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PMID: 7696842 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Targeting of proteins to the Golgi apparatus.

Glycoconjugate journal ·Vol. 11 ·No. 5 ·1994-10-00 ·Pages 381-94

Gleeson PA, Teasdale RD, Burke J

Abstract

The Golgi apparatus maintains a highly organized structure in spite of the intense membrane traffic which flows into and out of this organelle. Resident Golgi proteins must have localization signals to ensure that they are targeted to the correct Golgi compartment and not swept further along the secretory pathway. There are a number of distinct groups of Golgi membrane proteins, including glycosyltransferases, recycling trans-Golgi network proteins, peripheral membrane proteins, receptors and viral glycoproteins. Recent studies indicate that there are a number of different Golgi localization signals and mechanisms for retaining proteins to the Golgi apparatus. This review focuses on the current knowledge in this field.

MeSH Terms
Biological Transport Endoplasmic Reticulum/metabolism Glycoproteins/metabolism Golgi Apparatus/metabolism Membrane Proteins/metabolism Viral Proteins/metabolism
Chemicals
Glycoproteins Membrane Proteins Viral Proteins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Gleeson P A
Department of Pathology and Immunology, Monash University Medical School, Alfred Hospital, Melbourne, Victoria, Australia.
Teasdale R D
Burke J
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Article Info
Journal
Glycoconjugate journal
Abbr.
Glycoconj J
ISSN
0282-0080
DOI
10.1007/BF00731273
Published
1994-10-00
Pages
381-94
Language
English
Region
United States
NLM ID
8603310
PMCID
PMC7088089
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00731273 PMC Full Text View journal details
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