mouse poly(A) polymerase mGLD-2 during oocyte maturation.
    Dev Biol. 2006 Jan 1;289(1):115-26 PMID: 16325797
  130. Vertebrate GLD2 poly(A) polymerases in the germline and the brain.
    RNA. 2005 Jul;11(7):1117-30 PMID: 15987818
  131. Control of poly(A) polymerase level is essential to cytoplasmic polyadenylation and early development in Drosophila.
    EMBO J. 2002 Dec 2;21(23):6603-13 PMID: 12456666
  132. A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans.
    Nature. 2002 Sep 19;419(6904):312-6 PMID: 12239571
  133. Maturation-specific polyadenylation and translational control: diversity of cytoplasmic polyadenylation elements, influence of poly(A) tail size, and formation of stable polyadenylation complexes.
    Mol Cell Biol. 1990 Nov;10(11):5634-45 PMID: 1700272
  134. The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells.
    Genes Dev. 2003 Feb 1;17(3):336-41 PMID: 12569123
  135. CUG-BP binds to RNA substrates and recruits PARN deadenylase.
    RNA. 2006 Jun;12(6):1084-91 PMID: 16601207
  136. Hsp90 is required for c-Mos activation and biphasic MAP kinase activation in Xenopus oocytes.
    EMBO J. 2000 Apr 3;19(7):1516-24 PMID: 10747020
  137. Oocyte maturation, Mos and cyclins--a matter of synthesis: two functionally redundant ways to induce meiotic maturation.
    Cell Cycle. 2006 Jun;5(11):1152-9 PMID: 16760654
  138. Transient translational silencing by reversible mRNA deadenylation.
    Cell. 1992 Jun 12;69(6):1021-30 PMID: 1606611
  139. G beta gamma signaling reduces intracellular cAMP to promote meiotic progression in mouse oocytes.
    Steroids. 2007 Feb;72(2):117-23 PMID: 17178138
  140. Mechanisms regulating oocyte meiotic resumption: roles of mitogen-activated protein kinase.
    Mol Endocrinol. 2007 Sep;21(9):2037-55 PMID: 17536005
  141. Mechanisms of translational control by the 3' UTR in development and differentiation.
    Semin Cell Dev Biol. 2005 Feb;16(1):49-58 PMID: 15659339
  142. Sequence-specific adenylations and deadenylations accompany changes in the translation of maternal messenger RNA after fertilization of Spisula oocytes.
    J Mol Biol. 1983 May 25;166(3):309-27 PMID: 6854649
  143. Cleavage and polyadenylation factor CPF specifically interacts with the pre-mRNA 3' processing signal AAUAAA.
    EMBO J. 1991 Dec;10(13):4241-9 PMID: 1756731
  144. Poly(A) addition during maturation of frog oocytes: distinct nuclear and cytoplasmic activities and regulation by the sequence UUUUUAU.
    Genes Dev. 1989 Dec;3(12B):2151-62 PMID: 2628165
  145. Differential mRNA translation and meiotic progression require Cdc2-mediated CPEB destruction.
    EMBO J. 2002 Apr 2;21(7):1833-44 PMID: 11927567
  146. A novel endonuclease activity associated with the Arabidopsis ortholog of the 30-kDa subunit of cleavage and polyadenylation specificity factor.
    Nucleic Acids Res. 2007;35(13):4453-63 PMID: 17576667
  147. The roles of cytoplasmic poly(A)-binding proteins in regulating gene expression: a developmental perspective.
    Brief Funct Genomic Proteomic. 2004 Aug;3(2):125-41 PMID: 15355595
  148. The cleavage and polyadenylation specificity factor in Xenopus laevis oocytes is a cytoplasmic factor involved in regulated polyadenylation.
    Mol Cell Biol. 1999 Aug;19(8):5707-17 PMID: 10409759
  149. CPEB controls oocyte growth and follicle development in the mouse.
    Development. 2006 Nov;133(22):4527-37 PMID: 17050619
  150. ZYG-9, TAC-1 and ZYG-8 together ensure correct microtubule function throughout the cell cycle of C. elegans embryos.
    J Cell Sci. 2007 Aug 15;120(Pt 16):2963-73 PMID: 17666432
  151. Maturation-specific polyadenylation: in vitro activation by p34cdc2 and phosphorylation of a 58-kD CPE-binding protein.
    Genes Dev. 1991 Sep;5(9):1697-708 PMID: 1653174
  152. The mitogen-activated protein kinase signaling pathway stimulates mos mRNA cytoplasmic polyadenylation during Xenopus oocyte maturation.
    Mol Cell Biol. 1999 Mar;19(3):1990-9 PMID: 10022886
  153. A novel regulatory element determines the timing of Mos mRNA translation during Xenopus oocyte maturation.
    EMBO J. 2002 Jun 3;21(11):2798-806 PMID: 12032092
Article Info
Journal
Biochimica et biophysica acta
Abbr.
Biochim Biophys Acta
ISSN
0006-3002
DOI
10.1016/j.bbagrm.2008.02.002
Published
2008-04-00
Epub
2008-00-14
Pages
217-29
Language
English
Region
Netherlands
NLM ID
0217513
PMCID
PMC2323027
Subset
IM
Grants
Wellcome Trust · United Kingdom
External Links
PubMed source DOI: 10.1016/j.bbagrm.2008.02.002 PMC Full Text
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