TFAP4(transcription factor AP-4 (activating enhancer binding protein 4)) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

16p13
基因染色体位置图

基因简述

基因简述

Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG (Mermod et al., 1988 [PubMed 2833704]; Hu et al., 1990 [PubMed 2123466]).[supplied by OMIM, Jul 2009]

[中文简述(自动翻译):]  的碱性螺旋 - 环 - 螺旋拉链的转录因子（bHLH结构-ZIP）家族包含碱性结构域，其用于DNA结合，并HLH和邮政编码结构域，其被用于低聚。转录因子的AP4通过结合到对称DNA序列CAGCTG同时激活病毒和细胞基因（Mermod等，1988 [搜索PubMed 2833704];胡等人，1990 [搜索PubMed 2123466]）。[由OMIM，2009年07月供给]

OMIM数据库中对TFAP4基因的介绍     Wikipedia数据库中对TFAP4基因的介绍

基因序列

基因序列

TFAP4基因的碱基序列：[NCBI]

基因突变

基因突变

TFAP4基因的碱基突变：           显示全部snp
rs251730       rs251731       rs251732       rs251733       rs251734       rs251735       rs251736       rs251737       rs251738       rs251739       rs251740       rs251741       rs251742       rs417083       rs1042846       rs2283479       rs2892165       rs3747568       rs3747569       rs3747570       rs3747571       rs4786479       rs6500594       rs7188845       rs8062461       rs12149650       rs12929925       rs13336627       rs28651981       rs34126956       rs34634533       rs60033004       rs60341751       rs60856578       rs71394667       rs73503276       rs73503284      
rs74003265       rs74003266       rs74003268       rs74769988       rs75560023       rs75756769       rs75819425       rs75857521       rs77974162       rs78187005       rs78379133       rs79093503       rs79637522       rs79642041       rs80228979       rs111446931       rs111752627       rs111797121       rs111832163       rs111970184       rs112023218       rs112371680       rs112489448       rs112599352       rs112642422       rs113072510       rs113376057       rs113507774       rs113574452       rs113588475       rs113715150       rs113767502       rs113930962       rs114054842       rs114412351       rs115157743       rs115481035       rs115769827       rs115956785       rs116078567       rs116199055       rs116566927       rs117099821       rs117388563       rs117593304       rs117919747       rs118038069       rs118128454       rs118160344       rs137861287       rs138089742       rs138751824       rs138785355       rs138789825       rs139081750       rs139095393       rs139475760       rs139657794       rs139717481       rs139812014       rs140032266       rs140227708       rs140510691       rs140630343       rs141050705       rs141342100       rs141561659       rs141629754       rs141739069       rs141739930       rs141745578       rs141882803       rs141962785       rs142070465       rs142294337       rs142430286       rs142736216       rs142911293       rs143299976       rs143614815       rs143657362       rs143897238       rs144250856       rs144258089       rs144403225       rs144472187       rs144772233       rs144838759       rs144892069       rs145238604       rs145410892       rs145661547       rs146022068       rs146039637       rs146204016       rs146373710       rs146398440       rs146539090       rs146580278       rs146813689       rs147098490       rs147382209       rs147586338       rs147850361       rs147954237       rs147961036       rs148025174       rs148258464       rs148289477       rs148371505       rs148511881       rs148757233       rs148999505       rs149083106       rs149126170       rs149171981       rs149455776       rs149476922       rs149766060       rs149821372       rs150207807       rs150365616       rs150535299       rs150692798       rs151005950       rs151040592       rs151081715       rs151136336       rs180885316       rs180887421       rs181264449       rs181528751       rs181651937       rs182011837       rs182103723       rs182517257       rs182540737       rs182661357       rs182808005       rs182952209       rs183399068       rs183648464       rs183824611       rs183897713       rs184151435       rs184220716       rs184479849       rs184610114       rs184773932       rs185078624       rs185079772       rs185093079       rs185741245       rs185912358       rs186136507       rs186566591       rs186724921       rs186932348       rs187237570       rs187470980       rs187781357       rs187955480       rs187986103       rs188597334       rs188842265       rs188911659       rs189068470       rs189553908       rs189626133       rs189715789       rs189794954       rs190353810       rs190395634       rs190468679       rs190621625       rs190799178       rs190833233       rs191211312       rs191640914       rs191887899       rs192107859       rs192221929       rs192485438       rs192607530       rs192684018       rs192740619       rs193056230       rs193068648       rs193161360       rs199753022       rs199878048       rs200095427       rs200099469       rs200418884       rs200851221       rs201066218       rs201188737       rs201281864       rs201333358       rs201830089       rs201856455       rs201892227       rs202094455       rs202101705       rs202167502       rs367575118       rs367668965       rs367798809       rs367811874       rs368414950       rs368569984       rs369022161       rs369092753       rs369388241       rs369628159       rs369733498       rs369846368       rs369862660       rs370089018       rs370334406       rs370702615       rs370818941       rs370969208       rs371334031       rs371516876       rs371802223       rs372159354       rs372222253       rs372549314       rs372870160       rs372961075       rs372979225       rs373103497       rs373305869       rs373483713       rs374046464       rs374312620       rs374331139       rs374864714       rs375521966       rs375524177       rs375999150       rs376265216       rs376612667       rs376993133       rs377249379       rs377389684       rs398028606       rs527372739       rs527573373       rs527655348       rs527777657       rs527790173       rs528385650       rs528653842       rs528773919       rs528783655       rs528844717       rs528973428       rs529178145       rs529475513       rs529556746       rs529938327       rs529990666       rs530008391       rs530080750       rs530201431       rs530213779       rs531118760       rs531175045       rs531244278       rs531306727       rs531306871       rs531313905       rs531624851       rs531675134       rs532144202       rs532286187       rs532376200       rs532431587       rs532651114       rs532663885       rs532676896       rs532886561       rs532908964       rs532930467       rs533322966       rs533901768       rs534017380       rs534029353       rs534069798       rs534081935       rs534262366       rs534753677       rs534869240       rs535072907       rs535363526       rs535479869       rs535542035       rs535556469       rs535622889       rs535921565       rs536355516       rs536413029       rs536418569       rs536555461       rs536591060       rs536611417       rs536672887       rs536735719       rs536802884       rs536993249       rs537217515       rs537806277       rs537936127       rs537940802       rs537952283       rs538020223       rs538191485       rs538450530       rs538800486       rs539013474       rs539131896       rs539194784       rs539194894       rs539256286       rs539333671       rs539385691       rs539531427       rs539761651       rs539775490       rs540622640       rs540771763       rs540807216       rs540974138       rs540995103       rs541037398       rs541108461       rs541549703       rs541673281       rs542151032       rs542166452       rs542394892       rs542501582       rs542871556       rs542934940       rs543012776       rs543164705       rs543349039       rs543424880       rs543835144       rs543965052       rs544240152       rs544301980       rs544313912       rs544519628       rs544538850       rs544753781       rs545103866       rs545163566       rs545548634       rs545635193       rs545733888       rs545869688       rs545892317       rs545997819       rs546175957       rs546294800       rs546318536       rs546357943       rs546502306       rs546565571       rs546702332       rs546931678       rs547284707       rs547518968       rs547748085       rs547781376       rs547940657       rs548001716       rs548242470       rs548384892       rs548496758       rs548708571       rs548776952       rs548899971       rs548921333       rs548958846       rs549036294       rs549189548       rs549327094       rs549839860       rs549862257       rs549946859       rs550042422       rs550086616       rs550146199       rs550151819       rs550158418       rs550207759       rs550325687       rs550466196       rs550848550       rs550941069       rs551291002       rs551347203       rs551350546       rs551410256       rs551412526       rs551490101       rs552299525       rs552484308       rs552540805       rs552583910       rs552617268       rs552878285       rs553078687       rs553098239       rs553141986       rs553204717       rs553316713       rs553743312       rs553891109       rs554005630       rs554017911       rs554144831       rs554250807       rs554415495       rs554532061       rs554593456       rs555049420       rs555195778       rs555254237       rs555325656       rs555345764       rs555480699       rs555647151       rs555804200       rs556229680       rs556333576       rs556544459       rs556709318       rs556787606       rs556799616       rs556804686       rs556986267       rs557010897       rs557553294       rs557661861       rs557734991       rs557792189       rs557977706       rs557984064       rs557994944       rs558109234       rs558262049       rs558333014       rs558491546       rs559105284       rs559188143       rs559198287       rs559546974       rs559748226       rs559764758       rs559814469       rs559854345       rs559863783       rs559927554       rs559957546       rs560301552       rs560363597       rs560583428       rs560767698       rs560938647       rs560984332       rs561196970       rs561246369       rs561257928       rs561781259       rs561905408       rs561924419       rs561925676       rs561931330       rs562208427       rs562411120       rs562447581       rs562536997       rs562930008       rs562942084       rs563097867       rs563113048       rs563139075       rs563182559       rs563210826       rs563598953       rs563711110       rs563735601       rs563925193       rs564316584       rs564317602       rs564319619       rs564406401       rs564921487       rs565196593       rs565633347       rs566128284       rs566253690       rs566293955       rs566309502       rs566395460       rs566495205       rs566661865       rs566755516       rs567299747       rs567316908       rs567382726       rs567471160       rs567493276       rs567594456       rs567630500       rs567772537       rs567831994       rs567966872       rs568735558       rs568822881       rs568879166       rs568957562       rs569024928       rs569098568       rs569188470       rs569233820       rs569288375       rs569731915       rs569991539       rs570011464       rs570104253       rs570171966       rs570314985       rs570378040       rs570384020       rs570756971       rs571140565       rs571266897       rs571309689       rs571369852       rs571426712       rs571504190       rs571917695       rs572167541       rs572438629       rs572539828       rs572567690       rs572930550       rs573051221       rs573108007       rs573326763       rs573388877       rs573601049       rs573673960       rs573857491       rs574183460       rs574229264       rs574264942       rs574429851       rs574487705       rs574977027       rs575405143       rs575512981       rs575522801       rs575535457       rs575602691       rs575622232       rs575665996       rs575709450       rs576082638       rs576214921       rs576465357       rs576631108       rs576724161       rs576738732       rs576796776       rs577138760       rs577653078       rs577738969       rs577916263       rs577998741       rs578013658       rs578192164       rs745348395       rs745401284       rs745457943       rs745735035       rs745740125       rs745900801       rs745954768       rs746158860       rs746519936       rs746602719       rs746748274       rs746774211       rs746843232       rs746998172       rs747023902       rs747329832       rs747381090       rs747460288       rs747665066       rs747814941       rs747877984       rs748246936       rs748313561       rs748485805       rs748515594       rs748728800       rs748809683       rs748864822       rs749089137       rs749571092       rs749631309       rs749815187       rs750162521       rs750166633       rs750181453       rs750188115       rs750236535       rs750531933       rs750987680       rs750996470       rs751032830       rs751034744       rs751265715       rs751669729       rs752101904       rs752166298       rs752214011       rs752470093       rs752700927       rs752779088       rs753032523       rs753107491       rs753204825       rs753592219       rs753603709       rs753605523       rs753811953       rs753953127       rs754265133       rs754568388       rs754834764       rs754886119       rs754907282       rs755332264       rs755385285       rs755423707       rs755494562       rs755686241       rs755851865       rs755945532       rs756200251       rs756549532       rs756777721       rs756818988       rs756925183       rs757028215       rs757039827       rs757081124       rs757664748       rs757964861       rs757965906       rs758178082       rs758343881       rs758359127       rs758604748       rs758616359       rs758653095       rs758708073       rs758746576       rs758801652       rs758964440       rs759084483       rs759376749       rs759681899       rs759818510       rs759904959       rs760018553       rs760098052       rs760511509       rs760938485       rs761166475       rs761334173       rs761671551       rs762237536       rs762355234       rs762601421       rs762742957       rs763047053       rs763260975       rs763624896       rs763648095       rs763806202       rs763985363       rs763985479       rs764017835       rs764607746       rs764701684       rs764881973       rs764951287       rs765000273       rs765117577       rs765360439       rs765492125       rs765504365       rs765700476       rs765979176       rs766163277       rs766506107       rs766513305       rs766594042       rs766777684       rs766852828       rs766941634       rs767084889       rs767414668       rs767566309       rs767712582       rs767861866       rs767887069       rs767887745       rs768098928       rs768247184       rs768302218       rs768561016       rs768649035       rs768737372       rs768898988       rs769201510       rs769256327       rs769291692       rs769400412       rs769500943       rs769674930       rs769862653       rs769956250       rs770007766       rs770013166       rs770127011       rs770388696       rs770597535       rs770608536       rs770947593       rs771000874       rs771091138       rs771156880       rs771263678       rs771720881       rs771744713       rs772047423       rs772135551       rs772195844       rs772257306       rs772606514       rs772766739       rs773064984       rs773188146       rs773294958       rs773419768       rs773475420       rs773917935       rs774042045       rs774252415       rs774349696       rs774481442       rs774602369       rs774710021       rs774929316       rs774964786       rs775042936       rs775104271       rs775107214       rs775943575       rs776103967       rs776180199       rs776225185       rs776312696       rs776497020       rs776706110       rs776949222       rs777081003       rs777093673       rs777095847       rs777148532       rs777328586       rs777452608       rs777490443       rs777971498       rs778336870       rs778516548       rs778649498       rs778676872       rs778711009       rs778977359       rs778994569       rs779007146       rs779049926       rs779182329       rs779419002       rs779440676       rs779650897       rs779850295       rs779923987       rs780088020       rs780131911       rs780160064       rs780215391       rs780339724       rs780341787       rs780573227       rs780865305       rs780964489       rs780975353       rs781131167       rs781214935       rs781763631      

基因表达

基因表达

TFAP4基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GTATTTCATGGTGCCCACTC
59
AATGTTGGCAAGGCTACAG
59
AAGTGATAGGAGGGCTCTG
58
GACATTGATGTGGTGGGAG
58
TAGGAGGGCTCTGTAGGTG
59
GACATTGATGTGGTGGGAG
58
GTATTTCATGGTGCCCACTC
59
GAATGTTGGCAAGGCTACAG
60
TATTTCATGGTGCCCACTC
58
GTTTCCTCCGTCTACAGAG
57
GATTCCAGTCCCTCAAGACC
60
AGATGTACTCGGCTGTCTG
59
GATTCCAGTCCCTCAAGACC
60
AGATGTACTCGGCTGTCTG
59
GAAGTGATAGGAGGGCTCTG
59
ACATTGATGTGGTGGGAGG
60
TAGAATTCGCCACTCTCCC
59
GTGGAAGATGAGACCTGGAG
60
TATTTCATGGTGCCCACTC
58
AATGTTGGCAAGGCTACAG
59

转录因子

转录因子

转录因子
影响类型
PubMed链接
CDKN1A
Activation
19270520
CLCN5
Unknown
15086899
IFNG
Unknown
12836278
MDM2
Repression
19505873
MUC4
Unknown
11418607
PPP2R2B
Repression
20533062
SALL2
Activation
21228219

基因本体信息

TFAP4基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

TFAP4基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0046983
I3L254(UniProtKB)
IEA
GO:0000978
Q01664(UniProtKB)
IEA
GO:0001077
Q01664(UniProtKB)
IEA
GO:0003677
Q01664(UniProtKB)
IDA
GO:0003705
Q01664(UniProtKB)
IDA
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005515
Q01664(UniProtKB)
IPI
GO:0005634
Q01664(UniProtKB)
IDA
GO:0005634
Q01664(UniProtKB)
IDA
GO:0005634
Q01664(UniProtKB)
IDA
GO:0005634
Q01664(UniProtKB)
IDA
GO:0005634
Q01664(UniProtKB)
IDA
GO:0006366
Q01664(UniProtKB)
IEA
GO:0006461
Q01664(UniProtKB)
IDA
GO:0006978
Q01664(UniProtKB)
IDA
GO:0008285
Q01664(UniProtKB)
IMP
GO:0017053
Q01664(UniProtKB)
ISS
GO:0042803
Q01664(UniProtKB)
IPI
GO:0042826
Q01664(UniProtKB)
IPI
GO:0042826
Q01664(UniProtKB)
IPI
GO:0043065
Q01664(UniProtKB)
IDA
GO:0043392
Q01664(UniProtKB)
IDA
GO:0043392
Q01664(UniProtKB)
IDA
GO:0043565
Q01664(UniProtKB)
IDA
GO:0043922
Q01664(UniProtKB)
IDA
GO:0043922
Q01664(UniProtKB)
IDA
GO:0043922
Q01664(UniProtKB)
NAS
GO:0043923
Q01664(UniProtKB)
IDA
GO:0044212
Q01664(UniProtKB)
IDA
GO:0044212
Q01664(UniProtKB)
IDA
GO:0045736
Q01664(UniProtKB)
IDA
GO:0045892
Q01664(UniProtKB)
IDA
GO:0045892
Q01664(UniProtKB)
IMP
GO:0045892
Q01664(UniProtKB)
IDA
GO:0045892
Q01664(UniProtKB)
IDA
GO:0045893
Q01664(UniProtKB)
IMP
GO:0045944
Q01664(UniProtKB)
IEA
GO:0070888
Q01664(UniProtKB)
IDA
GO:0070888
Q01664(UniProtKB)
IDA
GO:0070888
Q01664(UniProtKB)
IDA
GO:0070888
Q01664(UniProtKB)
IDA
GO:0070888
Q01664(UniProtKB)
IDA
GO:0071157
Q01664(UniProtKB)
IMP
GO:0071549
Q01664(UniProtKB)
IEA
GO:2001269
Q01664(UniProtKB)
IEA
GO:0003713
Q01664(UniProtKB)
IDA
GO:0046982
Q01664(UniProtKB)
IMP

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控TFAP4基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Colorectal Carcinoma 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree
Liver carcinoma 0.000271442 1 0 BeFree

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