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PMID: 1663371 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Endocytosis and signals for internalization.

Current opinion in cell biology ·Vol. 3 ·No. 4 ·1991-08-00 ·Pages 634-41

Trowbridge IS

Abstract

The most important recent advance in the field of endocytosis has been the identification of the internalization signals of several constitutively recycling receptors. Common structural features and chemistry of internalization sequences have been defined, and an exposed tight turn has been implicated as the conformational recognition motif for endocytosis.

MeSH Terms

Amino Acid Sequence Animals Cattle Coated Pits, Cell-Membrane/metabolism Endocytosis Humans Lipoproteins, LDL/metabolism Lysosomes/metabolism Mannosephosphates/metabolism Membrane Glycoproteins/metabolism Molecular Sequence Data Molecular Structure Protein Conformation Receptor, IGF Type 2 Receptors, Cell Surface/metabolism Receptors, LDL/metabolism Receptors, Transferrin/metabolism Signal Transduction Transferrin/metabolism

Chemicals

Lipoproteins, LDL Mannosephosphates Membrane Glycoproteins Receptor, IGF Type 2 Receptors, Cell Surface Receptors, LDL Receptors, Transferrin Transferrin mannose-6-phosphate

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Trowbridge I S

Salk Institute, San Diego, California.

Article Info

Journal

Current opinion in cell biology

Abbr.

Curr Opin Cell Biol

ISSN

0955-0674

DOI

10.1016/0955-0674(91)90034-v

Published

1991-08-00

Pages

634-41

Language

English

Region

England

NLM ID

8913428

Subset

Grants

NCI NIH HHS · CA34787 · United States

Corrections

ErratumIn

External Links

PubMed source DOI: 10.1016/0955-0674(91)90034-v View journal details

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