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PMID: 6278410 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Apple II software for M13 shotgun DNA sequencing.

Nucleic acids research ·Vol. 10 ·No. 1 ·1982-01-11 ·Pages 39-49

Larson R, Messing J

Abstract

A set of programs is presented for the reconstruction of a DNA sequence from data generated by the M13 shotgun sequencing technique. Once the sequence has been established and stored other programs are used for its analysis. The programs have been written for the Apple II microcomputer. A minimum investment is required for the hardware and the software is easily interchangeable between the growing number of interested researchers. Copies are available in ready to use form.

MeSH Terms

Base Sequence Computers DNA DNA Restriction Enzymes/metabolism Methods Microcomputers Substrate Specificity

Chemicals

DNA DNA Restriction Enzymes

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Larson R

Messing J

References (3)

3 references, click to expand

Sequence data handling by computer.
Nucleic Acids Res. 1977 Nov;4(11):4037-51 PMID: 593900
A new computer method for the storage and manipulation of DNA gel reading data.
Nucleic Acids Res. 1980 Aug 25;8(16):3673-94 PMID: 7433103
A system for shotgun DNA sequencing.
Nucleic Acids Res. 1981 Jan 24;9(2):309-21 PMID: 6259625

Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/10.1.39

Published

1982-01-11

Pages

39-49

Language

English

Region

England

NLM ID

0411011

PMCID

PMC326112

Subset

External Links

PubMed source DOI: 10.1093/nar/10.1.39 PMC Full Text View journal details

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Apple II software for M13 shotgun DNA sequencing.

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