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PMID: 6302313 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Restriction and modification in Bacillus subtilis: DNA methylation potential of the related bacteriophages Z, SPR, SP beta, phi 3T, and rho 11.

Journal of virology ·Vol. 46 ·No. 2 ·1983-05-00 ·Pages 446-53

Noyer-Weidner M, Jentsch S, Pawlek B, Günthert U, Trautner TA

Abstract

The DNA methylation capacity and some other properties of the related temperate Bacillus subtilis phages Z, SPR, SP beta, phi 3T, and rho 11 are compared. With phage mutants affected in their methylation potential, we show that phage-coded methyltransferase genes are interchangeable among the phages studied. DNA/DNA hybridization experiments indicate that phage methyltransferase genes are structurally related, whereas no such relationship is observed to a bacterial gene, specifying a methyltransferase with the same specificity.

MeSH Terms
Bacillus subtilis Bacteriophages/enzymology,genetics Base Sequence DNA (Cytosine-5-)-Methyltransferases/genetics DNA Restriction Enzymes DNA, Viral/metabolism Genes, Viral Methylation Methyltransferases/genetics Mutation Nucleic Acid Hybridization
Chemicals
DNA, Viral Methyltransferases DNA (Cytosine-5-)-Methyltransferases DNA Restriction Enzymes
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Noyer-Weidner M
Jentsch S
Pawlek B
Günthert U
Trautner T A
References (27)
27 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.46.2.446-453.1983
Published
1983-05-00
Pages
446-53
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC255146
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.46.2.446-453.1983 PMC Full Text View journal details
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