Home LiteratureArticle Details
PMID: 6179472 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Expression of recA-gene dependent SOS functions in Salmonella typhimurium.

Antonie van Leeuwenhoek ·Vol. 48 ·No. 2 ·1982-05-00 ·Pages 159-67

Guerrero R, Barbé J

Abstract

Thymine starvation of RecA+ Thy- strains of Salmonella typhimurium does not induce the inhibition of cellular respiration, one of the recA-gene dependent SOS functions. Nevertheless, thymine deprivation is able to produce a normal induction of prophage and thymineless death in these same strains However, when these mutants are treated, in the presence of thymine, with UV-irradiation or bleomycin, they show a normal inhibition of cellular respiration and other SOS functions. Thus, one injurious treatment (thymine deprivation) may trigger prophage induction but not cessation of respiration, whereas another agent (UV-irradiation) may induce both. Together, these results suggest a possible discrimination in the pathways and conditions of expression of various SOS functions.

MeSH Terms
Bleomycin/pharmacology Culture Media Gene Expression Regulation/drug effects,radiation effects Oxygen Consumption/drug effects,radiation effects Salmonella typhimurium/drug effects,genetics,metabolism Thymine Ultraviolet Rays/adverse effects
Chemicals
Culture Media Bleomycin Thymine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Guerrero R
Barbé J
References (16)
16 references, click to expand
  1. UV sensitivity of a nonrepressor regulatory protein of bacteriophage P22.
    J Virol. 1976 Apr;18(1):65-70 PMID: 768525
  2. Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli.
    Bacteriol Rev. 1976 Dec;40(4):869-907 PMID: 795416
  3. Production of cells without deoxyribonucleic acid during thymidine starvation of lexA- cultures of Escherichia coli K-12.
    J Bacteriol. 1975 Dec;124(3):1113-21 PMID: 1104571
  4. Model for regulation of Escherichia coli DNA repair functions.
    Proc Natl Acad Sci U S A. 1975 Jun;72(6):2330-4 PMID: 1094463
  5. Identification and radiochemical purification of the recA protein of Escherichia coli K-12.
    Proc Natl Acad Sci U S A. 1976 Nov;73(11):3979-83 PMID: 792880
  6. DNA repair in Proteus mirabilis. IV. Post-irradiation DNA degradation as influenced by a function inducible in rec+ cells.
    Mol Gen Genet. 1977 Jul 7;154(1):35-41 PMID: 331077
  7. Evidence relating cessation of respiration, cell envelope changes, and death in ultraviolet-irradiated Escherichia coli B-r cells.
    J Bacteriol. 1974 Feb;117(2):551-9 PMID: 4590476
  8. Molecular events and molecules that lead to induction of prophage and SOS functions.
    Cold Spring Harb Symp Quant Biol. 1979;43 Pt 2:897-907 PMID: 385234
  9. Protein X is the product of the recA gene of Escherichia coli.
    Proc Natl Acad Sci U S A. 1977 Dec;74(12):5275-9 PMID: 341151
  10. DNA repair in Bacillus subtilis. I. The presence of an inducible system.
    Mol Gen Genet. 1977 Jun 8;153(2):211-8 PMID: 407445
  11. Respiration, growth and viability of repair-deficient mutants of Escherichia coli after ultraviolet irradiation.
    Int J Radiat Biol Relat Stud Phys Chem Med. 1974 Jan;25(1):51-60 PMID: 4588877
  12. Thermal enhancement of ultraviolet mutability in a tif-1 uvrA derivative of Escherichia coli B-r: evidence that ultraviolet mutagenesis depends upon an inducible function.
    Proc Natl Acad Sci U S A. 1974 May;71(5):1930-4 PMID: 4600265
  13. Effects of antipain (a protease inhibitor) on respiration, viability, and excision of pyrimidine dimers in UV-irradiated Escherichia coli cells.
    J Bacteriol. 1978 Sep;135(3):1167-70 PMID: 211114
  14. Mutagenesis of ultraviolet-irradiated lambda phage by host cell irradiation: induction of Weigle mutagenesis is not an all-or-none process.
    Mol Gen Genet. 1980 Jan;177(2):207-11 PMID: 6445034
  15. Regulation of cessation of respiration and killing by cyclic 3',5'-adenosine monophosphate and its receptor protein after far-ultraviolet irradiation of Escherichia coli.
    Mol Gen Genet. 1978 Feb 16;159(2):125-30 PMID: 204860
  16. Escherichia coli recA gene product inactivates phage lambda repressor.
    Proc Natl Acad Sci U S A. 1978 Oct;75(10):4714-8 PMID: 368796
Article Info
Journal
Antonie van Leeuwenhoek
Abbr.
Antonie Van Leeuwenhoek
ISSN
0003-6072
DOI
10.1007/BF00405200
Published
1982-05-00
Pages
159-67
Language
English
Region
Netherlands
NLM ID
0372625
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00405200 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2