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PMID: 2906814 Published · ppublish English Journal Article Review

Pertussis: the disease and new diagnostic methods.

Clinical microbiology reviews ·Vol. 1 ·No. 4 ·1988-10-00 ·Pages 365-76

Friedman RL

Abstract

Bordetella pertussis, the causative agent of whooping cough, produces an acute and chronic respiratory infection in infants and young children. B. pertussis is still a major health problem of young children throughout the world even though effective immunization against whooping cough is available. While predominantly a childhood disease, it has been reported also to be a cause of persistent cough in adults. This review discusses the numerous bacterial virulence factors that may play roles in the pathogenesis of pertussis and in immunity to infection. The present problems with pertussis diagnosis, recent advances, and future prospects for new and improved rapid diagnostics tests also are explored.

MeSH Terms
Bordetella pertussis/pathogenicity Humans Virulence Factors, Bordetella/analysis Whooping Cough/diagnosis
Chemicals
Virulence Factors, Bordetella
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Friedman R L
Department of Microbiology and Immunology, College of Medicine, University of Arizona, Tucson 85724.
References (154)
154 references, click to expand
  1. Pertussis in Sweden after the cessation of general immunization in 1979.
    Pediatr Infect Dis J. 1987 Apr;6(4):364-71 PMID: 3588110
  2. The invasive adenylate cyclase of Bordetella pertussis. Properties and penetration kinetics.
    Biochem J. 1987 Apr 1;243(1):145-51 PMID: 2886119
  3. Major fragment of soluble peptidoglycan released from growing Bordetella pertussis is tracheal cytotoxin.
    Infect Immun. 1987 Sep;55(9):2117-20 PMID: 2887513
  4. Efficacy of enzyme-linked immunosorbent assay for rapid diagnosis of Bordetella pertussis infection.
    J Clin Microbiol. 1987 Nov;25(11):2102-4 PMID: 2891724
  5. Diagnostic deoxyribonucleic acid probes for infectious diseases.
    Clin Microbiol Rev. 1988 Jan;1(1):82-101 PMID: 3060247
  6. The role of antibiotics, immunizations, and adenoviruses in pertussis.
    Pediatrics. 1978 Feb;61(2):224-30 PMID: 204899
  7. The changing epidemiology of pertussis in young infants. The role of adults as reservoirs of infection.
    Am J Dis Child. 1978 Apr;132(4):371-3 PMID: 645653
  8. Comparison of the histamine hypersensitivity and the Limulus amoebocyte lysate tests for endotoxin activity.
    Infect Immun. 1978 Oct;22(1):292-4 PMID: 365749
  9. Enzyme-linked immunosorbent assay for detection and quantitation of capsular antigen of Haemophilus influenzae type b.
    Infect Immun. 1978 Nov;22(2):617-9 PMID: 310425
  10. Pertussis in a rural area of Kenya: epidemiology and a preliminary report on a vaccine trial.
    Bull World Health Organ. 1978;56(5):773-80 PMID: 310719
  11. Detection of respiratory syncytial virus in nasal secretions from infants by enzyme-linked immunosorbent assay.
    J Infect Dis. 1979 Apr;139(4):483-6 PMID: 374650
  12. Release of soluble peptidoglycan from growing gonococci: hexaminidase and amidase activities.
    Infect Immun. 1979 Jun;24(3):869-78 PMID: 112060
  13. Polymorphonuclear leukocyte-inhibitory factor of Bordetella pertussis. I. Extraction and partial purification of phagocytosis- and chemotaxis-inhibitory activities.
    Biken J. 1978 Dec;21(4):121-35 PMID: 224858
  14. Selective primary health care: an interim strategy for disease control in developing countries.
    N Engl J Med. 1979 Nov 1;301(18):967-74 PMID: 114830
  15. Intracellular localization of the dermonecrotic toxin of Bordetella pertussis.
    Infect Immun. 1979 Sep;25(3):896-901 PMID: 227787
  16. Biological activities of fragments derived from Bordetella pertussis endotoxin: isolation of a nontoxic, Shwartzman-negative lipid A possessing high adjuvant properties.
    Infect Immun. 1980 Mar;27(3):739-45 PMID: 6247278
  17. Selective isolation and culture of a proliferating epithelial cell population from the hamster trachea.
    In Vitro. 1980 Apr;16(4):313-9 PMID: 6772544
  18. Isolation of two protein-free and chemically different lipopolysaccharides from Bordetella pertussis phenol-extracted endotoxin.
    J Bacteriol. 1980 Jul;143(1):78-88 PMID: 6249793
  19. Release of soluble peptidoglycan from growing conococci: demonstration of anhydro-muramyl-containing fragments.
    Infect Immun. 1980 Sep;29(3):914-25 PMID: 6776063
  20. Calmodulin activates prokaryotic adenylate cyclase.
    Proc Natl Acad Sci U S A. 1980 Jul;77(7):3841-4 PMID: 6253992
  21. The IgM and IgG response to Bordetella pertussis vaccination and infection.
    J Med Microbiol. 1981 Feb;14(1):1-7 PMID: 6257906
  22. Enzyme-linked immunosorbent assay for detection of pertussis immunoglobulin A in nasopharyngeal secretions as an indicator of recent infection.
    J Clin Microbiol. 1981 Feb;13(2):286-92 PMID: 6259201
  23. Biology of Bordetella bronchiseptica.
    Microbiol Rev. 1980 Dec;44(4):722-38 PMID: 7010115
  24. A role of the B-oligomer moiety of islet-activating protein, pertussis toxin, in development of the biological effects on intact cells.
    J Biol Chem. 1983 Jun 10;258(11):6756-61 PMID: 6343381
  25. Bordetella pertussis toxins.
    Pharmacol Ther. 1982;19(1):1-53 PMID: 6304790
  26. Separation and purification of the hemagglutinins from Bordetella pertussis.
    Infect Immun. 1983 Jul;41(1):313-20 PMID: 6305841
  27. Diagnosis of whooping cough: comparison of serological tests with isolation of Bordetella pertussis. A combined Scottish study.
    Br Med J. 1970 Dec 12;4(5736):637-9 PMID: 4321207
  28. Whooping cough is first described as a disease sui generis by Baillou in 1640.
    Pediatrics. 1970 Oct;46(4):522 PMID: 4926561
  29. Agglutinin response to pertussis vaccine. I. Effect of dosage and interval.
    J Pediatr. 1971 Aug;79(2):197-202 PMID: 5560043
  30. Detection of Bordetella pertussis antibodies in human sera by complement-fixation and immunofluorescence.
    J Hyg (Lond). 1972 Mar;70(1):75-83 PMID: 4335341
  31. Selective medium for the isolation of bordetella pertussis and parapertussis.
    J Clin Pathol. 1972 Aug;25(8):732-3 PMID: 4342612
  32. Steroids in treatment of pertussis. A controlled clinical trial.
    Arch Dis Child. 1973 Jan;48(1):51-4 PMID: 4568265
  33. Activation of thyroid membrane adenylate cyclase by purine nucleotides.
    J Biol Chem. 1973 Jan 10;248(1):350-5 PMID: 4692839
  34. On the aetiology of whooping cough.
    J Hyg (Lond). 1973 Mar;71(1):139-44 PMID: 4348453
  35. Pertussis antibodies in the sera of children exposed to Bordetella pertussis by vaccination or infection.
    J Hyg (Lond). 1973 Mar;71(1):193-207 PMID: 4348456
  36. Bactericidal antibody in serum during infection with Bordetalla pertussis.
    J Infect Dis. 1973 Oct;128(4):555-8 PMID: 4355209
  37. Modulation of inflammation and immunity by cyclic AMP.
    Science. 1974 Apr 5;184(4132):19-28 PMID: 4131281
  38. Cyclic AMP and the immune response;.
    Adv Cyclic Nucleotide Res. 1974;4(0):1-79 PMID: 4368552
  39. Pertussis: persistent problems.
    J Pediatr. 1974 Oct;85(4):589-91 PMID: 4374520
  40. Pertussis.
    Medicine (Baltimore). 1975 Nov;54(6):427-69 PMID: 1186491
  41. Isolation and properties of the leukocytosis- and lymphocytosis-promoting factor of Bordetella pertussis.
    J Exp Med. 1976 Jun 1;143(6):1483-502 PMID: 58054
  42. Extracytoplasmic adenylate cyclase of Bordetella pertussis.
    Proc Natl Acad Sci U S A. 1976 Jun;73(6):1926-30 PMID: 180529
  43. Soluble adenylate cyclase from the culture medium of Bordetella pertussis: purification and characterization.
    J Bacteriol. 1976 Aug;127(2):890-8 PMID: 182669
  44. Separation and characterization of two distinct hemagglutinins contained in purified leukocytosis-promoting factor from Bordetella pertussis.
    Biochim Biophys Acta. 1976 Oct 22;444(3):765-82 PMID: 186106
  45. The beta-adrenergic receptors in pertussis.
    J Trop Med Hyg. 1976 Oct;79(10):213-7 PMID: 189057
  46. Pertussis in the adult.
    Annu Rev Med. 1977;28:179-85 PMID: 324357
  47. Identification of 2-methyl-3-hydroxydecanoic and 2-methyl-3-hydroxytetradecanoic acids in the 'lipid X' fraction of the Bordetella pertussis endotoxin.
    Eur J Biochem. 1977 Aug 1;77(3):535-44 PMID: 196857
  48. Enrichment medium for the isolation of Bordetella.
    J Clin Microbiol. 1977 Sep;6(3):303-9 PMID: 198430
  49. Detection of antibodies in human serum against the fimbrial haemagglutinin of Bordetella pertussis by enzyme-linked immunosorbent assay.
    J Med Microbiol. 1982 Feb;15(1):85-96 PMID: 6292429
  50. Subunit structure of islet-activating protein, pertussis toxin, in conformity with the A-B model.
    Biochemistry. 1982 Oct 26;21(22):5516-22 PMID: 6293544
  51. Cephalexin-supplemented Jones-Kendrick charcoal agar for selective isolation of Bordetella pertussis: comparison with previously described media.
    J Clin Microbiol. 1983 Jan;17(1):60-2 PMID: 6298274
  52. Serologic diagnosis of pertussis: comparison of enzyme-linked immunosorbent assay and bacterial agglutination.
    J Infect Dis. 1983 Feb;147(2):252-7 PMID: 6298315
  53. Enzyme-linked immunosorbent assay and radioimmunoassay in the serologic diagnosis of infectious diseases.
    J Infect Dis. 1983 Feb;147(2):258-63 PMID: 6338130
  54. Comparison of washed nasopharyngeal cells and whole nasal secretions for detection of respiratory syncytial virus antigens by enzyme-linked immunosorbent assay.
    J Clin Microbiol. 1986 Feb;23(2):383-4 PMID: 3700621
  55. Pertussis toxin gene: nucleotide sequence and genetic organization.
    Science. 1986 Jun 6;232(4755):1258-64 PMID: 3704651
  56. Bordetella pertussis tracheal cytotoxin.
    Dev Biol Stand. 1985;61:103-11 PMID: 2872096
  57. Heptakis(2,6-O-dimethyl)beta-cyclodextrin: a novel growth stimulant for Bordetella pertussis phase I.
    J Clin Microbiol. 1983 May;17(5):781-6 PMID: 6306047
  58. Rapid and sensitive colorimetric method for visualizing biotin-labeled DNA probes hybridized to DNA or RNA immobilized on nitrocellulose: Bio-blots.
    Proc Natl Acad Sci U S A. 1983 Jul;80(13):4045-9 PMID: 6191328
  59. Serological response to filamentous hemagglutinin and lymphocytosis-promoting toxin of Bordetella pertussis.
    Infect Immun. 1983 Sep;41(3):1150-6 PMID: 6309662
  60. Tn5-induced mutations affecting virulence factors of Bordetella pertussis.
    Infect Immun. 1983 Oct;42(1):33-41 PMID: 6311749
  61. DNA hybridization technique for the detection of Neisseria gonorrhoeae in men with urethritis.
    J Infect Dis. 1983 Sep;148(3):462-71 PMID: 6413595
  62. Heterogeneity of the filamentous haemagglutinin of Bordetella pertussis studied with monoclonal antibodies.
    J Gen Microbiol. 1983 Sep;129(9):2769-78 PMID: 6313862
  63. Pertussis toxin. Affinity purification of a new ADP-ribosyltransferase.
    J Biol Chem. 1983 Dec 10;258(23):14647-51 PMID: 6315733
  64. Serum IgA antibody to Bordetella pertussis as an indicator of infection.
    J Med Microbiol. 1983 Nov;16(4):417-26 PMID: 6315942
  65. Development of a pertussis component vaccine in Japan.
    Lancet. 1984 Jan 21;1(8369):122-6 PMID: 6140441
  66. Production and properties of Bordetella pertussis heat-labile toxin.
    J Med Microbiol. 1984 Feb;17(1):91-103 PMID: 6319705
  67. G proteins and dual control of adenylate cyclase.
    Cell. 1984 Mar;36(3):577-9 PMID: 6321035
  68. The epidemiology of pertussis and pertussis immunization in the United Kingdom and the United States: a comparative study.
    Curr Probl Pediatr. 1984 Feb;14(2):1-78 PMID: 6368134
  69. Ability of monomeric peptidoglycan fragments from Neisseria gonorrhoeae to damage human fallopian-tube mucosa.
    J Infect Dis. 1984 Mar;149(3):378-86 PMID: 6425421
  70. Diagnosis of pertussis.
    J Infect. 1984 Mar;8(2):149-56 PMID: 6327829
  71. Structure of the terminal reducing heptasaccharide of polysaccharide 1 isolated from the Bordetella pertussis endotoxin.
    J Bacteriol. 1984 Aug;159(2):611-7 PMID: 6086579
  72. Counterimmunoelectrophoresis in the diagnosis of whooping cough.
    J Clin Pathol. 1984 Aug;37(8):950-1 PMID: 6088591
  73. Pertussis toxin and extracytoplasmic adenylate cyclase as virulence factors of Bordetella pertussis.
    J Infect Dis. 1984 Aug;150(2):219-22 PMID: 6088647
  74. Characterization of antibody inhibiting adherence of Bordetella pertussis to human respiratory epithelial cells.
    J Clin Microbiol. 1984 Aug;20(2):167-70 PMID: 6092416
  75. EPIDEMIOLOGY OF A SMALL PERTUSSIS OUTBREAK IN KENT COUNTY, MICHIGAN.
    Public Health Rep. 1965 Apr;80:365-9 PMID: 14279983
  76. Antigens of Bordetella pertussis. I. Activities of cell walls and protoplasm.
    J Immunol. 1959 Nov;83:496-501 PMID: 14425265
  77. WHOOPING-COUGH: DIFFICULTIES IN DIAGNOSIS AND INEFFECTIVENESS OF IMMUNIZATION.
    Br Med J. 1965 Sep 11;2(5462):623-6 PMID: 14331622
  78. Chronic pulmonary infection in childhood.
    Practitioner. 1965 Dec;195(170):749-54 PMID: 5847219
  79. The laboratory diagnosis of whooping cough by fluorescent antibody and by culture methods.
    Can Med Assoc J. 1966 Aug 6;95(6):263-6 PMID: 4288082
  80. Comparison of specimen transport systems for Bordetella pertussis.
    Eur J Clin Microbiol. 1986 Dec;5(6):671-3 PMID: 2879732
  81. Nucleotide sequence homology to pertussis toxin gene in Bordetella bronchiseptica and Bordetella parapertussis.
    Infect Immun. 1987 Mar;55(3):497-501 PMID: 3818081
  82. Purification and characterization of serotype 6 fimbriae from Bordetella pertussis and comparison of their properties with serotype 2 fimbriae.
    Infect Immun. 1987 Apr;55(4):916-22 PMID: 2881893
  83. Expression and immunological properties of the five subunits of pertussis toxin.
    Infect Immun. 1987 Apr;55(4):963-7 PMID: 3549567
  84. Mechanisms of bacterial pathogenicity that involve production of calmodulin-sensitive adenylate cyclases.
    Microbiol Rev. 1987 Mar;51(1):60-5 PMID: 2882409
  85. Laboratory diagnosis of pertussis: the state of the art.
    Pediatr Infect Dis J. 1987 Feb;6(2):145-51 PMID: 2882465
  86. Immune response to the B oligomer of pertussis toxin.
    Infect Immun. 1987 May;55(5):1132-6 PMID: 3570457
  87. Cross-reactions in Legionella antisera with Bordetella pertussis strains.
    J Clin Microbiol. 1987 Apr;25(4):594-6 PMID: 2883198
  88. Bordetella pertussis infection: a cause of persistent cough in adults.
    Med J Aust. 1987 May 18;146(10):522-5 PMID: 3574177
  89. Alteration of intracellular cAMP levels and beating rates of cultured chick cardiac cells by Bordetella pertussis adenylate cyclase.
    Mol Pharmacol. 1987 May;31(5):529-34 PMID: 2883570
  90. Comparison of nasopharyngeal aspirate and nasopharyngeal swab specimens for respiratory syncytial virus diagnosis by cell culture, indirect immunofluorescence assay, and enzyme-linked immunosorbent assay.
    J Clin Microbiol. 1987 May;25(5):763-7 PMID: 3294883
  91. Purification of serotype 2 fimbriae of Bordetella pertussis and their identification as a mouse protective antigen.
    Dev Biol Stand. 1985;61:173-85 PMID: 2872103
  92. Bordetella extracytoplasmic adenylate cyclase: actions as a bacterial toxin.
    Dev Biol Stand. 1985;61:21-6 PMID: 2872107
  93. Immunomodulation by Bordetella pertussis: antiviral effects.
    Dev Biol Stand. 1985;61:233-40 PMID: 2872109
  94. Bordetella pertussis filamentous hemagglutinin gene: molecular cloning of a potential coding sequence.
    Dev Biol Stand. 1985;61:265-71 PMID: 2872112
  95. Bordetella adenylate cyclase: host toxicity and diagnostic utility.
    Dev Biol Stand. 1985;61:3-10 PMID: 2872118
  96. Bordetella heat-labile toxin: further purification, characterization and mode of action.
    Dev Biol Stand. 1985;61:93-102 PMID: 3011569
  97. Filamentous hemagglutinin has a major role in mediating adherence of Bordetella pertussis to human WiDr cells.
    Infect Immun. 1986 Jun;52(3):695-701 PMID: 2872165
  98. Comparison of blood-free medium (cyclodextrin solid medium) with Bordet-Gengou medium for clinical isolation of Bordetella pertussis.
    J Clin Microbiol. 1986 Jun;23(6):1046-8 PMID: 2872229
  99. Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication.
    Proc Natl Acad Sci U S A. 1986 Jul;83(13):4631-5 PMID: 2873570
  100. Comparison of three media for culture of Bordetella pertussis.
    Eur J Clin Microbiol. 1986 Jun;5(3):361-3 PMID: 2874987
  101. Helical structure of Bordetella pertussis fimbriae.
    J Bacteriol. 1986 Sep;167(3):968-74 PMID: 2875062
  102. Rapid diagnosis of severe Haemophilus influenzae serotype b infections by monoclonal antibody enzyme immunoassay for outer membrane proteins.
    J Clin Microbiol. 1986 Sep;24(3):440-5 PMID: 3531231
  103. Virulence factors of Bordetella pertussis.
    Annu Rev Microbiol. 1986;40:661-86 PMID: 2877614
  104. Bordetella pertussis adenylate cyclase. Purification, characterization, and radioimmunoassay.
    J Biol Chem. 1986 Dec 5;261(34):16264-9 PMID: 2877986
  105. Bordetella pertussis adenylate cyclase: isolation and purification by calmodulin-sepharose 4B chromatography.
    Infect Immun. 1987 Jan;55(1):129-34 PMID: 2878883
  106. Bordetella pertussis adenylate cyclase: effects of affinity-purified adenylate cyclase on human polymorphonuclear leukocyte functions.
    Infect Immun. 1987 Jan;55(1):135-40 PMID: 2878884
  107. Cloning of the filamentous hemagglutinin of Bordetella pertussis and its expression in Escherichia coli.
    Infect Immun. 1987 Jan;55(1):154-61 PMID: 2878885
  108. Virulence factors of Bordetella bronchiseptica associated with the production of infectious atrophic rhinitis and pneumonia in experimentally infected neonatal swine.
    Infect Immun. 1987 Jan;55(1):217-22 PMID: 3793231
  109. Comparative evaluation of three commercial products and counterimmunoelectrophoresis for the detection of antigens in cerebrospinal fluid.
    J Clin Microbiol. 1984 Aug;20(2):231-4 PMID: 6436296
  110. Detection of Neisseria meningitidis group A, Haemophilus influenzae type b, and Streptococcus pneumoniae antigens in cerebrospinal fluid specimens by antigen capture enzyme-linked immunosorbent assays.
    J Clin Microbiol. 1984 Aug;20(2):259-65 PMID: 6436299
  111. Modified enzyme immunoassay for detecting Neisseria gonorrhoeae antigens.
    J Clin Microbiol. 1984 Oct;20(4):641-3 PMID: 6436313
  112. The concept of pertussis as a toxin-mediated disease.
    Pediatr Infect Dis. 1984 Sep-Oct;3(5):467-86 PMID: 6093069
  113. Diagnosis of whooping cough--a comparison of culture, immunofluorescence and serology with ELISA.
    Scand J Infect Dis. 1984;16(3):281-4 PMID: 6149614
  114. Bordetella pertussis infection in mice: correlation of specific antibodies against two antigens, pertussis toxin, and filamentous hemagglutinin with mouse protectivity in an intracerebral or aerosol challenge system.
    Infect Immun. 1984 Nov;46(2):415-21 PMID: 6542069
  115. Monoclonal antibody against pertussis toxin: effect on toxin activity and pertussis infections.
    Infect Immun. 1984 Nov;46(2):422-8 PMID: 6094351
  116. Protective activities of the filamentous hemagglutinin and the lymphocytosis-promoting factor of Bordetella pertussis in mice.
    J Infect Dis. 1984 Dec;150(6):823-33 PMID: 6094673
  117. Importance of culture in laboratory diagnosis of Bordetella pertussis infections.
    J Clin Microbiol. 1984 Nov;20(5):891-3 PMID: 6096397
  118. Escherichia coli alpha-hemolysin: characteristics and probable role in pathogenicity.
    Microbiol Rev. 1984 Dec;48(4):326-43 PMID: 6394977
  119. Neutralizing antibodies to pertussis toxin in whooping cough.
    J Infect Dis. 1985 Apr;151(4):646-9 PMID: 2857752
  120. Purification and characterization of fimbriae isolated from Bordetella pertussis.
    Infect Immun. 1985 May;48(2):422-7 PMID: 2859248
  121. Bordetella pertussis invasive adenylate cyclase. Partial resolution and properties of its cellular penetration.
    J Biol Chem. 1985 May 10;260(9):5526-32 PMID: 2859287
  122. Characterization of two adhesins of Bordetella pertussis for human ciliated respiratory-epithelial cells.
    J Infect Dis. 1985 Jul;152(1):118-25 PMID: 2861240
  123. Selective primary health care: strategies for control of disease in the developing world. XVII. Pertussis and diphtheria.
    Rev Infect Dis. 1985 May-Jun;7(3):426-33 PMID: 3895357
  124. Comparison of ortho respiratory syncytial virus enzyme-linked immunosorbent assay and HEp-2 cell culture.
    J Clin Microbiol. 1985 Dec;22(6):1071-2 PMID: 4066920
  125. Calmodulin inhibits entry of Bordetella pertussis adenylate cyclase into animal cells.
    Biochemistry. 1985 Nov 5;24(23):6323-8 PMID: 2867777
  126. Purification and characterization of a calmodulin-sensitive adenylate cyclase from Bordetella pertussis.
    Biochemistry. 1985 Nov 5;24(23):6356-62 PMID: 2867778
  127. Survival of Bordetella pertussis in transport media.
    J Clin Pathol. 1986 Jan;39(1):119-20 PMID: 2869056
  128. Applied molecular genetics: new tools for microbiologists and clinicians.
    J Infect Dis. 1986 Mar;153(3):416-30 PMID: 3005422
  129. Detection of respiratory syncytial virus in nasopharyngeal secretions by a biotin-avidin ELISA more sensitive than the fluorescent antibody technique.
    J Med Virol. 1986 Feb;18(2):113-7 PMID: 3512768
  130. Secreted adenylate cyclase of Bordetella pertussis: calmodulin requirements and partial purification of two forms.
    J Bacteriol. 1986 Apr;166(1):290-6 PMID: 2870055
  131. Serological study of Bordetella pertussis and related species.
    J Bacteriol. 1957 Aug;74(2):133-6 PMID: 13475208
  132. Diagnosis of pertussis by the fluorescent-antibody method.
    N Engl J Med. 1960 Oct 27;263:850-1 PMID: 13784792
  133. CULTURE AND FLUORESCENT-ANTIBODY METHODS IN DIAGNOSIS OF WHOOPING COUGH.
    J Bacteriol. 1963 Sep;86:449-51 PMID: 14066420
  134. Beef-heart charcoal agar for the preparation of pertussis vaccines.
    Am J Public Health Nations Health. 1953 Nov;43(11):1466-72 PMID: 13104709
  135. Pertussis; current status of prevention and treatment.
    Pediatr Clin North Am. 1957 Feb;:271-83 PMID: 13400572
  136. Role of antibody to leukocytosis-promoting factor hemagglutinin and to filamentous hemagglutinin in immunity to pertussis.
    Infect Immun. 1981 Mar;31(3):1223-31 PMID: 6262248
  137. Pertussis immunisation and serious acute neurological illness in children.
    Br Med J (Clin Res Ed). 1981 May 16;282(6276):1595-9 PMID: 6786580
  138. Isolation of Bordetella pertussis from swabs.
    Br Med J (Clin Res Ed). 1981 Aug 8;283(6288):403-4 PMID: 6266577
  139. Polymyxin B inactivation of lipopolysaccharide in vaccines of Gram-negative bacteria.
    Infect Immun. 1981 Jul;33(1):315-8 PMID: 6266967
  140. Nature and rates of adverse reactions associated with DTP and DT immunizations in infants and children.
    Pediatrics. 1981 Nov;68(5):650-60 PMID: 7031583
  141. A reappraisal of serotype factors 4, 5 and 6 of Bordetella pertussis.
    J Hyg (Lond). 1982 Feb;88(1):39-46 PMID: 6276465
  142. Enzyme immunoassays for the detection of infectious antigens in body fluids: current limitations and future prospects.
    Rev Infect Dis. 1982 Jan-Feb;4(1):35-68 PMID: 6803327
  143. Detection, isolation, and analysis of a released Bordetella pertussis product toxic to cultured tracheal cells.
    Infect Immun. 1982 May;36(2):782-94 PMID: 6177637
  144. ADP ribosylation of the specific membrane protein of C6 cells by islet-activating protein associated with modification of adenylate cyclase activity.
    J Biol Chem. 1982 Jun 25;257(12):7210-6 PMID: 7200979
  145. Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells.
    Proc Natl Acad Sci U S A. 1982 May;79(10):3162-6 PMID: 6285339
  146. Serological diagnosis of pertussis: IgM, IgA and IgG antibodies against Bordetella pertussis measured by enzyme-linked immunosorbent assay (ELISA).
    Scand J Infect Dis. 1982;14(2):117-22 PMID: 6285449
  147. Phagocyte impotence caused by an invasive bacterial adenylate cyclase.
    Science. 1982 Sep 3;217(4563):948-50 PMID: 6287574
  148. Enzyme-linked immunosorbent assay for detection of respiratory syncytial virus infection: application to clinical samples.
    J Clin Microbiol. 1982 Aug;16(2):329-33 PMID: 6749895
  149. Antigenic relationship between serotype-specific agglutinogen and fimbriae of Bordetella pertussis.
    Infect Immun. 1982 Sep;37(3):1278-81 PMID: 6127315
  150. Ornithine-containing lipid of Bordetella pertussis that carries hemagglutinating activity.
    J Bacteriol. 1982 Nov;152(2):907-10 PMID: 6290456
  151. Serologic diagnosis of whooping cough by an enzyme-linked immunosorbent assay using fimbrial hemagglutinin as antigen.
    J Infect Dis. 1982 Dec;146(6):741-5 PMID: 6128367
  152. Study of a blood-free medium for transport and growth of Bordetella pertussis.
    Health Lab Sci. 1969 Jan;6(1):40-5 PMID: 4305543
  153. Antimicrobial treatment of pertussis.
    J Pediatr. 1969 Nov;75(5):768-81 PMID: 4310467
  154. Bordetella pertussis serotypes in the United States.
    Appl Microbiol. 1969 Oct;18(4):618-21 PMID: 4312923
Article Info
Journal
Clinical microbiology reviews
Abbr.
Clin Microbiol Rev
ISSN
0893-8512
DOI
10.1128/CMR.1.4.365
Published
1988-10-00
Pages
365-76
Language
English
Region
United States
NLM ID
8807282
PMCID
PMC358060
Subset
IM
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