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PMID: 10080101 Published · ppublish English Journal Article Review

Dendritic cells: a link between innate and adaptive immunity.

Journal of clinical immunology ·Vol. 19 ·No. 1 ·1999-01-00 ·Pages 12-25

Palucka K, Banchereau J

Abstract

Dendritic cells (DC) constitute a unique system of cells able to induce primary immune responses. As a component of the innate immune system, DC organize and transfer information from the outside world to the cells of the adaptive immune system. DC can induce such contrasting states as active immune responsiveness or immunological tolerance. Recent years have brought a wealth of information regarding DC biology and pathophysiology, that shows the complexity of this cell system. Although our understanding of DC biology is still in its infancy, we are now in a position to use DC-based immunotherapy protocols to treat cancer and infectious diseases.

MeSH Terms
Dendritic Cells/immunology Humans Immunity Immunity, Cellular Immunity, Innate Immunotherapy Neoplasms/immunology
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Palucka K
Baylor Institute for Immunology Research, Dallas, Texas 75246, USA. ak.palucka@baylordallas.edu
Banchereau J
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Article Info
Journal
Journal of clinical immunology
Abbr.
J Clin Immunol
ISSN
0271-9142
DOI
10.1023/a:1020558317162
Email
ak.palucka@baylordallas.edu
Published
1999-01-00
Pages
12-25
Language
English
Region
Netherlands
NLM ID
8102137
Subset
IM
External Links
PubMed source DOI: 10.1023/a:1020558317162 View journal details
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