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PMID: 6269059 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

DNA methyltransferases affecting the sequence 5'CCGG.

Nucleic acids research ·Vol. 9 ·No. 12 ·1981-06-25 ·Pages 2753-9

Jentsch S, Günthert U, Trautner TA

Abstract

B. subtilis phage SPbeta and Moraxella sp. code for DNA methyltransferases which methylate both cytosines of the sequence 5'CCGG. Experiments using a B. subtilis strain whose DNA is sensitive to HpaII and resistant to MspI degradation, indicated that methylation of the outer C of this sequence provides protection against the restriction enzyme MspI.

MeSH Terms
Bacillus subtilis/enzymology,genetics Bacteriophages/enzymology,genetics Base Sequence DNA (Cytosine-5-)-Methyltransferases/genetics DNA Restriction Enzymes DNA, Bacterial/genetics Methyltransferases/genetics Moraxella/enzymology,genetics Substrate Specificity
Chemicals
DNA, Bacterial Methyltransferases DNA (Cytosine-5-)-Methyltransferases DNA Restriction Enzymes
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Jentsch S
Günthert U
Trautner T A
References (17)
17 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/9.12.2753
Published
1981-06-25
Pages
2753-9
Language
English
Region
England
NLM ID
0411011
PMCID
PMC326890
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/9.12.2753 PMC Full Text View journal details
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