Home LiteratureArticle Details
PMID: 1090629 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Messenger RNA metabolism of animal cells. Possible involvement of untranslated sequences and mRNA-associated proteins.

The Journal of cell biology ·Vol. 64 ·No. 2 ·1975-02-00 ·Pages 269-88

Greenberg JR

Abstract

The past several years have seen a virtual revolution in the study of eukaryotic mRNA. Among the notable recent achievements are the positive identification of mRNA precursors in HnRNA, the enumeration of the DNA sequences from which mRNA is transcribed, and the finding that mRNA in cultured cells is much more stable than was previously believed. One of most far-reaching discoveries has been the finding that mRNA in eukaryotes contains poly A. This discovery, aside from providing a powerful tool for mRNA isolation, has generated a large body of research into the properties and metabolism of poly A itself. In addition, the finding of a poly A-associated protein has given a renewed stimulus to the study of proteins associated with mRNA. This review is devoted to a discussion of these and related achievements, and some of their implications

MeSH Terms
Adenine Adenosine/metabolism Animals Base Sequence Cell Nucleus/analysis,metabolism Cytoplasm/metabolism Genes Humans Nucleic Acid Hybridization Nucleoproteins/metabolism Polynucleotides/analysis,biosynthesis Protein Biosynthesis RNA/analysis RNA, Messenger/analysis,metabolism Transcription, Genetic Tritium
Chemicals
Nucleoproteins Polynucleotides RNA, Messenger Tritium RNA Adenine Adenosine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Greenberg J R
References (140)
140 references, click to expand
  1. Initiation of polyribosome formation in poliovirus-infected HeLa cells.
    J Mol Biol. 1970 Feb 14;47(3):275-91 PMID: 4313849
  2. Isolation of messenger ribonucleoproteins from mammalian cells.
    J Mol Biol. 1974 Jun 25;86(2):451-68 PMID: 4213207
  3. Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene.
    Proc Natl Acad Sci U S A. 1974 Sep;71(9):3659-63 PMID: 4215083
  4. Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse.
    J Mol Biol. 1974 Sep 5;88(1):43-63 PMID: 4216641
  5. Evolutionary stability of the histone genes of sea urchins.
    Biochemistry. 1973 Oct 9;12(21):4113-22 PMID: 4200893
  6. Mesenger ribonucleoprotein and initiation factors in rabbit-reticulocyte polyribosomes.
    Eur J Biochem. 1973 Mar 1;33(2):314-22 PMID: 4632818
  7. Polyadenylic acid in Visna virus RNA.
    Science. 1973 Mar 30;179(4080):1328-30 PMID: 4631425
  8. Cell-free translation of maternal messenger RNA from sea urchin eggs.
    Proc Natl Acad Sci U S A. 1973 Sep;70(9):2614-8 PMID: 4582192
  9. Adenylic acid-rich sequences in messenger RNA from yeast polysomes.
    FEBS Lett. 1973 Jun 1;32(2):213-7 PMID: 4582154
  10. Polyadenylic acid sequences in yeast messenger ribonucleic acid.
    J Biol Chem. 1973 Feb 25;248(4):1466-71 PMID: 4568819
  11. Genes coding for polysomal 9S RNA of sea urchins: conservation and divergence.
    Nature. 1972 Nov 24;240(5378):225-8 PMID: 4569419
  12. Elongation of the polyadenylate segment of messenger RNA in the cytoplasm of mammalian cells.
    Proc Natl Acad Sci U S A. 1974 Oct;71(10):4091-5 PMID: 4547843
  13. Covalent attachment of nucleic acids to agarose for affinity chromatography.
    Biochemistry. 1971 Feb 2;10(3):424-7 PMID: 5543969
  14. Preformed messenger of quiescent wheat embryos.
    Biochim Biophys Acta. 1971 Apr 8;232(4):671-84 PMID: 5556848
  15. Messenger RNA in HeLa cells: an investigation of free and polyribosome-bound cytoplasmic messenger ribonucleoprotein particles by kinetic labelling and electron microscopy.
    Eur J Biochem. 1970 Dec;17(2):296-318 PMID: 5500399
  16. Regulation of protein synthesis in mammalian cells. II. Inhibition of protein synthesis at the level of initiation during mitosis.
    J Mol Biol. 1970 Jun 28;50(3):655-70 PMID: 5529301
  17. Selective measurement of the synthesis and metabolic stability of messenger RNA in 3T3 mouse cells.
    Biochim Biophys Acta. 1970 Apr 15;204(2):449-61 PMID: 5462410
  18. Adenine-rich polymer associated with rabbit reticulocyte messenger RNA.
    Nature. 1970 Aug 15;227(5259):710-2 PMID: 5432070
  19. Interaction of HeLa cell proteins with RNA.
    J Mol Biol. 1970 Feb 14;47(3):263-73 PMID: 5418163
  20. The isolation and characterization of adenosine monophosphate-rich polynucleotides synthesized by Ehrlich ascites cells.
    J Biol Chem. 1969 Mar 10;244(5):1314-24 PMID: 5767312
  21. Persistence of messenger RNA through mitosis in HeLa cells.
    J Cell Biol. 1969 Feb;40(2):497-507 PMID: 5761922
  22. Breakdown and assembly of polyribosomes in synchronized Chinese hamster cells.
    Science. 1968 Aug 23;161(3843):791-3 PMID: 5663806
  23. In vivo labeling patterns of free polyribosomes: relationship to tape theory of messenger ribonucleic acid function.
    J Mol Biol. 1967 Jun 14;26(2):211-25 PMID: 6034773
  24. Polyadenylic acid in the cytoplasm of rat liver.
    J Mol Biol. 1966 Sep;20(1):1-7 PMID: 5970658
  25. POLYRIBOSOMES IN NORMAL AND POLIOVIRUS-INFECTED HELA CELLS AND THEIR RELATIONSHIP TO MESSENGER-RNA.
    Proc Natl Acad Sci U S A. 1963 May;49(5):654-62 PMID: 16591084
  26. PROTEIN SYNTHESIS IN ERYTHROID CELLS, I. RETICULOCYTE RIBOSOMES ACTIVE IN STIMULATING AMINO ACID INCORPORATION.
    Proc Natl Acad Sci U S A. 1962 Dec;48(12):2163-71 PMID: 16591030
  27. Polynucleotide biosynthesis: formation of a sequence of adenylate units from adenosine triphosphate by an enzyme from thymus nuclei.
    J Biol Chem. 1960 Apr;235:1142-9 PMID: 13819354
  28. MACROMOLECULE SYNTHESIS AND THE INFLUENCE OF ACTINOMYCIN ON EARLY DEVELOPMENT.
    Exp Cell Res. 1964 Feb;33:368-95 PMID: 14161546
  29. Synthesis and turnover of nuclear and cytoplasmic polyadenylic acid in mouse L cells.
    J Mol Biol. 1974 Jan 25;82(3):315-31 PMID: 4856346
  30. Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.
    Proc Natl Acad Sci U S A. 1972 Jun;69(6):1408-12 PMID: 4504350
  31. A comparison of globin genes in duck reticulocytes and liver cells.
    Biochem Biophys Res Commun. 1972 Nov 1;49(3):813-9 PMID: 4638756
  32. Evidence for single copies of globin genes in the mouse genome.
    Nature. 1972 Sep 22;239(5369):219-21 PMID: 4117010
  33. The duck-globin messenger-ribonucleoprotein complex. Resistance to high ionic strength, particle gel electrophoresis, composition and visualisation by dark-field electron microscopy.
    Eur J Biochem. 1973 Jul 16;36(2):455-64 PMID: 4738397
  34. Synthesis of rabbit globin by reticulocyte postribosomal supernatant and heterologous ribosomes.
    Eur J Biochem. 1973 Jun 15;35(3):559-65 PMID: 4730956
  35. Globin messenger sequences in high molecular weight RNA from embryonic mouse liver.
    Nat New Biol. 1973 Jan 17;241(107):66-8 PMID: 4512402
  36. Cell-free translation of the globin message within polydisperse high-molecular-weight ribonucleic acid of avian erythrocytes.
    Proc Natl Acad Sci U S A. 1973 Dec;70(12):3641-5 PMID: 4519651
  37. Messenger ribonucleoprotein-directed globin synthesis in an embryonic brain cell-free system.
    Biochim Biophys Acta. 1974 Mar 27;340(3):278-84 PMID: 4826256
  38. Translation of mouse globin messenger ribonucleic acid from which the poly(adenylic acid) sequence has been removed.
    Biochemistry. 1974 Feb 12;13(4):703-7 PMID: 4129862
  39. Message stability in injected frog oocytes: long life of mammalian alpha and beta globin messages.
    J Mol Biol. 1973 Nov 5;80(3):539-51 PMID: 4796973
  40. DNA-RNA hybridisation of 9S messenger RNA for mouse globin.
    Biochem Biophys Res Commun. 1970 Aug 11;40(3):740-5 PMID: 5492166
  41. Poly A sequences at the 3' termini of rabbit globin mRNAs.
    Nat New Biol. 1971 Sep 8;233(36):41-3 PMID: 5286353
  42. Role of the polyadenylate segment in the translation of globin messenger RNA in Xenopus oocytes.
    Proc Natl Acad Sci U S A. 1974 Aug;71(8):3143-6 PMID: 4528715
  43. Separation of specific initiation factors involved in the translation of myosin and myoglobin messenger RNAs and the isolation of a new RNA involved in translation.
    Proc Natl Acad Sci U S A. 1974 Jun;71(6):2428-31 PMID: 4526305
  44. mRNA stability and cellular differentiation.
    Acta Endocrinol Suppl (Copenh). 1972;168:319-45 PMID: 4538751
  45. Transcription of polydeoxythymidylate sequences in the genome of the cellular slime mold, Dictyostelium discoideum.
    Proc Natl Acad Sci U S A. 1974 May;71(5):1607-11 PMID: 4525281
  46. A small nuclear precursor of messenger RNA in the cellular slime mold Dictyostelium discoideum.
    J Mol Biol. 1973 Sep 15;79(2):295-314 PMID: 4796769
  47. The isolation and characterization of steady-state labeled messenger RNA from L-cells.
    Biochim Biophys Acta. 1972 Dec 6;287(2):361-6 PMID: 4680052
  48. Nucleotide clusters in deoxyribonucleic acids. Pyrimidine oligonucleotides of mouse L-cell satellite deoxyribonucleic acid and main-band deoxyribonucleic acid.
    Biochemistry. 1974 Mar 12;13(6):1094-101 PMID: 4856025
  49. In vitro synthesis of RNA that contains polyadenylate by virion-associated RNA polymerase of vesicular stomatitis virus.
    Proc Natl Acad Sci U S A. 1973 Dec;70(12):3566-70 PMID: 4357880
  50. Messenger RNA turnover in mouse L cells.
    J Mol Biol. 1973 Oct 5;79(4):681-96 PMID: 4796595
  51. Hybridization properties of DNA sequences directing the synthesis of messenger RNA and heterogeneous nuclear RNA.
    J Cell Biol. 1971 Sep;50(3):774-86 PMID: 4999767
  52. Lifetime of the messenger RNA's which code for ribosomal proteins in L-cells.
    Biochim Biophys Acta. 1971 Sep 24;246(3):493-8 PMID: 5142072
  53. Early appearance of histone messenger RNA in polyribosomes of cultured L cells.
    J Mol Biol. 1972 Feb 14;63(3):591-6 PMID: 4111381
  54. Characterization of the messenger RNA released from L cell polyribosomes as a result of temperature shock.
    J Mol Biol. 1972 Feb 14;63(3):577-90 PMID: 4622588
  55. On the lability of poly(A) sequences during extraction of messenger RNA from polyribosomes.
    Biochim Biophys Acta. 1972 Mar 14;262(2):220-6 PMID: 5017913
  56. Polyadenylic acid sequences: role in conversion of nuclear RNA into messenger RNA.
    Science. 1971 Oct 29;174(4008):507-10 PMID: 5110429
  57. Messenger RNA-protein complexes and newly synthesized ribosomal subunits: analysis of free particles and components of polyribosomes.
    J Mol Biol. 1968 Jul 14;35(1):37-59 PMID: 5000315
  58. The isolation of polyadenylate with unreacted cellulose.
    Biochem Biophys Res Commun. 1972 Jun 28;47(6):1426-37 PMID: 5040242
  59. Translation of bacteriophage Q RNA by cytoplasmic extracts of mammalian cells.
    Proc Natl Acad Sci U S A. 1973 Feb;70(2):315-9 PMID: 4568725
  60. Localization of polyadenylic acid sequences in messenger ribonucleic acid of mammalian cells.
    Biochemistry. 1972 Aug 15;11(17):3256-60 PMID: 5065478
  61. Lack of polyadenylic acid sequences in the messenger RNA of E. coli.
    Biochem Biophys Res Commun. 1972 Sep 26;48(6):1593-600 PMID: 4562159
  62. High stability of messenger RNA in growing cultured cells.
    Nature. 1972 Nov 10;240(5376):102-4 PMID: 4564814
  63. Polyadenylic acid sequences on 3' termini of vaccinia messenger ribonucleic acid and mammalian nuclear and messenger ribonucleic acid.
    Biochemistry. 1972 Sep 26;11(20):3829-34 PMID: 5072204
  64. Further evidence on the nuclear origin and transfer to the cytoplasm of polyadenylic acid sequences in mammalian cell RNA.
    J Mol Biol. 1973 Apr 15;75(3):515-32 PMID: 4125135
  65. Evidence that the polyadenylic acid segment of "35S" RNA of avian myeloblastosis virus is located at the 3'-OH terminus.
    Biochem Biophys Res Commun. 1973 Nov 1;55(1):8-16 PMID: 4362664
  66. Polyadenylic acid sequences in the virion RNA of poliovirus and Eastern Equine Encephalitis virus.
    Science. 1972 May 5;176(4034):526-8 PMID: 4338097
  67. Correlation of messenger RNA function with adenylate-rich segments in the genomes of single-stranded RNA viruses.
    Proc Natl Acad Sci U S A. 1972 Jun;69(6):1514-6 PMID: 4338595
  68. The genome of RNA tumor viruses contains polyadenylic acid sequences.
    Proc Natl Acad Sci U S A. 1972 Apr;69(4):791-4 PMID: 4337237
  69. Adenylic acid-rich sequence in RNAs of Rous sarcoma virus and Rauscher mouse leukaemia virus.
    Nature. 1972 Feb 18;235(5338):383-6 PMID: 4334604
  70. Ribonucleic acid synthesis in cells infected with herpes simplex virus. VI. Polyadenylic acid sequences in viral messenger ribonucleic acid.
    J Virol. 1972 Oct;10(4):875-9 PMID: 4343550
  71. Adenylate-rich sequences in vesicular stomatitis virus messenger ribonucleic acid.
    J Virol. 1972 Oct;10(4):683-8 PMID: 4343546
  72. Polyadenylic acid at the 3'-terminus of poliovirus RNA.
    Proc Natl Acad Sci U S A. 1972 Jul;69(7):1877-82 PMID: 4340162
  73. Localization of the polyadenylate sequences in messenger ribonucleic acid and in the heterogeneous nuclear ribonucleic acid of HeLa cells.
    J Biol Chem. 1973 Feb 25;248(4):1472-6 PMID: 4346958
  74. Nucleotide pools in Novikoff rat hepatoma cells growing in suspension culture. 3. Effects of nucleosides in medium on levels of nucleotides in separate nucleotide pools for nuclear and cytoplasmic RNA synthesis.
    J Cell Biol. 1972 Jan;52(1):131-46 PMID: 4331295
  75. Association of polyadenylic acid with messenger RNA of vesicular stomatitis virus.
    J Mol Biol. 1973 Jul 5;77(3):449-55 PMID: 4353720
  76. Polypeptide cleavages in the formation of poliovirus proteins.
    Proc Natl Acad Sci U S A. 1968 Sep;61(1):77-84 PMID: 4301595
  77. Transcription from unique and redundant DNA sequences in sea urchin embryos.
    Biochem Biophys Res Commun. 1974 Jan;56(1):47-51 PMID: 4823444
  78. The presence of polyriboadenylic acid sequences in calf lens messenger RNA.
    J Mol Biol. 1974 Jan 5;82(1):15-25 PMID: 4818481
  79. Stability of cytoplasmic ribonucleic acid in a mouse myeloma: estimation of the half-life of the messenger RNA coding for an immunoglobulin light chain.
    J Mol Biol. 1974 Feb 5;82(4):469-81 PMID: 4817791
  80. mRNA turnover studies applying labeled uridine require an evaluation of specific radioactivities of UTP and RNA-U.
    Biochem Biophys Res Commun. 1973 Nov 16;55(2):273-81 PMID: 4767304
  81. Translation of bacteriophage R17 and Qbeta RNA in a mammalian cell-free system.
    J Mol Biol. 1973 Apr 15;75(3):575-8 PMID: 4737561
  82. Histone mRNA in eggs and embryos of Strongylocentrotus purpuratus.
    Biochem Biophys Res Commun. 1973 Jul 17;53(2):515-22 PMID: 4736817
  83. Turnover of myeloma messenger DNA.
    Biochem Biophys Res Commun. 1973 Jun 19;52(4):1483-91 PMID: 4717760
  84. Messenger RNA in HeLa cells: kinetics of formation and decay.
    J Mol Biol. 1973 Aug 5;78(2):321-34 PMID: 4747634
  85. Regulation of protein synthesis in chick oviduct. 3. Mechanism of ovalbumin "superinduction" by actinomycin D.
    J Biol Chem. 1973 Mar 10;248(5):1502-12 PMID: 4694721
  86. Poly adenylic acid sequences in mitochondrial RNA.
    Biochem Biophys Res Commun. 1973 Apr 16;51(4):1090-6 PMID: 4703555
  87. Characterization of the poly(adenylic acid) regions and the adjacent nucleotides in heterogeneous nuclear ribonucleic acid and messenger ribonucleic acid from HeLa cells.
    Biochemistry. 1973 Jun 5;12(12):2324-30 PMID: 4710583
  88. Duck hemoglobin messenger RNA contains a polynucleotide sequence rich in adenylic acid.
    J Mol Biol. 1972 Apr 14;65(3):531-5 PMID: 5063356
  89. The genes for silk fibroin in Bombyx mori.
    J Mol Biol. 1972 Oct 14;70(3):637-49 PMID: 5083150
  90. Messenger RNA in rat liver polyribosomes: evidence that it exists as ribonucleoprotein particles.
    J Mol Biol. 1968 Sep 28;36(3):401-11 PMID: 5000204
  91. Relative occurrence of polyadenylic acid sequences in messenger and heterogeneous nuclear RNA of L cells as determined by poly (U)-hydroxylapatite chromatography.
    J Mol Biol. 1972 Dec 14;72(1):91-8 PMID: 4675125
  92. Characterization of poly(riboadenylic acid) segments in L-cell messenger ribonucleic acid.
    Biochemistry. 1973 Sep 25;12(20):3951-6 PMID: 4583316
  93. A protein of molecular weight 78,000 bound to the polyadenylate region of eukaryotic messenger RNAs.
    Proc Natl Acad Sci U S A. 1973 Mar;70(3):924-8 PMID: 4515002
  94. Reiteration frequency of haemoglobin genes in the duck.
    Nat New Biol. 1972 Feb 23;235(60):231-4 PMID: 4502410
  95. Reiteration and clustering of DNA sequences complementary to histone messenger RNA.
    Nat New Biol. 1971 Apr 7;230(14):165-9 PMID: 5279989
  96. Two proteins are bound to most species of polysomal mRNA.
    Nat New Biol. 1973 Aug 29;244(139):271-4 PMID: 4517007
  97. Polyadenylic acid segment in mRNA becomes shorter with age.
    Nat New Biol. 1973 Feb 28;241(113):265-8 PMID: 4511912
  98. Characteristic two-dimensional patterns of enzymatic digests of oncorna and other viral RNAs.
    Nat New Biol. 1972 Nov 22;240(99):105-9 PMID: 4345000
  99. Hybridization properties and sequence arrangement in a population of mRNAs.
    Nat New Biol. 1973 Mar 28;242(117):101-5 PMID: 4513407
  100. Poly(A) sequences in plant polysomal RNA.
    Nat New Biol. 1973 Nov 21;246(151):68-70 PMID: 4519107
  101. Poly A associated with SV40 messenger RNA.
    Nat New Biol. 1972 Jul 26;238(82):111-3 PMID: 4339960
  102. Further evidence for posttranscriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells.
    Nat New Biol. 1972 Sep 6;239(88):9-14 PMID: 4404031
  103. Isolation of feather keratin mRNA and its translation in a rabbit reticulocyte cell-free system.
    Nat New Biol. 1973 Nov 14;246(150):33-6 PMID: 4519025
  104. Stability of HeLa cell mRNA in actinomycin.
    Nature. 1972 Nov 10;240(5376):100-2 PMID: 4118029
  105. Evidence that all messenger RNA molecules (except histone messenger RNA) contain Poly (A) sequences and that the Poly(A) has a nuclear function.
    J Mol Biol. 1972 Oct 28;71(1):21-30 PMID: 4539023
  106. Messenger RNA for hepatic tryptophan oxygenase: its partial purification, its translation in a heterologous cell-free system, and its control by glucocorticoid hormones.
    Proc Natl Acad Sci U S A. 1973 Apr;70(4):1218-21 PMID: 4515620
  107. Purification of 14S messenger RNA of immunoglobulin light chain that codes for a possible light-chain precursor.
    Proc Natl Acad Sci U S A. 1973 Feb;70(2):451-5 PMID: 4510289
  108. Cytoplasmic adenylylation and processing of maternal RNA.
    Proc Natl Acad Sci U S A. 1973 Feb;70(2):406-11 PMID: 4510284
  109. Estimation of light-chain gene reiteration of mouse immunoglobulin by DNA-RNA hybridization.
    Proc Natl Acad Sci U S A. 1973 Jan;70(1):173-8 PMID: 4509648
  110. Stability of cytoplasmic messenger RNA in HeLa cels.
    Proc Natl Acad Sci U S A. 1973 Jan;70(1):115-9 PMID: 4509644
  111. A particle associated with the polyadenylate segment in mammalian messenger RNA.
    Proc Natl Acad Sci U S A. 1972 Nov;69(11):3247-50 PMID: 4508317
  112. Rates of induction of specific translatable messenger RNAs for ovalbumin and avidin by steroid hormones.
    Proc Natl Acad Sci U S A. 1973 Jun;70(6):1870-4 PMID: 4515943
  113. Distribution of repetitive and nonrepetivite sequence transcripts in HeLa mRNA.
    Proc Natl Acad Sci U S A. 1974 May;71(5):1785-9 PMID: 4525461
  114. Analysis of long pyrimidine polynucleotides in HeLa cell nuclear DNA: absence of polydeoxythymidylate.
    Proc Natl Acad Sci U S A. 1973 Aug;70(8):2189-92 PMID: 4525425
  115. Maternal histone messenger RNA: detection by molecular hybridization.
    Proc Natl Acad Sci U S A. 1973 Oct;70(10):2840-4 PMID: 4517937
  116. Interspersion of repetitive and single-copy sequences in nuclear ribonucleic acid of high molecular weight.
    Proc Natl Acad Sci U S A. 1974 Apr;71(4):1108-12 PMID: 4524620
  117. Polyadenylation of maternal RNA of sea urchin eggs after fertilization.
    Proc Natl Acad Sci U S A. 1973 Aug;70(8):2345-9 PMID: 4525169
  118. Biologically and chemically pure mRNA coding for a mouse immunoglobulin L-chain prepared with the aid of antibodies and immobilized oligothymidine.
    Proc Natl Acad Sci U S A. 1973 Aug;70(8):2256-60 PMID: 4525163
  119. Nonrepetitive DNA sequence representation in sea urchin embryo messenger RNA.
    Proc Natl Acad Sci U S A. 1973 Dec;70(12):3516-20 PMID: 4519642
  120. Estimation of the number of genes coding for the constant part of the mouse immunoglobulin kappa light chain.
    Proc Natl Acad Sci U S A. 1974 Jun;71(6):2491-5 PMID: 4526222
  121. Detection of polyadenylic acid sequences in viral and eukaryotic RNA(polu(U)-cellulose columns-poly(U) filters-fiberglass-HeLa cells-bacteriophage T4).
    Proc Natl Acad Sci U S A. 1972 Feb;69(2):417-21 PMID: 4501121
  122. Purification and properties of biologically active messenger RNA for a myeloma light chain.
    Proc Natl Acad Sci U S A. 1972 Jul;69(7):1967-71 PMID: 4505674
  123. Characterization of messenger ribonucleoprotein and messenger RNA from KB cells.
    Proc Natl Acad Sci U S A. 1972 Mar;69(3):681-5 PMID: 4501582
  124. Characteristics of the polyadenylic acid segment associated with messenger ribonucleic acid in mouse sarcoma 180 ascites cells.
    Biochemistry. 1972 Feb 29;11(5):792-8 PMID: 4536742
  125. Cytoplasmic ribonucleic acids with messenger characteristics in salivary gland cells of Chironomus tentans.
    J Mol Biol. 1974 Apr 25;84(4):569-83 PMID: 4841000
  126. Hybridization studies with an antibody heavy chain mRNA.
    FEBS Lett. 1974 Apr 15;41(1):73-7 PMID: 4852316
  127. Presumptive mRNA for procollagen: occurrence in membrane bound ribosomes of embryonic chick tendon fibroblasts.
    FEBS Lett. 1974 Apr 15;41(1):85-8 PMID: 4859449
  128. Evidence for multiple immunoglobulin genes.
    Biochem Biophys Res Commun. 1974 Mar 15;57(1):31-8 PMID: 4857184
  129. Relative positions of the "repetitive", "unique" and poly(A) fragments of mRNA.
    Nature. 1974 Apr 5;248(448):486-90 PMID: 4824345
  130. Characterization of the messenger ribonucleoprotein released from reticulocyte polyribosomes by EDTA treatment.
    Eur J Biochem. 1971 Mar 11;19(2):264-9 PMID: 4994748
  131. Comparative DNA-RNA hybridization in differentiated cells.
    J Mol Biol. 1971 Oct 14;61(1):59-71 PMID: 5004356
  132. The second Sir Hans Krebs Lecture. Informosomes.
    Eur J Biochem. 1969 Aug;10(1):20-35 PMID: 4899460
  133. Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms.
    Science. 1968 Aug 9;161(3841):529-40 PMID: 4874239
  134. Addition of polyadenylate sequences to virus-specific RNA during adenovirus replication.
    Proc Natl Acad Sci U S A. 1971 Nov;68(11):2806-9 PMID: 5315962
  135. Polyadenylic acid sequences in the heterogeneous nuclear RNA and rapidly-labeled polyribosomal RNA of HeLa cells: possible evidence for a precursor relationship.
    Proc Natl Acad Sci U S A. 1971 Jun;68(6):1336-40 PMID: 5288383
  136. A polynucleotide segment rich in adenylic acid in the rapidly-labeled polyribosomal RNA component of mouse sarcoma 180 ascites cells.
    Proc Natl Acad Sci U S A. 1971 Jun;68(6):1331-5 PMID: 5288382
  137. An adenylic acid-rich sequence in messenger RNA of HeLa cells and its possible relationship to reiterated sites in DNA.
    Proc Natl Acad Sci U S A. 1971 Jun;68(6):1321-5 PMID: 5288381
  138. Rapidly labeled, polyribosome-associated RNA having the properties of histone messenger.
    Proc Natl Acad Sci U S A. 1967 Nov;58(5):1977-83 PMID: 5237492
  139. A stabilization of RNA templates in lens cell differentiation.
    Proc Natl Acad Sci U S A. 1967 Jul;58(1):95-102 PMID: 5231622
  140. Initiation of polysome formation in mouse sarcoma 180 ascites cells. Utilization of cytoplasmic messenger ribonucleic acid.
    Biochemistry. 1971 Mar 2;10(5):895-900 PMID: 5544684
Article Info
Journal
The Journal of cell biology
Abbr.
J Cell Biol
ISSN
0021-9525
DOI
10.1083/jcb.64.2.269
Published
1975-02-00
Pages
269-88
Language
English
Region
United States
NLM ID
0375356
PMCID
PMC2109501
Subset
IM
External Links
PubMed source DOI: 10.1083/jcb.64.2.269 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2