Alpha-endorphin-like immunoreactivity in plasma cells of the canine colonic mucosa.
During immunocytochemical investigations on the presence of opioid peptides in gastrointestinal endocrine cells it was found that a subpopulation of plasma cells located in the lamina propria of the canine colonic mucosa showed immunoreactivities for alpha-endorphin. All immunohistochemical specificity controls proved the specificity of the reaction. Circumstantial evidence suggest, however, that no authentic alpha-endorphin is present within this cell type. Possibly sequence homologies between alpha-endorphin and the amino acid composition of a certain immunoglobulin are responsible for the immunocytochemically specific alpha-endorphin-like immunoreactivity of plasma cells.
16 references, click to expand
-
Isolation and structure of an untriakontapeptide with opiate activity from camel pituitary glands.Proc Natl Acad Sci U S A. 1976 Apr;73(4):1145-8 PMID: 1063395
-
High-molecular-weight immunoreactive beta-endorphin in extracts of human placenta is a fragment of immunoglobulin G.Science. 1980 Apr 11;208(4440):183-5 PMID: 6244620
-
Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor.Nature. 1979 Mar 29;278(5703):423-7 PMID: 221818
-
A simple method for removing the resin from epoxy-embedded tissue.J Biophys Biochem Cytol. 1961 Apr;9:909-10 PMID: 13768615
-
Analysis of the common precursor to corticotropin and endorphin.J Biol Chem. 1978 Aug 25;253(16):5732-44 PMID: 209048
-
Immunoreactivities of gastrin (G-) cells. I. dilution-dependent staining of G-cells by antisera and non-immune sera.Histochemistry. 1980;65(3):223-37 PMID: 6102969
-
Pancreatic glucagon cells contain endorphin-like immunoreactivity.Histochemistry. 1978 Dec 28;59(1):75-9 PMID: 367989
-
Endorphins: new gut peptides with a familiar face.Gastroenterology. 1979 Nov;77(5):1132-40 PMID: 226450
-
Isolation of peptides with opiate activity from sheep and human pituitaries: relationship to beta-lipotropin.Biochem Biophys Res Commun. 1976 Sep 20;72(2):472-8 PMID: 985493
-
Embedding in epoxy resins for ultrathin sectioning in electron microscopy.Stain Technol. 1960 Nov;35:313-23 PMID: 13741297
-
Molecular evolution of gut hormones: application of comparative studies on the regulation of digestion.Gastroenterology. 1977 Feb;72(2):344-58 PMID: 318627
-
Isolation, primary structure, and synthesis of alpha-endorphin and gamma-endorphin, two peptides of hypothalamic-hypophysial origin with morphinomimetic activity.Proc Natl Acad Sci U S A. 1976 Nov;73(11):3942-6 PMID: 1069261
-
Peptides with a dual function: central neuroregulators and gut hormones.J Physiol (Paris). 1979;75(8):831-50 PMID: 95416
-
Immunoreactivities of gastrin (G-) cells. II. Non-specific binding of immunoglobulins to G-cells by ionic interactions.Histochemistry. 1980;66(2):149-67 PMID: 7390878
-
Complement-mediated unspecific binding of immunoglobulins to some endocrine cells.Histochemistry. 1979 Sep;63(1):15-21 PMID: 389892
-
Corticotropin/beta-endorphin precursor: concomitant storage of its fragments in the secretory granules of anterior pituitary corticotropin/endorphin cells.Life Sci. 1979 Sep 24;25(13):1111-8 PMID: 229369
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