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PMID: 768525 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

UV sensitivity of a nonrepressor regulatory protein of bacteriophage P22.

Journal of virology ·Vol. 18 ·No. 1 ·1976-04-00 ·Pages 65-70

Tokuno SI, Gough M

Abstract

The product of phage P22 gene c1 has two functions: it promotes synthesis of P22 repressor and it retards expression of some lytic genes. We present evidence that this product is inactivated in UV-irradiated hosts. The conditions for inactivation of c1 product include a functional DNA recombination system involving the host recA gene.

MeSH Terms
Bacterial Proteins/radiation effects DNA, Viral/biosynthesis Genes Genes, Regulator Mutation Radiation Effects Salmonella Phages/growth & development,metabolism,radiation effects Salmonella typhimurium/radiation effects Ultraviolet Rays Virus Replication
Chemicals
Bacterial Proteins DNA, Viral
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Tokuno S I
Gough M
References (20)
20 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.18.1.65-70.1976
Published
1976-04-00
Pages
65-70
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC515522
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.18.1.65-70.1976 PMC Full Text View journal details
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