OXT(oxytocin/neurophysin I prepropeptide) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

20p13
基因染色体位置图

基因简述

基因简述

This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013]

[中文简述(自动翻译):]  这个基因编码被处理以产生催产素和neurophysin一催产素是被合成为在其载体蛋白neurophysin I.与neurophysin一起沿丘脑无效前体的垂体后叶激素的前体蛋白，它是打包成神经分泌囊泡和轴突运送到神经垂体神经末梢，在那里它被存储的或分泌到血液中。该前体似乎同时被沿轴突向垂体后输送到被激活。这种激素分娩和哺乳期间收缩平滑肌。它还参与认知，宽容，适应和复杂性和产妇的行为，以及在水的排泄和心血管功能的调节。 [由RefSeq的，2013年12月提供]

OMIM数据库中对OXT基因的介绍     Wikipedia数据库中对OXT基因的介绍

基因序列

基因序列

OXT基因的碱基序列：[NCBI]

基因突变

基因突变

OXT基因的碱基突变：           显示全部snp
rs877172       rs913554       rs2016899       rs2740207       rs2740208       rs2740209       rs2740210       rs2770378       rs3761246       rs3761248       rs4813625       rs4813626       rs6037477       rs6051567       rs6051569       rs6115781       rs6133010       rs6139004       rs11908423       rs17339677       rs34097556       rs34386558       rs34582008       rs67662484       rs71195817       rs72318358       rs73088749       rs77555429       rs77929946       rs78737453       rs111504347       rs111869749       rs114029030       rs114164503       rs114807108       rs114898677       rs115115918      
rs116054832       rs138515501       rs139164047       rs139297313       rs140340676       rs140417823       rs141127137       rs141507004       rs143310142       rs144102485       rs144356842       rs145060338       rs146547827       rs146951885       rs147571703       rs148345638       rs149951170       rs150460488       rs151193548       rs180884281       rs182019273       rs182120351       rs183559163       rs184901299       rs187330373       rs187902615       rs188154095       rs188182216       rs189701266       rs190114844       rs191702555       rs192687599       rs193060356       rs200007313       rs200687129       rs367995752       rs368458476       rs371393986       rs371824508       rs372802613       rs373657534       rs375773351       rs376999853       rs397699169       rs398040033       rs528082083       rs528127282       rs528977569       rs528993005       rs530850964       rs531723485       rs532067338       rs532531181       rs532596883       rs533724449       rs534030683       rs534222512       rs536023797       rs536347770       rs537759693       rs539143832       rs539689313       rs539753029       rs540191122       rs540720856       rs541907433       rs542826580       rs543898025       rs544064595       rs544124796       rs545165050       rs546062672       rs546313791       rs547564852       rs549321289       rs549408865       rs549522864       rs550156955       rs550228466       rs550720585       rs550914194       rs551647367       rs553753631       rs555355748       rs555500993       rs555677297       rs555695260       rs556199742       rs556572399       rs556685549       rs557745184       rs557886872       rs559269903       rs559708303       rs560533492       rs561538751       rs561539423       rs562085810       rs562221429       rs562281739       rs563485134       rs563491966       rs563554690       rs564419946       rs565281573       rs565618091       rs566411110       rs567083750       rs567128901       rs567191373       rs568103836       rs569108490       rs571242695       rs571804459       rs572013267       rs572538302       rs572881172       rs572895881       rs572959073       rs573075762       rs573545612       rs575506235       rs577219198       rs745621567       rs745785053       rs746072874       rs746654297       rs746778163       rs747053795       rs747745164       rs747804069       rs748761146       rs748920446       rs749574021       rs750117244       rs750397892       rs750636956       rs750887422       rs751076155       rs751216617       rs751761595       rs751849789       rs752289803       rs752643746       rs752871256       rs752965107       rs753618080       rs753801172       rs754339207       rs754359819       rs754921568       rs755910037       rs755998155       rs756696929       rs757025204       rs757043276       rs757260942       rs757502666       rs757727500       rs757875451       rs758663169       rs758750989       rs759546426       rs760462577       rs760506151       rs760734814       rs760874748       rs761046494       rs761523918       rs761550944       rs761913603       rs762160052       rs762480562       rs763076895       rs763433348       rs763492150       rs763513226       rs763643438       rs764278771       rs764370773       rs764706709       rs765219954       rs765365623       rs765533530       rs766175141       rs766717591       rs766735906       rs767358613       rs767740954       rs767757530       rs768181518       rs768850071       rs769080766       rs769081933       rs769117175       rs770770313       rs770870371       rs770939146       rs771019635       rs771185241       rs771699855       rs771807803       rs772062757       rs772188179       rs772302953       rs772956485       rs773118626       rs773224171       rs773421373       rs774028375       rs774594224       rs774628368       rs774935191       rs775023112       rs775323599       rs775772937       rs775999284       rs776648205       rs776739685       rs776867777       rs777434163       rs777879919       rs778259448       rs778462465       rs778480856       rs779511085       rs780493512       rs781109269       rs781195575       rs781332744       rs781498966       rs781621537       rs6084257       rs6084258       rs6115776       rs6115777       rs6115778       rs6115779       rs6139000       rs6139001       rs9798512       rs11697250       rs75903183       rs77079464       rs79902198       rs80026968       rs117730124       rs138915624       rs140354930       rs142182944       rs144855748       rs149427176       rs150654765       rs180732367       rs183140253       rs186339370       rs188574836       rs190740318       rs191801475       rs377384486       rs528584678       rs529896860       rs530504934       rs530873617       rs537150641       rs538271068       rs540742468       rs541416863       rs541628493       rs541688519       rs552232024       rs552257629       rs552743374       rs554570773       rs557625518       rs558679202       rs559144881       rs564288929       rs569635112       rs569890465       rs570597357       rs575107939       rs575560121      

基因表达

基因表达

OXT基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TGCTACATCCAGAACTGCC
60
GTAGTTCTCCTCCTGGCAG
59
CCTGCTACATCCAGAACTG
58
GTAGTTCTCCTCCTGGCAG
59
CTGCTACATCCAGAACTGC
58
GTAGTTCTCCTCCTGGCAG
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

OXT基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

OXT基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001975
P01178(UniProtKB)
IEA
GO:0002027
P01178(UniProtKB)
IEA
GO:0002125
P01178(UniProtKB)
IEA
GO:0005185
P01178(UniProtKB)
IEA
GO:0005576
P01178(UniProtKB)
TAS
GO:0005576
P01178(UniProtKB)
TAS
GO:0005576
P01178(UniProtKB)
TAS
GO:0005576
P01178(UniProtKB)
TAS
GO:0005615
P01178(UniProtKB)
IEA
GO:0005829
P01178(UniProtKB)
IEA
GO:0007165
P01178(UniProtKB)
TAS
GO:0007204
P01178(UniProtKB)
IEA
GO:0007507
P01178(UniProtKB)
IEA
GO:0007565
P01178(UniProtKB)
IEA
GO:0007613
P01178(UniProtKB)
IEA
GO:0007625
P01178(UniProtKB)
IEA
GO:0009744
P01178(UniProtKB)
IEA
GO:0010701
P01178(UniProtKB)
IEA
GO:0014823
P01178(UniProtKB)
IEA
GO:0030141
P01178(UniProtKB)
IEA
GO:0030431
P01178(UniProtKB)
IEA
GO:0031855
P01178(UniProtKB)
IEA
GO:0032094
P01178(UniProtKB)
IEA
GO:0032308
P01178(UniProtKB)
IEA
GO:0032355
P01178(UniProtKB)
IEA
GO:0032526
P01178(UniProtKB)
IEA
GO:0032570
P01178(UniProtKB)
IEA
GO:0034695
P01178(UniProtKB)
IEA
GO:0035176
P01178(UniProtKB)
IEA
GO:0035811
P01178(UniProtKB)
IEA
GO:0035815
P01178(UniProtKB)
IEA
GO:0042220
P01178(UniProtKB)
IEA
GO:0042538
P01178(UniProtKB)
IEA
GO:0042711
P01178(UniProtKB)
IEA
GO:0042713
P01178(UniProtKB)
IEA
GO:0042755
P01178(UniProtKB)
IEA
GO:0042756
P01178(UniProtKB)
IEA
GO:0043195
P01178(UniProtKB)
IEA
GO:0043434
P01178(UniProtKB)
IEA
GO:0045472
P01178(UniProtKB)
IEA
GO:0045776
P01178(UniProtKB)
IEA
GO:0045777
P01178(UniProtKB)
IEA
GO:0045778
P01178(UniProtKB)
IEA
GO:0045925
P01178(UniProtKB)
IEA
GO:0050806
P01178(UniProtKB)
IEA
GO:0051384
P01178(UniProtKB)
IEA
GO:0051591
P01178(UniProtKB)
IEA
GO:0051602
P01178(UniProtKB)
IEA
GO:0051930
P01178(UniProtKB)
IEA
GO:0051965
P01178(UniProtKB)
IEA
GO:0060179
P01178(UniProtKB)
IEA
GO:0060406
P01178(UniProtKB)
IEA
GO:0060450
P01178(UniProtKB)
IEA
GO:0060455
P01178(UniProtKB)
IEA
GO:0070474
P01178(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控OXT基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Hypertensive disease 0.200542884 5 0 BeFree_CTD_human_RGD
Pain 0.2 3 0 CTD_human_RGD
Autistic Disorder 0.136068609 29 0 BeFree_CTD_human_GAD_LHGDN
Anxiety Disorders 0.121628651 7 0 BeFree_CTD_human
Colonic Neoplasms 0.12 1 0 CTD_human
Comatose 0.12 3 0 CTD_human
Disseminated Intravascular Coagulation 0.12 1 0 CTD_human
Dysmenorrhea 0.12 1 0 CTD_human
Edema 0.12 2 0 CTD_human
Tonic-Clonic Epilepsy 0.12 2 0 CTD_human
Fetal Death 0.12 1 0 CTD_human
Fetal Distress 0.12 1 0 CTD_human
Flushing 0.12 1 0 CTD_human
Headache 0.12 1 0 CTD_human
Hyponatremia 0.12 3 0 CTD_human
Hypotension 0.12 1 0 CTD_human
Inflammation 0.12 1 0 CTD_human
Ischemia 0.12 1 0 CTD_human
Mammary Neoplasms, Experimental 0.12 2 0 CTD_human
Muscle Hypertonia 0.12 1 0 CTD_human
Polyuria 0.12 1 0 CTD_human
Prostatic Diseases 0.12 1 0 CTD_human
Seizures 0.12 6 0 CTD_human
Spasm 0.12 4 0 CTD_human
Taste Disorders 0.12 1 0 CTD_human
Water Intoxication 0.12 8 0 CTD_human
Weight Gain 0.12 1 0 CTD_human
Hyperactive behavior 0.12 1 0 CTD_human
Weight decreased 0.12 1 0 CTD_human
Dehydration 0.080271442 2 0 BeFree_RGD
Myocardial Reperfusion Injury 0.08 1 0 RGD
Reperfusion Injury 0.08 1 0 RGD
Gastric ulcer 0.08 1 0 RGD
COGNITIVE FUNCTION 1, SOCIAL 0.004614512 17 0 BeFree
Atrial Septal Defects 0.003800186 14 0 BeFree
Osteosarcoma 0.002995792 2 0 BeFree_LHGDN
Autism Spectrum Disorders 0.002714419 10 0 BeFree
Irritable Bowel Syndrome 0.002638474 1 1 BeFree_GAD
Breast Carcinoma 0.002442977 9 0 BeFree
Malignant neoplasm of breast 0.002171535 8 0 BeFree
Pituitary Diseases 0.001900093 7 0 BeFree
Schizophrenia 0.001628651 6 0 BeFree
Mental Depression 0.001357209 5 0 BeFree
Depressive disorder 0.001357209 5 0 BeFree
Obesity 0.001085767 4 0 BeFree
Mental disorders 0.000814326 3 0 BeFree
Small cell carcinoma of lung 0.000814326 3 0 BeFree
Malignant neoplasm of prostate 0.000814326 3 0 BeFree
Social fear 0.000814326 3 0 BeFree
Prostate carcinoma 0.000814326 3 0 BeFree
Antisocial Personality Disorder 0.000542884 2 0 BeFree
Choriocarcinoma 0.000542884 2 0 BeFree
Neuroblastoma 0.000542884 2 0 BeFree
Unipolar Depression 0.000542884 2 0 BeFree
Central neuroblastoma 0.000542884 2 0 BeFree
Major Depressive Disorder 0.000542884 2 0 BeFree
Mammary Neoplasms 0.000542884 2 0 BeFree
Anorexia 0.000271442 1 0 BeFree
Anorexia Nervosa 0.000271442 1 0 BeFree
Separation Anxiety Disorder 0.000271442 1 0 BeFree
Borderline Personality Disorder 0.000271442 1 0 BeFree
Squamous cell carcinoma 0.000271442 1 0 BeFree
Developmental Disabilities 0.000271442 1 0 BeFree
Dermatitis, Atopic 0.000271442 1 0 BeFree
Down Syndrome 0.000271442 1 0 BeFree
Eczema 0.000271442 1 0 BeFree
Fragile X Syndrome 0.000271442 1 0 BeFree
Hydatidiform Mole 0.000271442 1 0 BeFree
Obesity, Morbid 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Phobia, Social 0.000271442 1 0 BeFree
Prader-Willi Syndrome 0.000271442 1 0 BeFree
Psychotic Disorders 0.000271442 1 0 BeFree
Dermatologic disorders 0.000271442 1 0 BeFree
Post-Traumatic Stress Disorder 0.000271442 1 0 BeFree
Holoprosencephaly 0.000271442 1 0 BeFree
Nephrogenic Diabetes Insipidus 0.000271442 1 0 BeFree
Williams Syndrome 0.000271442 1 0 BeFree
Neuroendocrine Tumors 0.000271442 1 0 BeFree
Depression, Postpartum 0.000271442 1 1 BeFree
Antisocial behavior 0.000271442 1 0 BeFree
Pick Disease of the Brain 0.000271442 1 0 BeFree
Malignant neoplasm of lung 0.000271442 1 0 BeFree
Frontotemporal dementia 0.000271442 1 0 BeFree
Mixed anxiety and depressive disorder 0.000271442 1 0 BeFree
Mood Disorders 0.000271442 1 0 BeFree
Osteosarcoma of bone 0.000271442 1 0 BeFree
Epithelial ovarian cancer 0.000271442 1 0 BeFree
Carcinoma of lung 0.000271442 1 0 BeFree
Anxiety state 0.000271442 1 0 BeFree
Psychotic symptom 0.000271442 1 0 BeFree
Sarcoma 0.000271442 1 0 BeFree
Anxiety neurosis (finding) 0.000271442 1 0 BeFree
Separation anxiety disorder of childhood 0.000271442 1 0 BeFree
Neurodevelopmental Disorders 0.000271442 1 0 BeFree
androgen independent prostate cancer 0.000271442 1 0 BeFree
Non-Neoplastic Disorder 0.000271442 1 0 BeFree
NEUROTICISM 0.000271442 1 1 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

我要说两句
热门评论
还没有评论，赶快来抢沙发吧。

登陆

用户名:

密    码:

联系方式

山东省济南市 高新区 崇华路359号 三庆世纪财富中心C1115室

电话： 0531-88819269

E-mail: product@genelibs.com

微信公众号

扫一扫右方二维码，关注微信订阅号，实时查看信息，关注医学生物学动态。

版权所有 © 2016.Genelibs 济南弘晖生物技术有限公司 鲁ICP备13024435号-2