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PMID: 3515317 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Nucleotide sequence of the CytR regulatory gene of E. coli K-12.

Nucleic acids research ·Vol. 14 ·No. 5 ·1986-03-11 ·Pages 2215-28

Valentin-Hansen P, Larsen JE, Højrup P, Short SA, Barbier CS

Abstract

We have determined the nucleotide sequence of the cytR gene, which codes for the Cyt repressor (CytR). The coding region consists of 1023 or 1029 bp. The subunits of CytR are thus predicted to consist of 341 or 343 residues. It is shown that the N-terminal segment of the polypeptide is structurally similar to the DNA-binding region of known DNA-binding proteins. In addition, there exists an exceptionally high amino acid sequence homology between CytR and the Gal repressor, indicating a common origin of evolution.

MeSH Terms

Amino Acid Sequence Bacterial Proteins/genetics Base Sequence Cloning, Molecular Codon DNA-Binding Proteins/genetics Escherichia coli/genetics Escherichia coli Proteins Promoter Regions, Genetic Receptors, Cyclic AMP/metabolism Repressor Proteins/genetics Transcription Factors/genetics

Chemicals

Bacterial Proteins Codon CytR protein, E coli DNA-Binding Proteins Escherichia coli Proteins Receptors, Cyclic AMP Repressor Proteins Transcription Factors

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Valentin-Hansen P

Larsen J E

Højrup P

Short S A

Barbier C S

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27 references, click to expand

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Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/14.5.2215

Published

1986-03-11

Pages

2215-28

Language

English

Region

England

NLM ID

0411011

PMCID

PMC339653

Subset

Databases

GENBANK

X03683

External Links

PubMed source DOI: 10.1093/nar/14.5.2215 PMC Full Text View journal details

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Nucleotide sequence of the CytR regulatory gene of E. coli K-12.

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