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PMID: 20022735 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Mechanochemical crosstalk during endocytic vesicle formation.

Current opinion in cell biology ·Vol. 22 ·No. 1 ·2010-02-00 ·Pages 36-43

Liu J, Sun Y, Oster GF, Drubin DG

Abstract

Membrane curvature has emerged as a key regulatory factor in endocytic vesicle formation. From a theoretical perspective, we summarize recent progress in understanding how membrane curvature and biochemical pathways are coupled and orchestrated during the coherent process of endocytic vesicle formation. We mainly focus on clathrin-mediated and actin-mediated endocytosis in yeast and in mammalian cells. We further speculate on how mechanochemical feedback could modulate other membrane-remodeling processes.

MeSH Terms
Actins/metabolism Animals Clathrin/metabolism Dynamins/metabolism Endocytosis/physiology Lipid Bilayers/chemistry,metabolism Models, Biological Signal Transduction/physiology Transport Vesicles/chemistry,metabolism,ultrastructure
Chemicals
Actins Clathrin Lipid Bilayers Dynamins
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Liu Jian
Department of Molecular and Cell Biology, UC-Berkeley, United States.
Sun Yidi
Oster George F
Drubin David G
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Article Info
Journal
Current opinion in cell biology
Abbr.
Curr Opin Cell Biol
ISSN
1879-0410
DOI
10.1016/j.ceb.2009.11.009
Published
2010-02-00
Epub
2009-00-21
Pages
36-43
Language
English
Region
England
NLM ID
8913428
PMCID
PMC2822040
Subset
IM
Grants
NIGMS NIH HHS · R01 GM050399-13 · United States
NIGMS NIH HHS · R01 GM042759-17 · United States
NIGMS NIH HHS · 1 R01 GM 42759 · United States
NIGMS NIH HHS · R01 GM050399 · United States
NIGMS NIH HHS · R01 GM065462-07 · United States
NIGMS NIH HHS · 1 R01 GM 65462 · United States
NIGMS NIH HHS · 1 R01 GM 50399 · United States
NIGMS NIH HHS · R01 GM065462 · United States
NIGMS NIH HHS · R01 GM042759 · United States
External Links
PubMed source DOI: 10.1016/j.ceb.2009.11.009 PMC Full Text View journal details
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