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This gene encodes a member of the UNC13 family. UNC13 proteins bind to phorbol esters and diacylglycerol and play important roles in neurotransmitter release at synapses. Single nucleotide polymorphisms in this gene may be associated with sporadic amyotrophic lateral sclerosis. [provided by RefSeq, Feb 2012]
[中文简述(自动翻译):]  该基因编码的UNC13家族的一个成员。 UNC13蛋白质结合佛波醇酯和甘油二酯,并在突触起到神经递质释放重要作用。在该基因的单核苷酸多态性可与散发性肌萎缩性侧索硬化相关联。 [由RefSeq的,2012年2月提供]
UNC13A基因(以及对应的蛋白质)的细胞分布位置:
UNC13A基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Amyotrophic Lateral Sclerosis | 0.366091273 | 8 | 4 | BeFree_CTD_human_GAD_GWASCAT_ORPHANET |
| Fetal Growth Retardation | 0.08 | 1 | 0 | RGD |
| Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
| Amyotrophic Lateral Sclerosis, Sporadic | 0.000542884 | 2 | 1 | BeFree |
| Hyperglycemia | 0.000271442 | 1 | 0 | BeFree |
| Pick Disease of the Brain | 0.000271442 | 1 | 0 | BeFree |
| Frontotemporal dementia | 0.000271442 | 1 | 0 | BeFree |
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