SPINT1(serine peptidase inhibitor, Kunitz type 1) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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15q13.3
基因染色体位置图

The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质是Kunitz结构家族的一个成员丝氨酸蛋白酶抑制剂。该蛋白质是特异于HGF活化剂的强效抑制剂,并且被认为参与了在损伤组织的蛋白水解活化的HGF的调节。选择性剪接结果编码不同亚型多个变种。 [由RefSeq的,2008年7月提供]

SPINT1基因的碱基序列:[NCBI]
SPINT1基因的碱基突变:           显示全部snp
rs637995       rs668750       rs680493       rs689733       rs689736       rs690572       rs2291618       rs3759797       rs3759798       rs11549914       rs11549915       rs12323939       rs28422875       rs35749050       rs60255874       rs60442578       rs61281824       rs71104742       rs71471877       rs74011889       rs75508484       rs77542134       rs77751046       rs79650787       rs111377916       rs111695130       rs112045778       rs114339215       rs116764060       rs117909540       rs138089109       rs140263254       rs140494089       rs141793805       rs142099552       rs142550825       rs142567105      
rs144502231       rs144779474       rs145578767       rs145999931       rs146144462       rs147855160       rs148314547       rs148571737       rs148755059       rs150545640       rs181323121       rs181713612       rs182610558       rs183049896       rs183869583       rs184351510       rs185584758       rs185992983       rs186940962       rs187144614       rs188599243       rs189283987       rs190902803       rs191636410       rs193249326       rs199768768       rs199965511       rs200006775       rs200164851       rs200486135       rs201697101       rs201791058       rs202049185       rs367826054       rs368309266       rs368898985       rs371381706       rs372286432       rs372434962       rs372603645       rs373367867       rs373492914       rs375042808       rs376333579       rs376462674       rs527843362       rs528305869       rs528531585       rs529594760       rs530493598       rs531027811       rs533934728       rs534338613       rs535058654       rs536678624       rs536804732       rs538192184       rs539216353       rs539256440       rs539650061       rs540314447       rs540376245       rs543267493       rs544670776       rs544733342       rs545435856       rs545760845       rs547592131       rs548835562       rs549949023       rs550318144       rs550490920       rs550834279       rs551303454       rs551948021       rs553670634       rs554013687       rs554663536       rs555336330       rs556458078       rs556993873       rs557336289       rs559113102       rs560119858       rs561391828       rs561840994       rs563904331       rs564030385       rs564330111       rs565057703       rs565266707       rs565330442       rs565651652       rs567046472       rs567266762       rs567298915       rs569816678       rs569934873       rs570647857       rs571207488       rs571792262       rs573514866       rs574193664       rs574535418       rs575566748       rs575927737       rs577159528       rs577438130       rs577678367       rs577786546       rs745480373       rs745605901       rs745897404       rs746570646       rs746642409       rs747449334       rs747470663       rs747611192       rs748516131       rs749103967       rs749501212       rs749617310       rs750002104       rs750538694       rs750594103       rs750828679       rs751536917       rs751601912       rs751615505       rs752549240       rs753648167       rs753701598       rs754360257       rs754696591       rs754937693       rs754984432       rs755497485       rs755644673       rs755857978       rs756511656       rs756638082       rs757578578       rs757639019       rs758002274       rs758400991       rs758550828       rs758912610       rs759670416       rs759786834       rs760177902       rs760563007       rs760568200       rs760684271       rs762138463       rs762409531       rs763112135       rs763340218       rs763951886       rs764076608       rs764578411       rs764606165       rs765098289       rs765609743       rs765625282       rs765974709       rs767343780       rs767493476       rs768272269       rs768721508       rs768884488       rs769149631       rs769812130       rs770138846       rs770584218       rs772651501       rs772747991       rs772897453       rs772902109       rs773871617       rs773925092       rs775539622       rs775688195       rs775797665       rs776710634       rs776753954       rs777009212       rs777048289       rs777628182       rs779081337       rs779633506       rs779964722       rs780664488       rs780877965       rs781566038       rs781620292       rs17649       rs582639       rs583031       rs643875       rs647423       rs647930       rs658752       rs659232       rs661745       rs662236       rs675262       rs676180       rs689589       rs689626       rs690136       rs690165       rs690365       rs690458       rs690467       rs690660       rs1049585       rs1049587       rs1049588       rs1049592       rs1049595       rs1049596       rs1049598       rs2307098       rs2412569       rs2412570       rs3189773       rs3207638       rs3736287       rs4924508       rs7165897       rs7173709       rs8028552       rs8030341       rs17658212       rs28369017       rs28454328       rs35970287       rs58107694       rs59896818       rs60125661       rs60248715       rs60619762       rs72735651       rs73400524       rs74011890       rs74011891       rs74011892       rs74011893       rs74603924       rs74758527       rs74819355       rs74970396       rs76579941       rs76849037       rs77221247       rs77724323       rs78643367       rs79652488       rs79799549       rs111363328       rs111673689       rs111821673       rs111903266       rs112296929       rs113258061       rs113483685       rs113593518       rs113723725       rs113979041       rs114306054       rs114680996       rs114942580       rs114985996       rs115016208       rs115480243       rs115942136       rs116374191       rs116786220       rs116845898       rs117454282       rs117519517       rs118004939       rs138167951       rs138242530       rs138258462       rs138264463       rs138341632       rs138578385       rs138832805       rs138999714       rs139238995       rs139263716       rs139286505       rs139331998       rs139505388       rs139553809       rs140303340       rs140432663       rs141062061       rs141146817       rs141448135       rs141573491       rs141921370       rs142240169       rs142668532       rs142750993       rs142948345       rs142969118       rs143067716       rs143426105       rs143677034       rs143800693       rs143834587       rs143937737       rs144011977       rs144093488       rs144228229       rs144740183       rs144827721       rs144910384       rs144993960       rs145193299       rs145330357       rs145514521       rs145902250       rs146565021       rs146724340       rs146780117       rs146821605       rs147244113       rs147350003       rs147386305       rs147747345       rs147838664       rs148102042       rs148173333       rs148433906       rs148573816       rs148937494       rs149068458       rs149094427       rs149291015       rs149463227       rs149619158       rs149720019       rs149968293       rs150337144       rs150664806       rs151013944       rs151160609       rs180995891       rs181278957       rs181343456       rs181730519       rs182093669       rs182189906       rs183092730       rs183255808       rs183330451       rs183730962       rs183829210       rs183971781       rs184233395       rs184588241       rs184747051       rs185113106       rs185126434       rs185192817       rs185295979       rs185537748       rs186624122       rs186666268       rs186856875       rs188421778       rs188473238       rs188842738       rs189203000       rs189232833       rs189251813       rs189502341       rs189569975       rs190080368       rs190115671       rs190827400       rs191058611       rs191108233       rs191317085       rs191529857       rs191716065       rs191817849       rs192496097       rs192693266       rs193104263       rs199651027       rs199742351       rs199960318       rs200165352       rs200169204       rs200268560       rs200316060       rs200346403       rs200347151       rs200727334       rs200801441       rs200901498       rs200944233       rs201206539       rs201305915       rs201341729       rs201440714       rs201483554       rs201712230       rs201870536       rs202026481       rs202037909       rs202094724       rs202101923       rs202226710       rs202231232       rs202235325       rs367761216       rs367887953       rs367901148       rs368299730       rs368407939       rs368522046       rs368525506       rs368701058       rs368703966       rs368856152       rs368950895       rs369006639       rs369178359       rs369410887       rs369498136       rs369534728       rs369798368       rs369960455       rs370052891       rs370165480       rs370356137       rs370529238       rs370640557       rs370860535       rs371165907       rs371185922       rs371354846       rs371597596       rs371706199       rs372216484       rs372353456       rs372434804       rs372720759       rs372900261       rs372963829       rs373214738       rs373361566       rs373488579       rs373852046       rs373907498       rs373996078       rs374398975       rs374709054       rs374753795       rs374831095       rs374993828       rs375070927       rs375162891       rs375374965       rs375441760       rs375785043       rs376143378       rs376446817       rs376769889       rs376996258       rs377189543       rs377394193       rs377395500       rs377397915       rs377422901       rs377450581       rs527431405       rs527444243       rs527593241       rs527905104       rs527978841       rs528104647       rs528374744       rs528531578       rs528594888       rs528770079       rs529046188       rs529080359       rs529147761       rs529270954       rs529403453       rs529803091       rs530268228       rs530558804       rs530618058       rs531819678       rs531960369       rs532105078       rs532167357       rs533038791       rs533672227       rs533945820       rs534001027       rs534015209       rs534071249       rs534699680       rs534910689       rs535094442       rs535555037       rs536219742       rs536449107       rs536520007       rs536739942       rs536932389       rs536990848       rs537802242       rs537934098       rs538124649       rs538300679       rs538946996       rs539193032       rs539531771       rs539714356       rs539867813       rs540242097       rs540578921       rs541233616       rs541391229       rs541574135       rs542018844       rs542424206       rs542521692       rs542530903       rs542656853       rs543109124       rs543669960       rs543847698       rs544153329       rs544174288       rs544226895       rs544276854       rs544348204       rs544409522       rs544556664       rs544893712       rs544954620       rs545079301       rs545141233       rs545143969       rs545207208       rs545366375       rs545465349       rs545626682       rs546841557       rs547127279       rs547210035       rs547284408       rs547544390       rs547640281       rs547653608       rs547715857       rs547972507       rs548395522       rs548437798       rs548507647       rs548573277       rs548899286       rs549018143       rs549471887       rs549527089       rs549560898       rs549701857       rs549710809       rs549970820       rs550011460       rs550670846       rs550721403       rs550731694       rs550759166       rs551185408       rs551423451       rs552486820       rs552498669       rs552560045       rs552741060       rs552950106       rs553755283       rs553814273       rs553818570       rs554862260       rs555002494       rs555727815       rs555854410       rs556124346       rs556221443       rs556643875       rs556716868       rs556928763       rs556943826       rs557005190       rs557587369       rs557596293       rs558065292       rs558319307       rs558716605       rs558841618       rs559116733       rs559553236       rs559612135       rs560182945       rs560241973       rs560570846       rs560835462       rs560850491       rs560850517       rs561068162       rs561939782       rs562087979       rs562790200       rs563184898       rs563188703       rs563651785       rs563713298       rs564184501       rs564342962       rs564648382       rs564712434       rs565210195       rs565331876       rs566195564       rs566587122       rs566910438       rs567092463       rs567165796       rs567841365       rs567902360       rs568092090       rs568093980       rs568158679       rs568229739       rs568272391       rs568370909       rs568432379       rs569128354       rs569343243       rs569543610       rs570142233       rs570561364       rs570604355       rs570806857       rs570924061       rs571268875       rs571367074       rs572052797       rs572269767       rs572676908       rs572926145       rs573081257       rs573726222       rs574054546       rs574596866       rs574788382       rs575193511       rs575316377       rs575428414       rs575604277       rs575645344       rs575739063       rs576199545       rs576737092       rs577079725       rs577372439       rs578102832       rs745308738       rs745318370       rs746008701       rs746272116       rs746299778       rs746313007       rs746327235       rs746559628       rs746682514       rs746728134       rs746971808       rs746991747       rs746995222       rs747016519       rs747228024       rs747311049       rs747319563       rs747321527       rs747444395       rs747537677       rs747835032       rs747956197       rs748090236       rs748183999       rs748696756       rs748910361       rs749026884       rs749322836       rs749602451       rs749661933       rs749891465       rs750171118       rs750282603       rs750341676       rs750456267       rs750564988       rs751324782       rs751377881       rs751441702       rs751704058       rs751749451       rs751802448       rs752038956       rs752042615       rs752203791       rs752258840       rs752497967       rs752770933       rs753069864       rs753293935       rs753395243       rs753499776       rs753574618       rs753688491       rs753743567       rs754036462       rs754089289       rs754526601       rs754820636       rs754949576       rs755087916       rs755237849       rs755295823       rs755325964       rs755576190       rs755628866       rs755772967       rs756006556       rs756093279       rs756303462       rs756303633       rs756418054       rs756719173       rs756821220       rs756874290       rs757022193       rs757144564       rs757233557       rs757395236       rs757397930       rs757540941       rs757608091       rs758081110       rs758081313       rs758134493       rs758358779       rs758550476       rs758647699       rs758648974       rs758738308       rs758838184       rs758859311       rs759131239       rs759250856       rs759288567       rs759426202       rs759454528       rs759751294       rs760060715       rs760112686       rs760163087       rs760398562       rs760620930       rs760934150       rs760983795       rs760988634       rs761140852       rs761598510       rs761668755       rs761698281       rs761836216       rs761960637       rs762259999       rs762266128       rs762321060       rs762387274       rs762797799       rs763163082       rs763268606       rs763466698       rs763467419       rs763597848       rs764066951       rs764290756       rs764309903       rs764449165       rs764549083       rs764692557       rs764959864       rs765154925       rs765260877       rs765380286       rs765386177       rs765670168       rs765708154       rs766065211       rs766196867       rs766409945       rs766418662       rs766616647       rs766934158       rs766968486       rs767021695       rs767088838       rs767407822       rs767440427       rs767544380       rs767732170       rs767910208       rs767957785       rs768069377       rs768181887       rs768239228       rs768359783       rs768600133       rs768662239       rs768715360       rs768716685       rs769224433       rs769356804       rs769581820       rs769979852       rs770028255       rs770327461       rs770362786       rs770376036       rs770379397       rs770430430       rs770452732       rs770500676       rs770579190       rs770768040       rs770968528       rs771095345       rs771146617       rs771179581       rs771417650       rs771515991       rs771587233       rs771690847       rs771699340       rs771968874       rs772076000       rs772107124       rs772299783       rs772588036       rs772725757       rs772741357       rs772850260       rs772946138       rs773286770       rs773349518       rs773727033       rs773756301       rs773856522       rs773904695       rs774024222       rs774073564       rs774323770       rs774331856       rs774388624       rs774428982       rs774735884       rs774791082       rs774993708       rs775099101       rs775321975       rs775375005       rs775390954       rs775428221       rs775606275       rs775650053       rs775838328       rs775989180       rs776066378       rs776247587       rs776383282       rs776885776       rs776986895       rs777138347       rs777215407       rs777322435       rs777340322       rs777481374       rs777505359       rs777568295       rs777647076       rs778010063       rs778030782       rs778073739       rs778341187       rs778623056       rs778702999       rs778757571       rs778988352       rs779145941       rs779158560       rs779282995       rs779520487       rs779730861       rs779767066       rs779781919       rs780125788       rs780131293       rs780307229       rs780369905       rs780421858       rs780547953       rs780859371       rs780990788       rs781044211       rs781761957       rs781774831      

SPINT1基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GAGAGGAAAGACCCAAACC
58
GGCAGTAGTCTTCTGTCTG
57
CTATGGTGGTTGTTACGGC
59
CATCCTTCTTGGAGATGCC
58
GCATAGACTTGAAGGTACAACC
59
TGGTTTGGGTCTTTCCTCTC
60
CCTATGGTGGTTGTTACGG
58
CATCCTTCTTGGAGATGCC
58
CTATGGTGGTTGTTACGGC
59
CATCCTTCTTGGAGATGCC
58
GAGGAAAGACCCAAACCAG
58
AGGCAGTAGTCTTCTGTCTG
59
TGAGACTCTGACCTTTCCTC
59
TTGCAGAGTCCTGTGTCTG
60
CCTATGGTGGTTGTTACGG
58
CATCCTTCTTGGAGATGCC
58
AGTGACTAGCTCAGACCAC
59
AGGCAGTAGTCTTCTGTCTG
59
GCATAGACTTGAAGGTACAACC
59
TGGTTTGGGTCTTTCCTCTC
60
      尚未收录相关数据

SPINT1基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

SPINT1基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0004867
H3BMB6(UniProtKB)
IEA
GO:0010951
H3BMB6(UniProtKB)
IEA
GO:0016021
H3BMB6(UniProtKB)
IEA
GO:0004867
H3BNW5(UniProtKB)
IEA
GO:0010951
H3BNW5(UniProtKB)
IEA
GO:0016021
H3BNW5(UniProtKB)
IEA
GO:0004867
H3BR01(UniProtKB)
IEA
GO:0010951
H3BR01(UniProtKB)
IEA
GO:0016021
H3BR01(UniProtKB)
IEA
GO:0004867
H3BSM2(UniProtKB)
IEA
GO:0010951
H3BSM2(UniProtKB)
IEA
GO:0004867
H3BTQ8(UniProtKB)
IEA
GO:0010951
H3BTQ8(UniProtKB)
IEA
GO:0004867
H3BVD9(UniProtKB)
IEA
GO:0010951
H3BVD9(UniProtKB)
IEA
GO:0016021
H3BVD9(UniProtKB)
IEA
GO:0001843
O43278(UniProtKB)
IEA
GO:0004867
O43278(UniProtKB)
IEA
GO:0005576
O43278(UniProtKB)
TAS
GO:0005615
O43278(UniProtKB)
IDA
GO:0005886
O43278(UniProtKB)
IEA
GO:0005886
O43278(UniProtKB)
IEA
GO:0010951
O43278(UniProtKB)
IEA
GO:0016020
O43278(UniProtKB)
TAS
GO:0030198
O43278(UniProtKB)
IEA
GO:0045687
O43278(UniProtKB)
IEA
GO:0060670
O43278(UniProtKB)
IEA
GO:0060674
O43278(UniProtKB)
IEA
GO:0070062
O43278(UniProtKB)
IDA
GO:0070062
O43278(UniProtKB)
IDA
GO:0071773
O43278(UniProtKB)
IEA
GO:2000178
O43278(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控SPINT1基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Liver Cirrhosis 0.080542884 3 0 BeFree_RGD
Malignant neoplasm of breast 0.003452799 4 0 BeFree_GAD
Colorectal Neoplasms 0.00272435 1 0 LHGDN
Gastrointestinal Neoplasms 0.00272435 1 0 LHGDN
Chronic Obstructive Airway Disease 0.00272435 1 0 LHGDN
Prostatic Neoplasms 0.00272435 1 0 LHGDN
Neoplasm Metastasis 0.001357209 5 0 BeFree
Breast Carcinoma 0.001085767 4 0 BeFree
Colorectal Carcinoma 0.000814326 3 0 BeFree
Influenza 0.000814326 3 0 BeFree
Pancreatic carcinoma 0.000814326 3 0 BeFree
Glioblastoma 0.000542884 2 0 BeFree
Hepatitis, Chronic 0.000542884 2 0 BeFree
Liver diseases 0.000542884 2 0 BeFree
Liver neoplasms 0.000542884 2 0 BeFree
Malignant neoplasm of stomach 0.000542884 2 0 BeFree
Tumor Progression 0.000542884 2 0 BeFree
Fibrosis, Liver 0.000542884 2 0 BeFree
MRSA - Methicillin resistant Staphylococcus aureus infection 0.000542884 2 0 BeFree
Malignant neoplasm of pancreas 0.000542884 2 0 BeFree
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Stomach Carcinoma 0.000542884 2 0 BeFree
Mammary Neoplasms 0.000542884 2 0 BeFree
Cirrhosis 0.000542884 2 0 BeFree
Adenocarcinoma 0.000271442 1 0 BeFree
Adenoma 0.000271442 1 0 BeFree
Anaplasia 0.000271442 1 0 BeFree
Biliary Atresia 0.000271442 1 0 BeFree
Malignant neoplasm of urinary bladder 0.000271442 1 0 BeFree
Malignant tumor of colon 0.000271442 1 0 BeFree
Malignant neoplasm of endometrium 0.000271442 1 0 BeFree
Non-Small Cell Lung Carcinoma 0.000271442 1 0 BeFree
Renal Cell Carcinoma 0.000271442 1 0 BeFree
Squamous cell carcinoma 0.000271442 1 0 BeFree
Fibroid Tumor 0.000271442 1 0 BeFree
Medulloblastoma 0.000271442 1 0 BeFree
Neonatal hepatitis 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Uterine Fibroids 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lung 0.000271442 1 0 BeFree
Leiomyosarcoma of uterus 0.000271442 1 0 BeFree
Endometrial Carcinoma 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Hyperhomocysteinemia 0.000271442 1 0 BeFree
Colon Carcinoma 0.000271442 1 0 BeFree
Carcinoma of bladder 0.000271442 1 0 BeFree
Colorectal cancer metastatic 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree
Adenocarcinoma of large intestine 0.000271442 1 0 BeFree
Xenograft Model 0.000271442 1 0 BeFree
LATERAL MENINGOCELE SYNDROME 0.000271442 1 0 BeFree
Uterine Corpus Cancer 0.000271442 1 0 BeFree
Homocysteinemia 0.000271442 1 0 BeFree
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