Home LiteratureArticle Details
PMID: 3016478 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Conservation and variation in the large scale organisation of the globin gene domains of duck and chicken.

Molecular & general genetics : MGG ·Vol. 203 ·No. 2 ·1986-05-00 ·Pages 193-201

Kretsovali A, Marcaud L, Moreau J, Scherrer K

Abstract

The genomic DNA of cloned recombinants containing the duck globin genes was compared to that of the analogous domains of the chicken. A 36 kb insert including the three alpha-type globin genes was isolated from a newly prepared duck genomic library in the cosmid PJB8; another recombinant contained a 45 kb insert with the four beta globin genes. In the alpha globin gene domain, the relative positions of genes, of repetitive sequences, and of the A + T-rich segments (AT-rich linkers, ATRLs) which frame the gene cluster (Moreau et al. 1982), were found to be closely maintained between duck and chicken. Although ATRLs and repetitive sequences also frame the gene cluster in the beta globin domains of duck and chicken, there is more genetic drift in their relative positions than in the alpha domain. It is of interest that several repetitive DNA segments were detected in the chicken beta globin domain which do not exist in corresponding positions in the duck. In view of the strict conservation in both species of genes and their relative positions in the cluster, this observation seems to exclude a simple function of repetitive sequences in the control of individual genes. The data are discussed with regard to the possible significance of repetitive and AT-rich DNA segments in genome organisation and function.

MeSH Terms
Animals Chickens Cloning, Molecular Cosmids DNA Restriction Enzymes Ducks Genes Genetic Variation Globins/genetics Nucleic Acid Denaturation Nucleic Acid Hybridization Repetitive Sequences, Nucleic Acid Species Specificity
Chemicals
Globins DNA Restriction Enzymes
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Kretsovali A
Marcaud L
Moreau J
Scherrer K
References (65)
65 references, click to expand
  1. Analysis of the adult chicken beta-globin gene. Nucleotide sequence of the locus, microheterogeneity at the 5'-end of beta-globin mRNA, and aberrant nuclear RNA species.
    J Biol Chem. 1983 Mar 25;258(6):3983-90 PMID: 6833240
  2. The isolation and partial characterization of linked alpha A- and alpha D-globin genes from a duck DNA recombinant library.
    Gene. 1982 May;18(2):187-91 PMID: 6290322
  3. Gene regulation for higher cells: a theory.
    Science. 1969 Jul 25;165(3891):349-57 PMID: 5789433
  4. An improved method for detecting foreign DNA in plasmids of Escherichia coli.
    Anal Biochem. 1979 Sep 15;98(1):60-3 PMID: 120689
  5. Molecular cloning and characterization of the human beta-like globin gene cluster.
    Cell. 1980 Apr;19(4):959-72 PMID: 6155216
  6. Rapid purification of plasmid DNAs by hydroxyapatite chromatography.
    Eur J Biochem. 1978 Nov 2;91(1):303-10 PMID: 363426
  7. Rapid and efficient cosmid cloning.
    Nucleic Acids Res. 1981 Jul 10;9(13):2989-98 PMID: 6269067
  8. Transcription in vivo of an Alu family member upstream from the human epsilon-globin gene.
    Nucleic Acids Res. 1984 Jan 25;12(2):1193-200 PMID: 6320117
  9. Synthesis in vitro of an exceptionally long RNA transcript promoted by an AluI sequence.
    Nature. 1982 Nov 25;300(5890):376-9 PMID: 7144892
  10. The primary structure of the duck alpha D-globin gene: an unusual 5' splice junction sequence.
    EMBO J. 1983;2(8):1339-43 PMID: 10872328
  11. DNA methylation in chicken alpha-globin gene expression.
    Proc Natl Acad Sci U S A. 1982 Sep;79(17):5332-6 PMID: 6291038
  12. Packaging recombinant DNA molecules into bacteriophage particles in vitro.
    Proc Natl Acad Sci U S A. 1977 Aug;74(8):3259-63 PMID: 333431
  13. Expression and partial DNA sequence of the chicken beta H-globin gene.
    J Biol Chem. 1983 Jan 25;258(2):802-9 PMID: 6296082
  14. An electron microscope study of the DNA sequence organization of the human genome.
    J Mol Biol. 1976 Sep 25;106(3):773-90 PMID: 988187
  15. The 5' ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I.
    Nature. 1980 Aug 28;286(5776):854-60 PMID: 6774262
  16. Chromosomal arrangement of the duck alpha-globin genes and primary structure of the embryonic alpha-globin gene pi.
    Gene. 1984 Dec;32(1-2):161-70 PMID: 6530142
  17. Unusual organization of DNA sequences in the chicken.
    Biochemistry. 1978 Dec 26;17(26):5838-44 PMID: 728440
  18. Nuclear matrix DNA from chicken erythrocytes contains beta-globin gene sequences.
    Proc Natl Acad Sci U S A. 1984 Jan;81(2):304-7 PMID: 6582488
  19. Nucleotide sequence of the rightward operator of phage lambda.
    Proc Natl Acad Sci U S A. 1975 Mar;72(3):1184-8 PMID: 1055375
  20. Ruminant globin gene structures suggest an evolutionary role for Alu-type repeats.
    Nucleic Acids Res. 1984 Feb 10;12(3):1641-55 PMID: 6322113
  21. Isolation and characterization of the complete chicken beta-globin gene region: frequent deletion of the adult beta-globin genes in lambda.
    Nucleic Acids Res. 1981 Aug 11;9(15):3731-46 PMID: 6269092
  22. Regulation of gene expression: possible role of repetitive sequences.
    Science. 1979 Jun 8;204(4397):1052-9 PMID: 451548
  23. A simple method of preparing large amounts of phiX174 RF 1 supercoiled DNA.
    Biochim Biophys Acta. 1973 Apr 11;299(4):516-20 PMID: 4575181
  24. DNAase I-hypersensitive sites of chromatin.
    Cell. 1981 Dec;27(3 Pt 2):413-5 PMID: 6101195
  25. Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold.
    Cell. 1984 Nov;39(1):223-32 PMID: 6091913
  26. The chicken beta globin gene region. Delineation of transcription units and developmental regulation of interspersed DNA repeats.
    J Biol Chem. 1982 Sep 25;257(18):11015-23 PMID: 6286679
  27. Nucleotide sequence analysis of a cloned duck beta-globin cDNA.
    Gene. 1981 Jun-Jul;14(1-2):11-21 PMID: 6894908
  28. Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms.
    Science. 1968 Aug 9;161(3841):529-40 PMID: 4874239
  29. cDNA sequence of a new chicken embryonic rho-globin.
    Proc Natl Acad Sci U S A. 1981 Aug;78(8):4782-5 PMID: 6170981
  30. Selective digestion of transcriptionally active ovalbumin genes from oviduct nuclei.
    Proc Natl Acad Sci U S A. 1976 Nov;73(11):3966-70 PMID: 1069279
  31. Mapping of structural and transcription-related matrix attachment sites in the alpha-globin gene domain of avian erythroblasts and erythrocytes.
    Mol Cell Biol. 1990 Oct;10(10):5349-58 PMID: 2398893
  32. Brain-specific genes have identifier sequences in their introns.
    Proc Natl Acad Sci U S A. 1984 Feb;81(3):713-7 PMID: 6583673
  33. Systematic punctuation of eukaryotic DNA by A+T-rich sequences.
    Proc Natl Acad Sci U S A. 1981 Mar;78(3):1341-5 PMID: 6940161
  34. The size of the transcriptional units of the avian globin genes defined at the pre-messenger RNA level.
    J Mol Biol. 1980 Jul 15;140(4):481-504 PMID: 7431397
  35. Nucleotide sequence for a novel duck alpha-globin gene.
    Eur J Biochem. 1981 Jul;117(2):269-73 PMID: 6895064
  36. Gene evolution in the chicken beta-globin cluster.
    Cell. 1982 Mar;28(3):515-21 PMID: 6896168
  37. Adult chicken alpha-globin genes alpha A and alpha D: no anemic shock alpha-globin exists in domestic chickens.
    Proc Natl Acad Sci U S A. 1981 Oct;78(10):5998-6002 PMID: 6273837
  38. A rapid alkaline extraction procedure for screening recombinant plasmid DNA.
    Nucleic Acids Res. 1979 Nov 24;7(6):1513-23 PMID: 388356
  39. The complete nucleotide sequence of the duck alpha A-globin gene.
    Gene. 1982 Dec;20(2):211-7 PMID: 7166233
  40. Chromosomal subunits in active genes have an altered conformation.
    Science. 1976 Sep 3;193(4256):848-56 PMID: 948749
  41. A simple method for DNA restriction site mapping.
    Nucleic Acids Res. 1976 Sep;3(9):2387-98 PMID: 787937
  42. DNA sequence organisation in avian genomes.
    Chromosoma. 1978 Dec 6;69(3):307-21 PMID: 743901
  43. The nucleotide sequence of the adult chicken alpha-globin genes.
    J Biol Chem. 1983 Apr 10;258(7):4623-9 PMID: 6300093
  44. Synthesis of double-stranded DNA complementary to lysozyme, ovomucoid, and ovalbumin mRNAs. Optimization for full length second strand synthesis by Escherichia coli DNA polymerase I.
    J Biol Chem. 1978 Apr 10;253(7):2483-95 PMID: 75887
  45. A + T-rich linkers define functional domains in eukaryotic DNA.
    Nature. 1982 Jan 21;295(5846):260-2 PMID: 6460190
  46. Unusual structure of the chicken embryonic alpha-globin gene, pi'.
    Proc Natl Acad Sci U S A. 1983 Mar;80(5):1392-6 PMID: 6572397
  47. Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.
    Proc Natl Acad Sci U S A. 1979 Aug;76(8):3683-7 PMID: 291033
  48. Repeated sequence organization and RNA transcription map of the chicken adult beta-globin gene region.
    J Biol Chem. 1981 Feb 25;256(4):1502-6 PMID: 6161922
  49. 5' Domain and nucleotide sequence of an adult chicken chromosomal beta-globin gene.
    Biochemistry. 1981 Apr 14;20(8):2091-8 PMID: 6263308
  50. The organization of repetitive sequences in a cluster of rabbit beta-like globin genes.
    Cell. 1980 Feb;19(2):379-91 PMID: 6244107
  51. Chromosomal arrangement of the chicken beta-type globin genes.
    Cell. 1981 Jun;24(3):669-77 PMID: 7249078
  52. DNA methylation and gene function.
    Science. 1980 Nov 7;210(4470):604-10 PMID: 6254144
  53. Alpha-Globin-gene switching during the development of chicken embryos: expression and chromosome structure.
    Cell. 1981 May;24(2):333-44 PMID: 7237551
  54. Characterization of duck genome fragments containing beta and epsilon globin genes.
    Gene. 1984 Nov;31(1-3):59-64 PMID: 6526275
  55. Determination of the primary sequence of the duck alpha D globin mRNA and comparison of all adult duck and chick globin mRNA sequences.
    Mol Biol Rep. 1983 May;9(1-2):101-13 PMID: 6888376
  56. Repetitive sequences in eukaryotic DNA and their expression.
    Annu Rev Biochem. 1982;51:813-44 PMID: 7051966
  57. Characterization of deoxyribonucleic acid sequences at the 5' and 3' borders of the 100 kilobase pair ovalbumin gene domain.
    Biochemistry. 1983 Jan 18;22(2):306-15 PMID: 6297544
  58. Isolation of beta-globin-related genes from a human cosmid library.
    Gene. 1981 Apr;13(3):227-37 PMID: 6266915
  59. A sequence related to 4.5 S RNA and the B1 family of repeated DNA in the 5' flanking region of the mouse beta-globin gene.
    J Mol Biol. 1983 Oct 5;169(4):975-82 PMID: 6195342
  60. Biochemical evolution.
    Annu Rev Biochem. 1977;46:573-639 PMID: 409339
  61. Comparative aspects of DNA organization in Metazoa.
    Chromosoma. 1975 Jul 21;51(3):253-9 PMID: 238803
  62. Isolation of the chicken beta-globin gene and a linked embryonic beta-like globin gene from a chicken DNA recombinant library.
    Cell. 1979 Aug;17(4):879-87 PMID: 158428
  63. Nucleotide sequences for the duck globin mRNAs.
    J Mol Appl Genet. 1984;2(4):381-91 PMID: 6547470
  64. Localization and characterization of members of a family of repetitive sequences in the goat beta globin locus.
    Nucleic Acids Res. 1985 Mar 25;13(6):2171-86 PMID: 4000955
  65. Correlations of repetitive and AT-rich DNA segments within the chicken globin gene domains.
    Mol Biol Rep. 1986;11(3):177-87 PMID: 3020393
Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00333954
Published
1986-05-00
Pages
193-201
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00333954
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2