RING1(ring finger protein 1) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

6p21.3
基因染色体位置图

基因简述

基因简述

This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基因属于无名指家庭成员，其中编码蛋白质的特点是RING结构域，涉及到锌指结构域锌结合基序。基因产物可结合的DNA，并可以作为一个转录阻遏作用。它与多聚聚硫组蛋白复合物有关。该基因产物的多梳家族蛋白BMI1，EDR1和CBX4互动，并与大型核领域这些蛋白质共定位。它通过其富含甘氨酸的C端结构域的CBX4蛋白相互作用。该基因映射到HLA类II区，它是邻接的环指基因FABGL和HKE4。 [由RefSeq的，2008年7月提供]

OMIM数据库中对RING1基因的介绍     Wikipedia数据库中对RING1基因的介绍

基因序列

基因序列

RING1基因的碱基序列：[NCBI]

基因突变

基因突变

RING1基因的碱基突变：           显示全部snp
rs421446       rs114938492       rs115715785       rs188772152       rs199611405       rs199961622       rs200247614       rs201546042       rs201694173       rs367760363       rs369503455       rs529082155       rs533351648       rs539418164       rs544693683       rs544856926       rs550245851       rs556120952       rs560211121       rs563002362       rs566473292       rs567886650       rs749654732       rs752714032       rs754817043       rs756343610       rs758688676       rs759417817       rs760218875       rs763027794       rs766031711       rs768946922       rs770794469       rs776357578       rs778113209       rs781095234       rs107822      
rs9469381       rs111665837       rs113024181       rs141339230       rs150807262       rs181496797       rs368453799       rs373182574       rs377295270       rs529048313       rs532850145       rs533803638       rs540115652       rs545145326       rs545304982       rs551474630       rs554270411       rs556439180       rs561681995       rs566320787       rs577999130       rs745352198       rs747501721       rs748489235       rs750530565       rs751451723       rs753126162       rs753882211       rs754008063       rs755240213       rs758722929       rs762665311       rs762799751       rs764009328       rs764073673       rs766438833       rs769543022       rs769631421       rs770417766       rs772511681       rs775281007       rs775477458       rs778338953       rs779092219       rs779288721       rs780149818       rs213208       rs213209       rs1047194       rs2854027       rs2854028       rs6902761       rs7775179       rs9296089       rs9469382       rs9469383       rs41266705       rs61736933       rs73741545       rs73741546       rs74564669       rs75993808       rs112289675       rs112834551       rs113307811       rs113695132       rs114759012       rs114887773       rs115201624       rs115651908       rs116064471       rs116123477       rs117630006       rs117787041       rs138374633       rs138399139       rs138993284       rs140654280       rs140711452       rs140772954       rs141446845       rs144154291       rs144714948       rs144721528       rs145088291       rs145706732       rs145844429       rs146537860       rs147196393       rs147412967       rs149252597       rs149445528       rs150736071       rs182268724       rs182594008       rs183234183       rs185329479       rs186721571       rs187013758       rs188519057       rs188833596       rs189823518       rs190132746       rs190201273       rs191327078       rs192922121       rs199540463       rs199674713       rs200721333       rs200859722       rs201208970       rs201600661       rs201798356       rs368593830       rs368886108       rs369175859       rs369187454       rs369799440       rs370250823       rs370422048       rs370456986       rs370939105       rs371179024       rs371453957       rs371574266       rs371857967       rs372588934       rs373037542       rs373469632       rs373580122       rs373876015       rs373967616       rs374501579       rs375029256       rs375351974       rs375610066       rs376291922       rs376511612       rs376894525       rs376930787       rs377366654       rs377384493       rs377682205       rs527272198       rs527340598       rs528493311       rs528555677       rs528777843       rs529108271       rs530227248       rs531038847       rs531198951       rs532138667       rs534418562       rs536553738       rs536885673       rs537492111       rs538896365       rs539256609       rs541306676       rs542096213       rs543164083       rs544111297       rs544984915       rs547927195       rs548265712       rs548325369       rs549113572       rs550472864       rs551171332       rs552624034       rs553966146       rs553974955       rs554135886       rs559658765       rs560092287       rs560230952       rs561648204       rs562510944       rs562834031       rs563877808       rs564464013       rs564866501       rs565297168       rs565360264       rs565944825       rs568474263       rs569812532       rs570772279       rs571728065       rs572254268       rs572255547       rs574747939       rs575783621       rs576041574       rs576044848       rs576815289       rs577818493       rs745442074       rs745482741       rs745713825       rs745765950       rs746185117       rs746404253       rs746583497       rs746786544       rs746889405       rs746909439       rs747392344       rs747437599       rs747672241       rs747880357       rs747881990       rs748115540       rs748308232       rs748416763       rs748574413       rs748658587       rs748722806       rs748926440       rs749024397       rs749443720       rs749448892       rs749601573       rs749761032       rs749900494       rs749950359       rs750187590       rs750192143       rs750313133       rs750358408       rs750425187       rs750633764       rs750781868       rs751197447       rs751311317       rs751357270       rs751565403       rs751841099       rs751929105       rs752021849       rs752088517       rs752161594       rs752298137       rs752555950       rs752665608       rs752955571       rs753342089       rs753403352       rs753419465       rs753806303       rs754040833       rs754139415       rs754288952       rs754377307       rs754640364       rs755324202       rs755377213       rs755623237       rs755800374       rs756080863       rs756812489       rs756863836       rs757121144       rs757178244       rs757433349       rs757834893       rs758068405       rs758229954       rs758554493       rs758591908       rs758713322       rs758793149       rs758918302       rs758957921       rs759467758       rs759522793       rs759607187       rs759625577       rs759828026       rs759991167       rs760436035       rs760794938       rs761056004       rs761112473       rs761130056       rs761398688       rs761661869       rs761844469       rs761847933       rs762078557       rs762198334       rs762381214       rs762975986       rs763112152       rs763222116       rs763276911       rs763568949       rs763884906       rs764202157       rs764481447       rs764803565       rs765152735       rs765206912       rs765241745       rs765252259       rs765319932       rs765426482       rs765666813       rs765725767       rs765840860       rs766418741       rs766484158       rs766682335       rs766851770       rs767181284       rs767409956       rs767418739       rs767599927       rs767949273       rs768158987       rs768258382       rs768444512       rs768600490       rs768709960       rs768948218       rs769159319       rs769261393       rs769288897       rs769737800       rs770027759       rs770128593       rs770204859       rs770236826       rs770825613       rs770862747       rs771143710       rs771410653       rs771692596       rs771796514       rs771949928       rs772002768       rs772292330       rs772374587       rs772430673       rs772781309       rs772908337       rs773155792       rs773166594       rs773288562       rs773463887       rs773565706       rs773589384       rs773751992       rs774028517       rs774183521       rs774249639       rs774263456       rs774678671       rs774708052       rs774865448       rs774939947       rs774990832       rs774992909       rs775373890       rs775562388       rs775607509       rs775690676       rs775819775       rs775970204       rs776010042       rs776580590       rs776652843       rs776748603       rs777183990       rs777347964       rs777365685       rs778030870       rs778061902       rs778074553       rs778190373       rs778424305       rs778639609       rs778703784       rs779160866       rs779320607       rs779473339       rs779498989       rs779572032       rs779651653       rs779772040       rs779809205       rs779870029       rs780016095       rs780074052       rs780187512       rs780585109       rs780878041       rs780990761       rs781039413       rs781115948       rs781245294       rs781325018       rs781762045      

基因表达

基因表达

RING1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AGAAATTGAGCTCGTGTTCC
59
GTTGTCTTCACATACCTCGT
58
AGAAATTGAGCTCGTGTTCC
59
GTTGTCTTCACATACCTCGTC
59
TGGAGAAATTGAGCTCGTG
58
GTCTTCACATACCTCGTCTG
58
AGAAATTGAGCTCGTGTTCC
59
GTTGTCTTCACATACCTCGTC
59
TGGAGAAATTGAGCTCGTG
58
GTCTTCACATACCTCGTCTG
58
AGAAATTGAGCTCGTGTTCC
59
GTTGTCTTCACATACCTCGT
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

RING1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RING1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001739
Q06587(UniProtKB)
IEA
GO:0003682
Q06587(UniProtKB)
IEA
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005515
Q06587(UniProtKB)
IPI
GO:0005634
Q06587(UniProtKB)
IDA
GO:0005634
Q06587(UniProtKB)
IDA
GO:0005654
Q06587(UniProtKB)
IDA
GO:0005654
Q06587(UniProtKB)
TAS
GO:0005654
Q06587(UniProtKB)
TAS
GO:0005654
Q06587(UniProtKB)
TAS
GO:0005654
Q06587(UniProtKB)
TAS
GO:0005737
Q06587(UniProtKB)
IDA
GO:0006351
Q06587(UniProtKB)
IEA
GO:0008270
Q06587(UniProtKB)
IEA
GO:0009952
Q06587(UniProtKB)
IEA
GO:0016607
Q06587(UniProtKB)
IEA
GO:0016874
Q06587(UniProtKB)
IEA
GO:0016925
Q06587(UniProtKB)
TAS
GO:0016925
Q06587(UniProtKB)
TAS
GO:0031519
Q06587(UniProtKB)
IDA
GO:0031519
Q06587(UniProtKB)
IDA
GO:0035102
Q06587(UniProtKB)
IDA
GO:0035102
Q06587(UniProtKB)
IDA
GO:0035518
Q06587(UniProtKB)
IDA
GO:0045892
Q06587(UniProtKB)
IDA
GO:0048593
Q06587(UniProtKB)
IEA
GO:0050790
Q06587(UniProtKB)
IEA
GO:0097027
Q06587(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控RING1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Prostatic Neoplasms 0.00272435 1 0 LHGDN
Renal Cell Carcinoma 0.002367032 1 0 GAD
Diabetes Mellitus, Insulin-Dependent 0.002367032 1 0 GAD
Head and Neck Neoplasms 0.002367032 1 0 GAD
Kidney Neoplasm 0.002367032 1 0 GAD
Lupus Erythematosus, Systemic 0.002367032 1 0 GAD
Neoplasm Recurrence, Local 0.002367032 1 0 GAD
Neoplasms, Second Primary 0.002367032 1 0 GAD
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Hypertrophic Cardiomyopathy 0.000271442 1 0 BeFree
Lymphoma, Follicular 0.000271442 1 3 BeFree
Lymphoma, Non-Hodgkin 0.000271442 1 3 BeFree
Lymphoma, Large-Cell, Follicular 0.000271442 1 3 BeFree
Idiopathic pulmonary hypertension 0.000271442 1 0 BeFree
Pancreatic carcinoma 0.000271442 1 0 BeFree
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 0.000271442 1 0 BeFree
Malignant neoplasm of pancreas 0.000271442 1 0 BeFree
Pancreatic Ductal Adenocarcinoma 0.000271442 1 0 BeFree
Pulmonary arterial hypertension 0.000271442 1 0 BeFree
Pulmonary Hypertension, Primary, 1, With Hereditary Hemorrhagic Telangiectasia 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

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