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This gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
[中文简述(自动翻译):]  该基因编码一个家族,其作为蛋白酶抑制剂蛋白质的成员。 IgA肾病被上调该基因的表达,并已发现的突变引起掌跖角化病,长岛类型。选择性剪接结果在多个抄本变形。 [由RefSeq的,2014年6月提供]
SERPINB7基因(以及对应的蛋白质)的细胞分布位置:
SERPINB7基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| PALMOPLANTAR KERATODERMA, NAGASHIMA TYPE | 0.24 | 0 | 4 | CLINVAR_ORPHANET |
| Nephritis | 0.08 | 1 | 0 | RGD |
| IGA Glomerulonephritis | 0.02408977 | 8 | 0 | BeFree_GAD_LHGDN |
| Kidney Failure, Chronic | 0.002638474 | 1 | 0 | BeFree_GAD |
| Malignant neoplasm of ovary | 0.002367032 | 1 | 0 | GAD |
| Palmoplantar Keratosis | 0.000542884 | 2 | 0 | BeFree |
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