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PMID: 6960226 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Altered genetic code in Paramecium mitochondria: possible evolutionary trends.

Molecular & general genetics : MGG ·Vol. 187 ·No. 2 ·1982-00-00 ·Pages 236-9

Seilhamer JJ, Cummings DJ

Abstract

The sequence and presumptive structure of a tRNA trp gene from Paramecium tetraaurelia are given. The gene is located 1,500 bp downstream from the 13S rRNA gene, in about the middle of the genome. Paramecium tRNA trp has a completely normal TpsiC loop and stem, however its anticodon (UCA) constitutes an alteration in the "universal" genetic code, similar to those seen in fungal and mammalian mitochondria. Most features of Paramecium tRNA trp resemble other mitochondrial counterparts; however, its sequence is more homologous to the "unaltered" tRNA trp (anticodon CCA) from E. coli. Paramecium mitochondria may resemble a primitive stage of organelle evolution.

MeSH Terms
Base Sequence Biological Evolution DNA Mitochondria/ultrastructure Paramecium/genetics RNA, Transfer
Chemicals
DNA RNA, Transfer
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Seilhamer J J
Cummings D J
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27 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00331123
Published
1982-00-00
Pages
236-9
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
Databases
GENBANK
X04175
External Links
PubMed source DOI: 10.1007/BF00331123
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