Futile xylitol cycle in Lactobacillus casei.
A futile xylitol cycle appears to be responsible for xylitol-mediated inhibition of growth of Lactobacillus casei Cl-16 at the expense of ribitol. The gratuitously induced xylitol-specific phosphoenolpyruvate-dependent phosphotransferase accumulates the pentitol as xylitol-5-phosphate, a phosphatase cleaves the latter, and an export system expels the xylitol. Operation of the cycle rapidly dissipates the ribitol-5-phosphate pool (and ultimately the energy supply of the cell), thereby producing bacteriostasis.
17 references, click to expand
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Novel phosphoenolpyruvate-dependent futile cycle in Streptococcus lactis: 2-deoxy-D-glucose uncouples energy production from growth.J Bacteriol. 1982 Sep;151(3):1454-65 PMID: 6286601
-
Regulation of lactose-phosphoenolpyruvate-dependent phosphotransferase system and beta-D-phosphogalactoside galactohydrolase activities in Lactobacillus casei.J Bacteriol. 1983 Jun;154(3):1195-203 PMID: 6406426
-
Regulation and characterization of the galactose-phosphoenolpyruvate-dependent phosphotransferase system in Lactobacillus casei.J Bacteriol. 1983 Jun;154(3):1204-14 PMID: 6406427
-
Involvement of lactose enzyme II of the phosphotransferase system in rapid expulsion of free galactosides from Streptococcus pyogenes.J Bacteriol. 1983 Oct;156(1):236-42 PMID: 6413489
-
Mechanism of inducer expulsion in Streptococcus pyogenes: a two-step process activated by ATP.J Bacteriol. 1983 Oct;156(1):354-61 PMID: 6225770
-
Intracellular hexose-6-phosphate:phosphohydrolase from Streptococcus lactis: purification, properties, and function.J Bacteriol. 1983 Oct;156(1):70-80 PMID: 6311807
-
Purification and characterization of the IIIXtl phospho-carrier protein of the phosphoenolpyruvate-dependent xylitol:phosphotransferase found in Lactobacillus casei C183.J Bacteriol. 1983 Nov;156(2):611-9 PMID: 6415035
-
Colorimetric determination of orthophosphate in the assay of inorganic pyrophosphatase activity.Anal Biochem. 1972 Sep;49(1):37-47 PMID: 5081106
-
Aldolase of lactic acid bacteria: a case history in the use of an enzyme as an evolutionary marker.Bacteriol Rev. 1973 Dec;37(4):453-78 PMID: 4203394
-
In vivo regulation of glycolysis and characterization of sugar: phosphotransferase systems in Streptococcus lactis.J Bacteriol. 1978 Nov;136(2):465-76 PMID: 101523
-
Pentitol metabolism in Lactobacillus casei.J Bacteriol. 1979 Dec;140(3):949-54 PMID: 118163
-
Regulation of beta-galactoside phosphate accumulation in Streptococcus pyogenes by an expulsion mechanism.Proc Natl Acad Sci U S A. 1980 Sep;77(9):5497-501 PMID: 7001481
-
Regulation of methyl-beta-d-thiogalactopyranoside-6-phosphate accumulation in Streptococcus lactis by exclusion and expulsion mechanisms.J Bacteriol. 1981 Jun;146(3):885-94 PMID: 6787017
-
Xylitol-mediated transient inhibition of ribitol utilization by Lactobacillus casei.J Bacteriol. 1982 May;150(2):657-61 PMID: 6802797
-
Use of 31P nuclear magnetic resonance spectroscopy and 14C fluorography in studies of glycolysis and regulation of pyruvate kinase in Streptococcus lactis.J Bacteriol. 1984 Jun;158(3):791-800 PMID: 6427193
-
Phosphoenolpyruvate and 2-phosphoglycerate: endogenous energy source(s) for sugar accumulation by starved cells of Streptococcus lactis.J Bacteriol. 1977 May;130(2):583-95 PMID: 122509
-
QUANTITATIVE STUDIES ON GLYCOLYTIC ENZYMES IN LACTOBACILLUS PLANTARUM. I. CONCENTRATION OF INORGANIC IONS AND COENZYMES IN FERMENTING CELLS.J Bacteriol. 1963 Dec;86:1295-300 PMID: 14086104
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