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PMID: 6308576 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Complete nucleotide sequence of the Escherichia coli gdhA gene.

Nucleic acids research ·Vol. 11 ·No. 15 ·1983-08-11 ·Pages 5257-66

McPherson MJ, Wootton JC

Abstract

The DNA sequence of the gdhA gene of Escherichia coli K12, which encodes the 447 amino acid polypeptide subunit of NADP-specific glutamate dehydrogenase, is presented. The deduced protein sequence is strongly homologous to the corresponding enzyme of the eukaryotic fungus Neurospora crassa. The upstream DNA sequence includes several overlapping promoter consensus sequences. The downstream DNA sequence contains inverted repeats, predicted as forming long stable stem-loop structures in RNA, homologous to those found in several enterobacterial intergenic regions.

MeSH Terms
Amino Acid Sequence Base Sequence DNA Restriction Enzymes Escherichia coli/enzymology,genetics Genes Genes, Bacterial Glutamate Dehydrogenase/genetics Macromolecular Substances Neurospora crassa/enzymology,genetics Species Specificity
Chemicals
Macromolecular Substances Glutamate Dehydrogenase DNA Restriction Enzymes
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
McPherson M J
Wootton J C
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37 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/11.15.5257
Published
1983-08-11
Pages
5257-66
Language
English
Region
England
NLM ID
0411011
PMCID
PMC326259
Subset
IM
Databases
GENBANK
J01615, K00565
External Links
PubMed source DOI: 10.1093/nar/11.15.5257 PMC Full Text View journal details
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