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PMID: 23293281 Published · ppublish English Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Establishing and maintaining gene expression patterns: insights from sensory receptor patterning.

Development (Cambridge, England) ·Vol. 140 ·No. 3 ·2013-02-01 ·Pages 493-503

Rister J, Desplan C, Vasiliauskas D

Abstract

In visual and olfactory sensory systems with high discriminatory power, each sensory neuron typically expresses one, or very few, sensory receptor genes, excluding all others. Recent studies have provided insights into the mechanisms that generate and maintain sensory receptor expression patterns. Here, we review how this is achieved in the fly retina and compare it with the mechanisms controlling sensory receptor expression patterns in the mouse retina and in the mouse and fly olfactory systems.

MeSH Terms
Animals Cell Differentiation Compound Eye, Arthropod/cytology,metabolism Drosophila/cytology,genetics,metabolism Drosophila Proteins/genetics,metabolism Gene Expression Regulation Mice Olfactory Mucosa/cytology,metabolism Photoreceptor Cells, Vertebrate/cytology,metabolism Retina/cytology,metabolism Rhodopsin/genetics,metabolism Rod Opsins/genetics,metabolism Sensory Receptor Cells/cytology,metabolism Transcription, Genetic
Chemicals
Drosophila Proteins Rh5 protein, Drosophila Rh6 protein, Drosophila Rod Opsins middle-wavelength opsin short-wavelength opsin Rhodopsin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Rister Jens
Department of Biology, New York University, 1009 Silver Center, 100 Washington Square East, New York, NY 10003-6688, USA.
Desplan Claude
Vasiliauskas Daniel
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Article Info
Journal
Development (Cambridge, England)
Abbr.
Development
ISSN
1477-9129
DOI
10.1242/dev.079095
Published
2013-02-01
Pages
493-503
Language
English
Region
England
NLM ID
8701744
PMCID
PMC3561783
Subset
IM
Grants
NEI NIH HHS · R01 EY013010 · United States
External Links
PubMed source DOI: 10.1242/dev.079095 PMC Full Text View journal details
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