Elimination of plasmids by new 4-quinolones.

Antimicrobial agents and chemotherapy ·Vol. 28 ·No. 5 ·1985-11-00 ·Pages 700-2

Weisser J, Wiedemann B

Abstract

Nalidixic acid and six of the new 4-quinolones eliminated F'lac and various native R plasmids from Escherichia coli at one half or one quarter the MIC. Four of eight plasmids tested were cured by all derivatives, with frequencies from 10 to 98%. Quinolones did not eliminate all plasmids that were cured by novobiocin, and vice versa.

MeSH Terms

Drug Resistance, Microbial Escherichia coli/drug effects,genetics Microbial Sensitivity Tests Plasmids/drug effects Quinolines/pharmacology

Chemicals

Quinolines

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Weisser J

Wiedemann B

References (26)

26 references, click to expand

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Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.28.5.700

Published

1985-11-00

Pages

700-2

Language

English

Region

United States

NLM ID

0315061

PMCID

PMC176363

Subset

External Links

PubMed source DOI: 10.1128/AAC.28.5.700 PMC Full Text View journal details

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Elimination of plasmids by new 4-quinolones.

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