Polyadenylic acid sequences in the virion RNA of poliovirus and Eastern Equine Encephalitis virus.

Science (New York, N.Y.) ·Vol. 176 ·No. 4034 ·1972-05-05 ·Pages 526-8

Armstrong JA, Edmonds M, Nakazato H, Phillips BA, Vaughn MH

Abstract

Poliovirus virion RNA contains a single covalently bound sequence of polyadenylic acid which is approximately 49 nucleotides long. A single, slightly longer polyadenylic acid sequence is contained in Eastern Equine Encephalitis virus RNA. Since these viruses are otherwise dissimilar these sequences may play a common role in viral replication, possibly in translation of the viral RNA.

MeSH Terms

Adenine Nucleotides/analysis Animals Base Sequence Cells, Cultured Chickens Cytosine Nucleotides/analysis Electrophoresis, Starch Gel Encephalitis Viruses/analysis Guanine Nucleotides/analysis HeLa Cells/analysis Muscles/cytology Phosphorus Isotopes Poliovirus/analysis Polynucleotides/analysis RNA/analysis RNA, Viral/analysis,isolation & purification,metabolism Ribonucleases/metabolism Tritium Uracil Nucleotides/analysis

Chemicals

Adenine Nucleotides Cytosine Nucleotides Guanine Nucleotides Phosphorus Isotopes Polynucleotides RNA, Viral Uracil Nucleotides Tritium RNA Ribonucleases

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Armstrong J A

Edmonds M

Nakazato H

Phillips B A

Vaughn M H

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.176.4034.526

Published

1972-05-05

Pages

526-8

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.176.4034.526 View journal details

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Polyadenylic acid sequences in the virion RNA of poliovirus and Eastern Equine Encephalitis virus.

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