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The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
[中文简述(自动翻译):]  由该基因编码的蛋白质是GAP1家族GTP酶激活蛋白质的成员。该基因产物刺激正常RAS p21的但不是它的致癌对应的GTP酶活性。作为RAS功能的抑制剂,蛋白质增强导致的RAS的非活性的GDP结合形式,从而允许细胞增殖和分化的控制RAS蛋白的弱内在GTP酶活性。选择性剪接结果在多个抄本变形。 [由RefSeq的,2014年12月提供]
RASA2基因(以及对应的蛋白质)的细胞分布位置:
RASA2基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| melanoma | 0.12 | 2 | 0 | CTD_human |
| Noonan Syndrome | 0.12 | 0 | 0 | ORPHANET |
| Malignant neoplasm of prostate | 0.000542884 | 2 | 0 | BeFree |
| Prostate carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Colorectal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Creutzfeldt-Jakob disease | 0.000271442 | 1 | 1 | BeFree |
| Leukemia, Myelocytic, Acute | 0.000271442 | 1 | 0 | BeFree |
| Neoplasm Metastasis | 0.000271442 | 1 | 0 | BeFree |
| Skin Diseases, Bullous | 0.000271442 | 1 | 0 | BeFree |
| Colon Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Colorectal Cancer | 0.000271442 | 1 | 0 | BeFree |
| Prostate cancer, familial | 0.000271442 | 1 | 0 | BeFree |
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