Detection of respiratory syncytial virus in nasal secretions from infants by enzyme-linked immunosorbent assay.

The Journal of infectious diseases ·Vol. 139 ·No. 4 ·1979-04-00 ·Pages 483-6

Chao RK, Fishaut M, Schwartzman JD, McIntosh K

Abstract

An enzyme-linked immunosorbent assay (ELISA) was developed for detection of respiratory syncytial virus (RSV) in nasal secretions from infants with respiratory disease. RSV was detected in 23 of 29 secretions positive for RSV by tissue culture and in one of 36 samples negative for RSV by tissue culture. The ELISA was a simple rapid, and surprisingly sensitive test for identification of RSV infection in infants.

MeSH Terms

Child, Preschool Enzyme-Linked Immunosorbent Assay Humans Immunoenzyme Techniques Nasal Mucosa/metabolism,microbiology Nasopharynx/microbiology Respiratory Syncytial Viruses/isolation & purification Respiratory Tract Infections/microbiology

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Chao R K

Fishaut M

Schwartzman J D

McIntosh K

Article Info

Journal

The Journal of infectious diseases

Abbr.

J Infect Dis

ISSN

0022-1899

DOI

10.1093/infdis/139.4.483

Published

1979-04-00

Pages

483-6

Language

English

Region

United States

NLM ID

0413675

Subset

External Links

PubMed source DOI: 10.1093/infdis/139.4.483 View journal details

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Detection of respiratory syncytial virus in nasal secretions from infants by enzyme-linked immunosorbent assay.

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