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PMID: 6370764 Published · ppublish English Journal Article Review

Non-enzymatic glycosylation and the chronic complications of diabetes: an overview.

Diabetologia ·Vol. 26 ·No. 2 ·1984-02-00 ·Pages 93-8

Kennedy L, Baynes JW

Abstract

暂无摘要

MeSH Terms
Adult Animals Blood Proteins/metabolism Child Collagen/metabolism Crystallins/metabolism Diabetes Complications Diabetes Mellitus/blood,metabolism Diabetes Mellitus, Experimental/blood,metabolism Diabetic Nephropathies/etiology,metabolism Diabetic Neuropathies/etiology,metabolism Diabetic Retinopathy/etiology,metabolism Erythrocyte Membrane/metabolism Extracellular Matrix/metabolism Glycated Hemoglobin A/metabolism Guinea Pigs Humans Lipoproteins, HDL/blood,metabolism Lipoproteins, LDL/blood,metabolism Nerve Tissue Proteins/metabolism
Chemicals
Blood Proteins Crystallins Glycated Hemoglobin A Lipoproteins, HDL Lipoproteins, LDL Nerve Tissue Proteins Collagen
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kennedy L
Baynes J W
References (69)
69 references, click to expand
  1. Reduced erythrocyte deformability in diabetes.
    Diabetes. 1978 Sep;27(9):895-901 PMID: 689301
  2. The glycosylation of hemoglobin: relevance to diabetes mellitus.
    Science. 1978 Apr 7;200(4337):21-7 PMID: 635569
  3. Production of pseudodiabetic renal glomerular changes in mice after repeated injections of glucosylated proteins.
    Lancet. 1980 Apr 5;1(8171):738-40 PMID: 6103159
  4. Albumin catabolism in diabetic rats.
    Arch Biochem Biophys. 1983 Aug;225(1):256-62 PMID: 6614922
  5. Effects of age and diabetes mellitus on the solubility and nonenzymatic glucosylation of human skin collagen.
    J Clin Invest. 1981 Jun;67(6):1630-5 PMID: 6787079
  6. The problem of tissue oxygenation in diabetes mellitus. I. Its relation to the early functional changes in the microcirculation of diabetic subjects.
    Acta Med Scand Suppl. 1975;578:49-58 PMID: 239527
  7. Micropinocytic ingestion of glycosylated albumin by isolated microvessels: possible role in pathogenesis of diabetic microangiopathy.
    Proc Natl Acad Sci U S A. 1981 Apr;78(4):2393-7 PMID: 6941299
  8. Nonenzymatic glucosylation of low-density lipoprotein alters its biologic activity.
    Diabetes. 1982 Apr;31(4 Pt 1):283-91 PMID: 6818075
  9. Increased glycosylation of glomerular basement membrane collagen in diabetes.
    Biochem Biophys Res Commun. 1980 Jul 31;95(2):765-9 PMID: 7417290
  10. Albumin deposition in dermal capillary basement membrane in insulin-dependent diabetes mellitus. A preliminary report.
    Diabetes. 1981 Apr;30(4):275-8 PMID: 7009276
  11. Diabetic cataract formation: potential role of glycosylation of lens crystallins.
    Proc Natl Acad Sci U S A. 1978 Jun;75(6):2918-22 PMID: 275862
  12. Blood glucose control and glomerular capillary basement membrane thickening in experimental diabetes.
    Br Med J. 1977 Sep 3;2(6087):605-7 PMID: 901998
  13. Glucosylated and normal human of rat albumin do not bind to renal basement membranes of diabetic and control rats.
    Diabetes. 1983 Apr;32(4):380-2 PMID: 6339308
  14. Quantitation of lysine-bound glucose of normal and diabetic erythrocyte membranes by HPLC analysis of furosine [ epsilon-N(L-furoylmethyl)-L-lysine].
    Biochem Biophys Res Commun. 1981 Apr 15;99(3):1011-9 PMID: 6788041
  15. Role of glycosylation in protein disulfide formation and cataractogenesis.
    Exp Eye Res. 1980 Jul;31(1):9-19 PMID: 7428839
  16. Non-enzymatically glycosylated serum protein in diabetes mellitus: an index of short-term glycaemia.
    Diabetologia. 1981 Aug;21(2):94-8 PMID: 7262478
  17. Structure of hemoglobin AIc: nature of the N-terminal beta chain blocking group.
    Biochem Biophys Res Commun. 1968 Jul 11;32(1):86-93 PMID: 4874776
  18. The thermal stability of collagen in diabetic rats: correlation with severity of diabetes and non-enzymatic glycosylation.
    Diabetologia. 1983 Apr;24(4):282-5 PMID: 6862134
  19. Higher levels of erythrocyte membrane microviscosity in diabetes.
    Diabetes. 1979 Dec;28(12):1138-40 PMID: 510812
  20. Glucosylated albumin and its influence on salicylate binding.
    J Pharm Sci. 1982 Feb;71(2):235-8 PMID: 7062252
  21. Haemoglobin A1: An indicator of the metabolic control of diabetic patients.
    Lancet. 1977 Oct 8;2(8041):734-7 PMID: 71541
  22. An ultrastructural study of chronic sodium cyanate-indiuced neuropathy.
    J Neuropathol Exp Neurol. 1977 Mar-Apr;36(2):352-63 PMID: 190359
  23. Glycosylated hemoglobins and long-term blood glucose control in diabetes mellitus.
    J Clin Endocrinol Metab. 1977 May;44(5):859-64 PMID: 858776
  24. Effect of insulin on human erythrocyte membrane fluidity in diabetes mellitus.
    Diabetologia. 1983 May;24(5):311-3 PMID: 6347778
  25. Reducible components in the proteins of human erythrocyte membrane.
    Biochim Biophys Acta. 1976 May 20;434(1):51-7 PMID: 938671
  26. Role of nonenzymatic glycosylation in experimental cataract formation.
    Biochem Biophys Res Commun. 1980 Jul 31;95(2):894-901 PMID: 7417294
  27. Increased concentration of albumin in kidney basement membranes in diabetes mellitus.
    Diabetes. 1981 Oct;30(10):843-6 PMID: 7274588
  28. The milieu interieur and the islets of Langerhans.
    Diabetologia. 1981;20(1):1-11 PMID: 7009282
  29. Nonenzymatic glycosylation of low density lipoproteins in vitro. Effects on cell-interactive properties.
    Diabetes. 1981 Oct;30(10):875-8 PMID: 7274589
  30. Oxygen affinity of haemoglobin and red cell 2,3-diphosphoglycerate in childhood diabetes.
    Acta Paediatr Scand. 1975 Mar;64(2):355-61 PMID: 1130194
  31. Specific quantitation by HPLC of protein (lysine) bound glucose in human serum albumin and other glycosylated proteins.
    J Clin Chem Clin Biochem. 1981 Feb;19(2):81-7 PMID: 6783732
  32. Glycosylated haemoglobins and the oxygen affinity of whole blood.
    Diabetologia. 1982 Nov;23(5):399-402 PMID: 6816650
  33. Glycosylated collagen.
    Biochem Biophys Res Commun. 1979 Nov 28;91(2):498-501 PMID: 518648
  34. Glucosylation of human collagen in aging and diabetes mellitus.
    J Clin Invest. 1980 Nov;66(5):1179-81 PMID: 7430347
  35. In vitro synthesis of hemoglobin AIc.
    FEBS Lett. 1976 Dec 1;71(2):356-60 PMID: 12012
  36. Hyperglycemia, polyol metabolism, and complications of diabetes mellitus.
    Annu Rev Med. 1975;26:521-36 PMID: 238458
  37. Nonenzymatic glucosylation of high-density lipoprotein accelerates its catabolism in guinea pigs.
    Diabetes. 1982 Nov;31(11):1029-32 PMID: 6816643
  38. Nonenzymatic glycosylation of peripheral nerve protein in diabetes mellitus.
    Proc Natl Acad Sci U S A. 1981 Aug;78(8):5190-2 PMID: 6946466
  39. Non-enzymatic glycosylation of human serum lipoproteins. Elevated epsilon-lysine glycosylated low density lipoprotein in diabetic patients.
    FEBS Lett. 1981 Jun 29;129(1):1-4 PMID: 7274460
  40. Nonenzymatically glycosylated serum protein: spurious elevation due to free glucose in serum.
    Diabetes. 1980 May;29(5):413-5 PMID: 7380111
  41. Reduced susceptibility of nonenzymatically glucosylated glomerular basement membrane to proteases: is thickening of diabetic glomerular basement membranes due to reduced proteolytic degradation?
    Ren Physiol. 1980;3(1-6):4-8 PMID: 7034096
  42. Structural and functional consequences of increased tubulin glycosylation in diabetes mellitus.
    Proc Natl Acad Sci U S A. 1982 Nov;79(21):6546-50 PMID: 6959136
  43. Increased glycosylation of proteins from cataractous lenses in diabetes.
    Diabetologia. 1983 Jul;25(1):36-8 PMID: 6884614
  44. Nonenzymatic glycosylation of erythrocyte membrane proteins. Relevance to diabetes.
    J Clin Invest. 1980 Apr;65(4):896-901 PMID: 7358849
  45. Excessive nonenzymatic glycosylation of peripheral and central nervous system myelin components in diabetic rats.
    Diabetes. 1983 Jul;32(7):670-4 PMID: 6862112
  46. Structural heterogeneity of human hemoglobin A due to nonenzymatic glycosylation.
    J Biol Chem. 1979 May 25;254(10):3892-8 PMID: 438166
  47. Are the binding and degradation of low density lipoprotein altered in Type 2 (non-insulin-dependent) diabetes mellitus?
    Diabetologia. 1982 Jul;23(1):28-33 PMID: 7117726
  48. Distribution of salicylate in lens and intraocular fluids and its effect on cataract formation.
    Am J Med. 1983 Jun 14;74(6A):83-90 PMID: 6859071
  49. Haemoglobin AIc concentrations after initial insulin treatment for newly discovered diabetes.
    Br Med J. 1978 Mar 25;1(6115):741-2 PMID: 630325
  50. HbAlc--an indicator of diabetic control.
    J Pediatr. 1978 Jul;93(1):13-6 PMID: 650324
  51. Impaired erythrocyte doublet formation in diabetes.
    Diabetologia. 1981 Dec;21(6):575-8 PMID: 7338294
  52. Changes in lung lysyl oxidase activity in streptozotocin-diabetes and in starvation.
    Biochim Biophys Acta. 1979 Jul 18;585(4):481-7 PMID: 37920
  53. Increased collagen cross-linkages in experimental diabetes: reversal by beta-aminopropionitrile and D-penicillamine.
    Diabetes. 1980 Oct;29(10):778-81 PMID: 7439537
  54. Nonenzymatic glucosylation of rat albumin. Studies in vitro and in vivo.
    J Biol Chem. 1979 Oct 10;254(19):9394-400 PMID: 489542
  55. The biosynthesis of human hemoglobin A1c. Slow glycosylation of hemoglobin in vivo.
    J Clin Invest. 1976 Jun;57(6):1652-9 PMID: 932199
  56. Functional properties of the glycosylated minor components of human adult hemoglobin.
    J Biol Chem. 1979 Feb 10;254(3):702-7 PMID: 33173
  57. Nonenzymatic glucosylation and glucose-dependent cross-linking of protein.
    J Biol Chem. 1983 Aug 10;258(15):9406-12 PMID: 6409904
  58. Characterization of glycosylated hemoglobins. Relevance to monitoring of diabetic control and analysis of other proteins.
    J Clin Invest. 1983 May;71(5):1062-72 PMID: 6406542
  59. Nonenzymatic glycosylation, sulfhydryl oxidation, and aggregation of lens proteins in experimental sugar cataracts.
    J Exp Med. 1979 Nov 1;150(5):1098-107 PMID: 501285
  60. Nonenzymatic glucosylation of serum proteins in diabetes mellitus.
    Diabetes. 1979 Nov;28(11):1011-4 PMID: 488539
  61. Limited joint mobility in Type I diabetes mellitus.
    Postgrad Med J. 1982 Aug;58(682):481-4 PMID: 7134086
  62. Limited joint mobility in childhood diabetes mellitus indicates increased risk for microvascular disease.
    N Engl J Med. 1981 Jul 23;305(4):191-4 PMID: 7242598
  63. Comparison of a colorimetric assay for glycosylated hemoglobin with ion-exchange chromatography.
    Diabetes. 1979 Dec;28(12):1120-5 PMID: 510809
  64. A new N-terminal blocking group involving a Schiff base in hemoglobin AIc.
    Biochemistry. 1966 Aug;5(8):2489-503 PMID: 5968556
  65. Chemical quantitation of hemoglobin glycosylation: fluorometric detection of formaldehyde released upon periodate oxidation of glycoglobin.
    Anal Biochem. 1981 Nov 1;117(2):427-32 PMID: 6275744
  66. Correlation of glucose regulation and hemoglobin AIc in diabetes mellitus.
    N Engl J Med. 1976 Aug 19;295(8):417-20 PMID: 934240
  67. Minor hemoglobins, diabetic "control", and diseases of postsynthetic protein modification.
    Ann Intern Med. 1977 Oct;87(4):489-91 PMID: 907248
  68. Insulin, diabetes, and the cell membrane: an hypothesis.
    Diabetologia. 1983 May;24(5):308-10 PMID: 6347777
  69. Different behaviour of haemoglobin A1a-c and glycosyl-albumin levels during recovery from diabetic ketoacidosis and non-acidotic coma.
    Diabetologia. 1981 Sep;21(3):211-5 PMID: 6795076
Article Info
Journal
Diabetologia
Abbr.
Diabetologia
ISSN
0012-186X
DOI
10.1007/BF00281113
Published
1984-02-00
Pages
93-8
Language
English
Region
Germany
NLM ID
0006777
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00281113 View journal details
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