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The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2010]
[中文简述(自动翻译):]  这个基因的产物是活化的T细胞的DNA结合转录复合核因子的成员。这种复杂的由至少两部分组成:即易位至对T细胞受体(TCR)的刺激细胞核和诱导型核成分的预先存在的胞质部分。这个家庭的其他成员参与也形成这一复杂。该基因的产物在基因表达的T细胞和不成熟的胸腺细胞的调节作用。编码不同亚型的几个变种成绩单已经确定了这个基因。 [由RefSeq的,2010年11月提供]
NFATC3基因(以及对应的蛋白质)的细胞分布位置:
NFATC3基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Schizophrenia | 0.12 | 1 | 1 | GWASCAT |
| Infection | 0.00272435 | 1 | 0 | LHGDN |
| Malignant neoplasm of breast | 0.000271442 | 1 | 0 | BeFree |
| Diabetes | 0.000271442 | 1 | 0 | BeFree |
| Diabetes Mellitus | 0.000271442 | 1 | 0 | BeFree |
| Pulmonary Hypertension | 0.000271442 | 1 | 0 | BeFree |
| leukemia | 0.000271442 | 1 | 0 | BeFree |
| Prostatic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Virus Diseases | 0.000271442 | 1 | 0 | BeFree |
| Fibrillation | 0.000271442 | 1 | 0 | BeFree |
| Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of gastrointestinal tract | 0.000271442 | 1 | 0 | BeFree |
| Valvular disease | 0.000271442 | 1 | 0 | BeFree |
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