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PMID: 13345964 Published · ppublish English Journal Article

The amino acid sequence of hypertensin. II.

The Journal of experimental medicine ·Vol. 104 ·No. 2 ·1956-08-01 ·Pages 193-7

SKEGGS LT, LENTZ KE, KAHN JR, SHUMWAY NP, WOODS KR

Abstract

The amino acid sequence of horse hypertensin II has been determined by the use of chymotrypsin, the fluorodinitrobenzene method, and stepwise phenylisothiocyanate degradation. The results indicate that the amino acids of hypertensin II are arranged in the following order: asp-arg-val-tyr-iso-hist-pro-phe.

Keywords
AMINO ACIDS/determination ANGIOTONIN
MeSH Terms
Amino Acid Sequence Amino Acids/analysis Angiotensin Amide Angiotensins Animals Chymotrypsin Horses Trypsin
Chemicals
Amino Acids Angiotensins Angiotensin Amide Chymotrypsin Trypsin
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
SKEGGS L T
LENTZ K E
KAHN J R
SHUMWAY N P
WOODS K R
References (15)
15 references, click to expand
  1. A modified ninhydrin reagent for the photometric determination of amino acids and related compounds.
    J Biol Chem. 1954 Dec;211(2):907-13 PMID: 13221596
  2. The isolation and assay of hypertensin from blood.
    J Exp Med. 1952 Mar;95(3):241-6 PMID: 14927788
  3. The purification of hypertensin II.
    J Exp Med. 1956 Mar 1;103(3):301-7 PMID: 13295488
  4. Amino acid composition and electrophoretic properties of hypertensin I.
    J Exp Med. 1955 Oct 1;102(4):435-40 PMID: 13263485
  5. Recent developments in techniques for terminal and sequence studies in peptides and proteins.
    Methods Biochem Anal. 1955;2:359-425 PMID: 14393573
  6. The assay of hypertensin from the arterial blood of normotensive and hypertensive human beings.
    J Exp Med. 1952 Jun;95(6):523-9 PMID: 14946317
  7. The purification of hypertensin I.
    J Exp Med. 1954 Oct 1;100(4):363-70 PMID: 13201713
  8. A method of assaying small amounts of hypertensin.
    Lab Invest. 1953 Mar-Apr;2(2):109-14 PMID: 13045413
  9. Amino-acid sequence in a hypertensin.
    Nature. 1956 Mar 17;177(4507):527-8 PMID: 13321895
  10. The existence of two forms of hypertensin.
    J Exp Med. 1954 Mar;99(3):275-82 PMID: 13130799
  11. The preparation and function of the hypertensin-converting enzyme.
    J Exp Med. 1956 Mar 1;103(3):295-9 PMID: 13295487
  12. Chromatography of amino acids on sulfonated polystyrene resins.
    J Biol Chem. 1951 Oct;192(2):663-81 PMID: 14907661
  13. Countercurrent distribution.
    Methods Med Res. 1952;5:3-24 PMID: 13002089
  14. Isolation and purification of hog renin.
    Arch Biochem Biophys. 1953 Feb;42(2):368-86 PMID: 13031639
  15. The free amino groups of insulin.
    Biochem J. 1945;39(5):507-15 PMID: 16747948
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
DOI
10.1084/jem.104.2.193
Published
1956-08-01
Pages
193-7
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2136655
Subset
OM
External Links
PubMed source DOI: 10.1084/jem.104.2.193 PMC Full Text View journal details
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