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HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  HLA-E属于HLA I类重链旁系同源基??因。这个I类分子是由一个重链和一个轻链(β-2微球蛋白)的异源二聚体。重链被锚定在膜中。 HLA-E结合从其他我类分子的前导肽衍生肽受限制的子集。重链是大约45 kDa和其基因含有8个外显子。外显子1编码前导肽,外显子2和3编码的α1和α2结构域,其中两个结合肽,外显子4编码素α3域,外显子5编码跨膜区,和外显子6和7编码的胞质尾区。 [由RefSeq的,2008年7月提供]
HLA-E基因(以及对应的蛋白质)的细胞分布位置:
HLA-E基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Parapsoriasis | 0.12 | 1 | 0 | CTD_human |
| Myocardial Ischemia | 0.080271442 | 2 | 0 | BeFree_CTD_mouse |
| Diabetes Mellitus, Insulin-Dependent | 0.02904428 | 107 | 0 | BeFree |
| Autoimmune Diseases | 0.028501397 | 105 | 0 | BeFree |
| HIV Infections | 0.027806623 | 86 | 2 | BeFree_GAD |
| Lupus Erythematosus, Systemic | 0.020825079 | 68 | 0 | BeFree_GAD |
| melanoma | 0.02009663 | 65 | 0 | BeFree_LHGDN |
| Rheumatoid Arthritis | 0.017100838 | 63 | 1 | BeFree |
| Behcet Syndrome | 0.013625632 | 14 | 1 | BeFree_GAD_LHGDN |
| Graft-vs-Host Disease | 0.012072926 | 19 | 0 | BeFree_GAD_LHGDN |
| Multiple Sclerosis | 0.010857675 | 40 | 0 | BeFree |
| Ankylosing spondylitis | 0.010510288 | 30 | 0 | BeFree_GAD |
| Diabetes | 0.009229024 | 34 | 0 | BeFree |
| Diabetes Mellitus | 0.009229024 | 34 | 0 | BeFree |
| Psoriasis | 0.008338753 | 22 | 1 | BeFree_GAD |
| Infection | 0.008173051 | 3 | 0 | LHGDN |
| Celiac Disease | 0.006514605 | 24 | 0 | BeFree |
| Virus Diseases | 0.005700279 | 21 | 0 | BeFree |
| Malignant neoplasm of breast | 0.005428837 | 20 | 0 | BeFree |
| Breast Carcinoma | 0.005428837 | 20 | 0 | BeFree |
| Bare lymphocyte syndrome 2 | 0.005428837 | 20 | 0 | BeFree |
| Bare Lymphocyte Syndrome | 0.005157396 | 19 | 0 | BeFree |
| Anemia, Sickle Cell | 0.005091382 | 1 | 0 | GAD_LHGDN |
| Gestational Diabetes | 0.005005506 | 3 | 0 | BeFree_GAD |
| Cancer of Nasopharynx | 0.004734064 | 2 | 0 | GAD |
| Graves Disease | 0.004614512 | 17 | 0 | BeFree |
| Hepatitis B | 0.00434307 | 16 | 4 | BeFree |
| Arthritis | 0.004071628 | 15 | 0 | BeFree |
| Renal Cell Carcinoma | 0.004071628 | 15 | 0 | BeFree |
| Colorectal Carcinoma | 0.003800186 | 14 | 0 | BeFree |
| Experimental Autoimmune Encephalomyelitis | 0.003800186 | 14 | 0 | BeFree |
| Hereditary hemochromatosis | 0.003800186 | 14 | 2 | BeFree |
| Cardiomyopathy, Hypertrophic, Familial | 0.003800186 | 14 | 0 | BeFree |
| Colon Carcinoma | 0.003528744 | 13 | 0 | BeFree |
| Colorectal Cancer | 0.003528744 | 13 | 0 | BeFree |
| Liver carcinoma | 0.003528744 | 13 | 0 | BeFree |
| Tuberculosis | 0.003257302 | 12 | 0 | BeFree |
| Mucocutaneous Lymph Node Syndrome | 0.003181358 | 3 | 0 | BeFree_GAD |
| leukemia | 0.002985861 | 11 | 0 | BeFree |
| Lymphoma | 0.002985861 | 11 | 0 | BeFree |
| Myasthenia Gravis | 0.002985861 | 11 | 0 | BeFree |
| Schizophrenia | 0.002985861 | 11 | 0 | BeFree |
| Autoimmune thyroid disease | 0.002985861 | 11 | 0 | BeFree |
| Bacterial Infections | 0.002909916 | 3 | 0 | BeFree_GAD |
| Coronary Aneurysm | 0.002909916 | 2 | 0 | BeFree_GAD |
| Neuroblastoma | 0.002714419 | 10 | 0 | BeFree |
| Systemic Scleroderma | 0.002714419 | 10 | 0 | BeFree |
| Cardiomyopathies | 0.002714419 | 10 | 0 | BeFree |
| Nasopharyngeal carcinoma | 0.002714419 | 10 | 0 | BeFree |
| Arthritis, Psoriatic | 0.002442977 | 9 | 0 | BeFree |
| Malignant tumor of colon | 0.002442977 | 9 | 0 | BeFree |
| Hemochromatosis | 0.002442977 | 9 | 2 | BeFree |
| Hepatitis C | 0.002442977 | 9 | 0 | BeFree |
| Malaria | 0.002442977 | 9 | 0 | BeFree |
| Multiple Myeloma | 0.002442977 | 9 | 0 | BeFree |
| Neoplasm Metastasis | 0.002442977 | 9 | 0 | BeFree |
| Sarcoidosis | 0.002442977 | 9 | 1 | BeFree |
| Diabetes, Autoimmune | 0.002442977 | 9 | 0 | BeFree |
| Combined immunodeficiency | 0.002442977 | 9 | 0 | BeFree |
| Central neuroblastoma | 0.002442977 | 9 | 0 | BeFree |
| Juvenile rheumatoid arthritis | 0.002442977 | 9 | 0 | BeFree |
| Spontaneous abortion | 0.002367032 | 1 | 0 | GAD |
| Chorioamnionitis | 0.002367032 | 1 | 0 | GAD |
| Fetal Membranes, Premature Rupture | 0.002367032 | 1 | 0 | GAD |
| Premature Obstetric Labor | 0.002367032 | 1 | 0 | GAD |
| Pre-Eclampsia | 0.002367032 | 1 | 0 | GAD |
| Premature Birth | 0.002367032 | 1 | 0 | GAD |
| Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified | 0.002367032 | 1 | 0 | GAD |
| Primary biliary cirrhosis | 0.002171535 | 8 | 0 | BeFree |
| Ulcerative Colitis | 0.002171535 | 8 | 0 | BeFree |
| Glioma | 0.002171535 | 8 | 0 | BeFree |
| Severe Combined Immunodeficiency | 0.002171535 | 8 | 0 | BeFree |
| Hepatitis, Autoimmune | 0.002171535 | 8 | 0 | BeFree |
| Tumor Immunity | 0.002171535 | 8 | 0 | BeFree |
| Diabetes Mellitus, Non-Insulin-Dependent | 0.001900093 | 7 | 0 | BeFree |
| Immunologic Deficiency Syndromes | 0.001900093 | 7 | 0 | BeFree |
| Lupus Vulgaris | 0.001900093 | 7 | 0 | BeFree |
| Lupus Erythematosus, Discoid | 0.001900093 | 7 | 0 | BeFree |
| Lupus Erythematosus | 0.001900093 | 7 | 0 | BeFree |
| Stomach Carcinoma | 0.001900093 | 7 | 0 | BeFree |
| Hyperlipoproteinemia Type IIa | 0.001900093 | 7 | 0 | BeFree |
| Juvenile arthritis | 0.001900093 | 7 | 0 | BeFree |
| Squamous cell carcinoma | 0.001628651 | 6 | 0 | BeFree |
| Common Variable Immunodeficiency | 0.001628651 | 6 | 0 | BeFree |
| Crohn Disease | 0.001628651 | 6 | 3 | BeFree |
| Influenza | 0.001628651 | 6 | 0 | BeFree |
| Thyroiditis | 0.001628651 | 6 | 0 | BeFree |
| Diffuse Large B-Cell Lymphoma | 0.001628651 | 6 | 0 | BeFree |
| Immunoglobulin A deficiency (disorder) | 0.001628651 | 6 | 0 | BeFree |
| Tumor Progression | 0.001628651 | 6 | 0 | BeFree |
| Cervix carcinoma | 0.001628651 | 6 | 0 | BeFree |
| Carcinogenesis | 0.001628651 | 6 | 0 | BeFree |
| Prostate carcinoma | 0.001628651 | 6 | 0 | BeFree |
| Spondylarthropathies | 0.001628651 | 6 | 0 | BeFree |
| Arthritis, Collagen-Induced | 0.001628651 | 6 | 0 | BeFree |
| Sarcoma | 0.001628651 | 6 | 0 | BeFree |
| Immunoglobulin a deficiency 1 | 0.001628651 | 6 | 0 | BeFree |
| Hypertrophic Cardiomyopathy | 0.001357209 | 5 | 0 | BeFree |
| Malignant tumor of cervix | 0.001357209 | 5 | 0 | BeFree |
| Cytomegalovirus Infections | 0.001357209 | 5 | 0 | BeFree |
| Scleroderma | 0.001357209 | 5 | 0 | BeFree |
| Glioblastoma | 0.001357209 | 5 | 0 | BeFree |
| IGA Glomerulonephritis | 0.001357209 | 5 | 0 | BeFree |
| Inflammatory Bowel Diseases | 0.001357209 | 5 | 0 | BeFree |
| Myeloid Leukemia, Chronic | 0.001357209 | 5 | 0 | BeFree |
| Adult T-Cell Lymphoma/Leukemia | 0.001357209 | 5 | 0 | BeFree |
| Malignant neoplasm of stomach | 0.001357209 | 5 | 0 | BeFree |
| Myositis | 0.001357209 | 5 | 0 | BeFree |
| Chagas Disease | 0.001357209 | 5 | 0 | BeFree |
| Vitiligo | 0.001357209 | 5 | 0 | BeFree |
| Psoriasis vulgaris | 0.001357209 | 5 | 0 | BeFree |
| Malignant neoplasm of prostate | 0.001357209 | 5 | 0 | BeFree |
| Primary immune deficiency disorder | 0.001357209 | 5 | 0 | BeFree |
| Acute GVH disease | 0.001357209 | 5 | 0 | BeFree |
| VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) | 0.001357209 | 5 | 0 | BeFree |
| Arteriosclerosis | 0.001085767 | 4 | 0 | BeFree |
| Asthma | 0.001085767 | 4 | 0 | BeFree |
| Atherosclerosis | 0.001085767 | 4 | 0 | BeFree |
| Malignant neoplasm of urinary bladder | 0.001085767 | 4 | 0 | BeFree |
| Non-Small Cell Lung Carcinoma | 0.001085767 | 4 | 0 | BeFree |
| Congestive heart failure | 0.001085767 | 4 | 0 | BeFree |
| Herpes Simplex Infections | 0.001085767 | 4 | 0 | BeFree |
| Arthropathy | 0.001085767 | 4 | 0 | BeFree |
| Leprosy | 0.001085767 | 4 | 0 | BeFree |
| Chronic Lymphocytic Leukemia | 0.001085767 | 4 | 0 | BeFree |
| Osteosarcoma | 0.001085767 | 4 | 0 | BeFree |
| Thymoma | 0.001085767 | 4 | 0 | BeFree |
| Tuberculosis, Pulmonary | 0.001085767 | 4 | 0 | BeFree |
| Malignant neoplasm of testis | 0.001085767 | 4 | 0 | BeFree |
| Malignant neoplasm of lung | 0.001085767 | 4 | 0 | BeFree |
| Primary sclerosing cholangitis | 0.001085767 | 4 | 0 | BeFree |
| Hashimoto Disease | 0.001085767 | 4 | 0 | BeFree |
| Carcinoma of lung | 0.001085767 | 4 | 0 | BeFree |
| Carcinoma of bladder | 0.001085767 | 4 | 0 | BeFree |
| Inclusion Body Myopathy, Sporadic | 0.001085767 | 4 | 0 | BeFree |
| Autoimmune thyroiditis | 0.001085767 | 4 | 0 | BeFree |
| Spondylarthritis | 0.001085767 | 4 | 0 | BeFree |
| Astrocytoma | 0.000814326 | 3 | 0 | BeFree |
| Autistic Disorder | 0.000814326 | 3 | 0 | BeFree |
| Bipolar Disorder | 0.000814326 | 3 | 0 | BeFree |
| Cardiomyopathy, Dilated | 0.000814326 | 3 | 0 | BeFree |
| Choriocarcinoma | 0.000814326 | 3 | 0 | BeFree |
| Cystic Fibrosis | 0.000814326 | 3 | 0 | BeFree |
| Heart failure | 0.000814326 | 3 | 0 | BeFree |
| Hepatitis | 0.000814326 | 3 | 0 | BeFree |
| Hepatitis A | 0.000814326 | 3 | 0 | BeFree |
| Immune System Diseases | 0.000814326 | 3 | 0 | BeFree |
| Acute Promyelocytic Leukemia | 0.000814326 | 3 | 0 | BeFree |
| Liver neoplasms | 0.000814326 | 3 | 0 | BeFree |
| Myopathy | 0.000814326 | 3 | 0 | BeFree |
| Muscular Dystrophy | 0.000814326 | 3 | 0 | BeFree |
| Myocarditis | 0.000814326 | 3 | 0 | BeFree |
| Narcolepsy | 0.000814326 | 3 | 0 | BeFree |
| Ovarian Carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Pemphigus | 0.000814326 | 3 | 0 | BeFree |
| Pemphigus Vulgaris | 0.000814326 | 3 | 0 | BeFree |
| Stevens-Johnson Syndrome | 0.000814326 | 3 | 0 | BeFree |
| Uveitis | 0.000814326 | 3 | 0 | BeFree |
| Vasculitis | 0.000814326 | 3 | 0 | BeFree |
| B-Cell Lymphomas | 0.000814326 | 3 | 0 | BeFree |
| Polymyositis | 0.000814326 | 3 | 0 | BeFree |
| Cutaneous Melanoma | 0.000814326 | 3 | 0 | BeFree |
| Polyarthritis | 0.000814326 | 3 | 0 | BeFree |
| Adult type dermatomyositis | 0.000814326 | 3 | 0 | BeFree |
| Inclusion Body Myositis (disorder) | 0.000814326 | 3 | 0 | BeFree |
| Spastic syndrome | 0.000814326 | 3 | 0 | BeFree |
| Cervical Squamous Cell Carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Solid tumour | 0.000814326 | 3 | 0 | BeFree |
| Seropositive rheumatoid arthritis | 0.000814326 | 3 | 0 | BeFree |
| Hepatitis C, Chronic | 0.000814326 | 3 | 0 | BeFree |
| Toxic Shock Syndrome | 0.000814326 | 3 | 0 | BeFree |
| Diffuse panbronchiolitis | 0.000814326 | 3 | 0 | BeFree |
| Malignant neoplasm of ovary | 0.000814326 | 3 | 0 | BeFree |
| Epithelioma | 0.000814326 | 3 | 0 | BeFree |
| Renal carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Coronary Artery Disease | 0.000814326 | 3 | 0 | BeFree |
| Staphylococcal toxic shock syndrome | 0.000814326 | 3 | 0 | BeFree |
| Adenocarcinoma | 0.000542884 | 2 | 0 | BeFree |
| Alopecia Areata | 0.000542884 | 2 | 0 | BeFree |
| Aspergillosis, Allergic Bronchopulmonary | 0.000542884 | 2 | 0 | BeFree |
| Cardiovascular Diseases | 0.000542884 | 2 | 0 | BeFree |
| Colorectal Neoplasms | 0.000542884 | 2 | 0 | BeFree |
| Cowpox | 0.000542884 | 2 | 0 | BeFree |
| Dental caries | 0.000542884 | 2 | 0 | BeFree |
| Dermatomyositis | 0.000542884 | 2 | 0 | BeFree |
| Muscular Dystrophy, Duchenne | 0.000542884 | 2 | 0 | BeFree |
| Fatigue | 0.000542884 | 2 | 0 | BeFree |
| Fibrosarcoma | 0.000542884 | 2 | 0 | BeFree |
| Hematological Disease | 0.000542884 | 2 | 0 | BeFree |
| Hypothyroidism | 0.000542884 | 2 | 0 | BeFree |
| Kidney Failure, Chronic | 0.000542884 | 2 | 0 | BeFree |
| Leishmaniasis | 0.000542884 | 2 | 0 | BeFree |
| Acute lymphocytic leukemia | 0.000542884 | 2 | 0 | BeFree |
| Leukemia, Myelocytic, Acute | 0.000542884 | 2 | 0 | BeFree |
| Myeloid Leukemia | 0.000542884 | 2 | 0 | BeFree |
| Leukemia, T-Cell | 0.000542884 | 2 | 0 | BeFree |
| Lichen Planus | 0.000542884 | 2 | 0 | BeFree |
| Chronic Obstructive Airway Disease | 0.000542884 | 2 | 0 | BeFree |
| Lymphopenia | 0.000542884 | 2 | 0 | BeFree |
| Paroxysmal nocturnal hemoglobinuria | 0.000542884 | 2 | 0 | BeFree |
| Measles | 0.000542884 | 2 | 0 | BeFree |
| Mitral Valve Stenosis | 0.000542884 | 2 | 0 | BeFree |
| Mycoplasma Infections | 0.000542884 | 2 | 0 | BeFree |
| Obesity | 0.000542884 | 2 | 0 | BeFree |
| Bullous pemphigoid | 0.000542884 | 2 | 0 | BeFree |
| Periodontitis | 0.000542884 | 2 | 0 | BeFree |
| Respiratory Syncytial Virus Infections | 0.000542884 | 2 | 0 | BeFree |
| Retinoblastoma | 0.000542884 | 2 | 0 | BeFree |
| Rheumatic Heart Disease | 0.000542884 | 2 | 0 | BeFree |
| synovial sarcoma | 0.000542884 | 2 | 0 | BeFree |
| Thyroid Diseases | 0.000542884 | 2 | 0 | BeFree |
| Typhoid Fever | 0.000542884 | 2 | 1 | BeFree |
| Vascular Diseases | 0.000542884 | 2 | 0 | BeFree |
| Arthritis, Reactive | 0.000542884 | 2 | 0 | BeFree |
| Pancreatitis, Chronic | 0.000542884 | 2 | 0 | BeFree |
| Left Ventricular Hypertrophy | 0.000542884 | 2 | 0 | BeFree |
| Squamous cell carcinoma of lung | 0.000542884 | 2 | 0 | BeFree |
| Small cell carcinoma of lung | 0.000542884 | 2 | 0 | BeFree |
| Primary Sj�gren's syndrome | 0.000542884 | 2 | 0 | BeFree |
| Secondary malignant neoplasm of lung | 0.000542884 | 2 | 0 | BeFree |
| Malnutrition | 0.000542884 | 2 | 0 | BeFree |
| Aortic Aneurysm, Thoracic | 0.000542884 | 2 | 0 | BeFree |
| Teratocarcinoma | 0.000542884 | 2 | 0 | BeFree |
| Uveal melanoma | 0.000542884 | 2 | 0 | BeFree |
| X-linked agammaglobulinemia | 0.000542884 | 2 | 0 | BeFree |
| Chronic berylliosis | 0.000542884 | 2 | 0 | BeFree |
| Pemphigus and fogo selvagem | 0.000542884 | 2 | 0 | BeFree |
| Metastatic Renal Cell Cancer | 0.000542884 | 2 | 0 | BeFree |
| Metastatic melanoma | 0.000542884 | 2 | 0 | BeFree |
| Squamous cell carcinoma of esophagus | 0.000542884 | 2 | 0 | BeFree |
| Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site | 0.000542884 | 2 | 0 | BeFree |
| Immune thrombocytopenic purpura | 0.000542884 | 2 | 0 | BeFree |
| Chronic active hepatitis | 0.000542884 | 2 | 0 | BeFree |
| Hepatitis B, Chronic | 0.000542884 | 2 | 0 | BeFree |
| Malignant melanoma of eye | 0.000542884 | 2 | 0 | BeFree |
| Osteosarcoma of bone | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of kidney | 0.000542884 | 2 | 0 | BeFree |
| Idiopathic Inflammatory Myopathies | 0.000542884 | 2 | 0 | BeFree |
| Myasthenia Gravis, Autoimmune, Experimental | 0.000542884 | 2 | 0 | BeFree |
| Chronic graft-versus-host disease | 0.000542884 | 2 | 0 | BeFree |
| Alloimmunisation | 0.000542884 | 2 | 0 | BeFree |
| Squamous cell carcinoma of the head and neck | 0.000542884 | 2 | 0 | BeFree |
| Lymphocytic infiltration | 0.000542884 | 2 | 0 | BeFree |
| Precursor B-cell lymphoblastic leukemia | 0.000542884 | 2 | 0 | BeFree |
| Generalized vitiligo | 0.000542884 | 2 | 2 | BeFree |
| Cardiomyopathy, Familial Idiopathic | 0.000542884 | 2 | 0 | BeFree |
| Mammary Neoplasms | 0.000542884 | 2 | 0 | BeFree |
| Glioblastoma Multiforme | 0.000542884 | 2 | 0 | BeFree |
| Bone Sarcoma | 0.000542884 | 2 | 0 | BeFree |
| Recurrent bacterial infection | 0.000542884 | 2 | 0 | BeFree |
| Precursor Cell Lymphoblastic Leukemia Lymphoma | 0.000542884 | 2 | 0 | BeFree |
| Chronic kidney disease stage 5 | 0.000542884 | 2 | 0 | BeFree |
| Congenital adrenal hyperplasia due to 21 hydroxylase deficiency | 0.000542884 | 2 | 0 | BeFree |
| Experimental Organism Basal Cell Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Abscess | 0.000271442 | 1 | 0 | BeFree |
| Addison Disease | 0.000271442 | 1 | 0 | BeFree |
| Adrenal gland hypofunction | 0.000271442 | 1 | 0 | BeFree |
| Anemia, Pernicious | 0.000271442 | 1 | 0 | BeFree |
| Anthrax disease | 0.000271442 | 1 | 0 | BeFree |
| Melanoma, B16 | 0.000271442 | 1 | 0 | BeFree |
| Bone neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Brain Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of thyroid | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma, Transitional Cell | 0.000271442 | 1 | 0 | BeFree |
| Cholangitis, Sclerosing | 0.000271442 | 1 | 0 | BeFree |
| Hemophilia B | 0.000271442 | 1 | 0 | BeFree |
| Colonic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Demyelinating Diseases | 0.000271442 | 1 | 0 | BeFree |
| Mental Depression | 0.000271442 | 1 | 0 | BeFree |
| Depressive disorder | 0.000271442 | 1 | 0 | BeFree |
| Dermatitis Herpetiformis | 0.000271442 | 1 | 0 | BeFree |
| Dermatitis, Atopic | 0.000271442 | 1 | 0 | BeFree |
| Contact Dermatitis | 0.000271442 | 1 | 0 | BeFree |
| Eczema | 0.000271442 | 1 | 0 | BeFree |
| Toxic Epidermal Necrolysis | 0.000271442 | 1 | 0 | BeFree |
| Erysipelothrix infection | 0.000271442 | 1 | 0 | BeFree |
| Exanthema | 0.000271442 | 1 | 0 | BeFree |
| Disorder of eye | 0.000271442 | 1 | 0 | BeFree |
| Gingival Diseases | 0.000271442 | 1 | 0 | BeFree |
| Glomerulonephritis | 0.000271442 | 1 | 0 | BeFree |
| Goiter | 0.000271442 | 1 | 0 | BeFree |
| Chronic granulomatous disease | 0.000271442 | 1 | 0 | BeFree |
| Hay fever | 0.000271442 | 1 | 0 | BeFree |
| Helminthiasis | 0.000271442 | 1 | 0 | BeFree |
| Hemophilia A | 0.000271442 | 1 | 0 | BeFree |
| Hepatitis, Chronic | 0.000271442 | 1 | 0 | BeFree |
| Herpesviridae Infections | 0.000271442 | 1 | 0 | BeFree |
| Malignant histiocytosis | 0.000271442 | 1 | 0 | BeFree |
| Hodgkin Disease | 0.000271442 | 1 | 0 | BeFree |
| Hyperinsulinism | 0.000271442 | 1 | 0 | BeFree |
| Iridocyclitis | 0.000271442 | 1 | 0 | BeFree |
| Listeriosis | 0.000271442 | 1 | 0 | BeFree |
| Lupus Nephritis | 0.000271442 | 1 | 0 | BeFree |
| Reticulosarcoma | 0.000271442 | 1 | 0 | BeFree |
| Malaria, Falciparum | 0.000271442 | 1 | 0 | BeFree |
| Meleda Disease | 0.000271442 | 1 | 0 | BeFree |
| Mitral Valve Insufficiency | 0.000271442 | 1 | 0 | BeFree |
| Mixed Salivary Gland Tumor | 0.000271442 | 1 | 0 | BeFree |
| Myocardial Infarction | 0.000271442 | 1 | 0 | BeFree |
| Nephritis | 0.000271442 | 1 | 0 | BeFree |
| Osteomyelitis | 0.000271442 | 1 | 0 | BeFree |
| Pancreatic Neoplasm | 0.000271442 | 1 | 0 | BeFree |
| Pancytopenia | 0.000271442 | 1 | 0 | BeFree |
| Tropical Spastic Paraparesis | 0.000271442 | 1 | 0 | BeFree |
| Parasitic Diseases | 0.000271442 | 1 | 0 | BeFree |
| Periodontal Diseases | 0.000271442 | 1 | 0 | BeFree |
| Periodontitis, Juvenile | 0.000271442 | 1 | 0 | BeFree |
| Precancerous Conditions | 0.000271442 | 1 | 0 | BeFree |
| Pregnancy Complications | 0.000271442 | 1 | 0 | BeFree |
| Prostatic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Protein Deficiency | 0.000271442 | 1 | 0 | BeFree |
| Psychotic Disorders | 0.000271442 | 1 | 0 | BeFree |
| Pulmonary Fibrosis | 0.000271442 | 1 | 0 | BeFree |
| Henoch-Schoenlein Purpura | 0.000271442 | 1 | 0 | BeFree |
| Retinal vascular occlusion | 0.000271442 | 1 | 0 | BeFree |
| Retroviridae Infections | 0.000271442 | 1 | 0 | BeFree |
| Rhabdomyosarcoma | 0.000271442 | 1 | 0 | BeFree |
| Rosacea | 0.000271442 | 1 | 0 | BeFree |
| Dermatologic disorders | 0.000271442 | 1 | 1 | BeFree |
| Streptococcal Infections | 0.000271442 | 1 | 0 | BeFree |
| Cerebrovascular accident | 0.000271442 | 1 | 0 | BeFree |
| Giant Cell Arteritis | 0.000271442 | 1 | 0 | BeFree |
| Toxoplasmosis, Congenital | 0.000271442 | 1 | 0 | BeFree |
| Tuberous Sclerosis | 0.000271442 | 1 | 0 | BeFree |
| Immunoblastic Large-Cell Lymphoma | 0.000271442 | 1 | 0 | BeFree |
| Bronchial Hyperreactivity | 0.000271442 | 1 | 0 | BeFree |
| Polyendocrinopathies, Autoimmune | 0.000271442 | 1 | 0 | BeFree |
| Hypoplastic Left Heart Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Acute myocardial infarction | 0.000271442 | 1 | 0 | BeFree |
| Allergic asthma | 0.000271442 | 1 | 0 | BeFree |
| Liver Failure, Acute | 0.000271442 | 1 | 0 | BeFree |
| MELAS Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Adenosquamous carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Giant Cell Tumor of Bone | 0.000271442 | 1 | 0 | BeFree |
| Cervical Intraepithelial Neoplasia | 0.000271442 | 1 | 0 | BeFree |
| Hydrosalpinx (disease) | 0.000271442 | 1 | 0 | BeFree |
| Papillary thyroid carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Pemphigus Foliaceus | 0.000271442 | 1 | 0 | BeFree |
| Dermatomyositis, Childhood Type | 0.000271442 | 1 | 0 | BeFree |
| Congenital absence of adrenal gland | 0.000271442 | 1 | 0 | BeFree |
| Renal glomerular disease | 0.000271442 | 1 | 0 | BeFree |
| Impaired glucose tolerance | 0.000271442 | 1 | 0 | BeFree |
| Postpartum Thyroiditis | 0.000271442 | 1 | 0 | BeFree |
| Congenital immunodeficiency disease | 0.000271442 | 1 | 0 | BeFree |
| Severe hereditary factor VIII deficiency disease | 0.000271442 | 1 | 0 | BeFree |
| Mild hereditary factor VIII deficiency disease | 0.000271442 | 1 | 0 | BeFree |
| Coinfection | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma breast stage IV | 0.000271442 | 1 | 0 | BeFree |
| DS Stage I Plasma Cell Myeloma | 0.000271442 | 1 | 0 | BeFree |
| Squamous cell carcinoma of tonsil | 0.000271442 | 1 | 0 | BeFree |
| Iron Overload | 0.000271442 | 1 | 0 | BeFree |
| Tumor necrosis | 0.000271442 | 1 | 0 | BeFree |
| Anaplastic astrocytoma | 0.000271442 | 1 | 0 | BeFree |
| Histiocytic sarcoma | 0.000271442 | 1 | 0 | BeFree |
| Impaired cognition | 0.000271442 | 1 | 0 | BeFree |
| Iodine deficiency syndrome | 0.000271442 | 1 | 0 | BeFree |
| Hypophysitis | 0.000271442 | 1 | 0 | BeFree |
| Multiple malignancy | 0.000271442 | 1 | 0 | BeFree |
| Nonorganic psychosis | 0.000271442 | 1 | 0 | BeFree |
| Cervical intraepithelial neoplasia grade 1 | 0.000271442 | 1 | 0 | BeFree |
| Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | 0.000271442 | 1 | 0 | BeFree |
| New Variant Creutzfeldt-Jakob Disease | 0.000271442 | 1 | 0 | BeFree |
| Steroid-sensitive nephrotic syndrome | 0.000271442 | 1 | 0 | BeFree |
| Adrenal cortical hypofunction | 0.000271442 | 1 | 0 | BeFree |
| Actinic prurigo | 0.000271442 | 1 | 0 | BeFree |
| Neonatal Systemic lupus erythematosus | 0.000271442 | 1 | 0 | BeFree |
| Erythrokeratoderma | 0.000271442 | 1 | 0 | BeFree |
| Hypersensitive syndrome | 0.000271442 | 1 | 0 | BeFree |
| X-Linked Lymphoproliferative Disorder | 0.000271442 | 1 | 0 | BeFree |
| Thyroid carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Oral infection | 0.000271442 | 1 | 0 | BeFree |
| Factor V Leiden mutation | 0.000271442 | 1 | 0 | BeFree |
| lung sarcoma | 0.000271442 | 1 | 0 | BeFree |
| Monocytic leukemia | 0.000271442 | 1 | 0 | BeFree |
| Complete hydatidiform mole | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of gastrointestinal tract | 0.000271442 | 1 | 0 | BeFree |
| Acute anterior uveitis | 0.000271442 | 1 | 0 | BeFree |
| Parasitic infection | 0.000271442 | 1 | 0 | BeFree |
| Scleroderma, Limited | 0.000271442 | 1 | 0 | BeFree |
| Multiple Sclerosis, Relapsing-Remitting | 0.000271442 | 1 | 0 | BeFree |
| Lewy Body Disease | 0.000271442 | 1 | 0 | BeFree |
| Gluten sensitivity | 0.000271442 | 1 | 0 | BeFree |
| Helicobacter pylori infection | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma in situ of uterine cervix | 0.000271442 | 1 | 0 | BeFree |
| 21-hydroxylase deficiency | 0.000271442 | 1 | 0 | BeFree |
| Immunodeficiency congenital | 0.000271442 | 1 | 0 | BeFree |
| Invasive breast carcinoma | 0.000271442 | 1 | 0 | BeFree |
| latent infection | 0.000271442 | 1 | 0 | BeFree |
| Renal cancer metastatic | 0.000271442 | 1 | 0 | BeFree |
| Myasthenias | 0.000271442 | 1 | 0 | BeFree |
| Primary infection NOS | 0.000271442 | 1 | 0 | BeFree |
| West Nile viral infection | 0.000271442 | 1 | 0 | BeFree |
| Diffuse Scleroderma | 0.000271442 | 1 | 0 | BeFree |
| Persistent infection | 0.000271442 | 1 | 0 | BeFree |
| Sporadic porphyria cutanea tarda | 0.000271442 | 1 | 0 | BeFree |
| Enthesitis | 0.000271442 | 1 | 0 | BeFree |
| Inflammatory disorder | 0.000271442 | 1 | 0 | BeFree |
| Herpes simplex type 1 infection | 0.000271442 | 1 | 0 | BeFree |
| Autoimmune vasculitis | 0.000271442 | 1 | 0 | BeFree |
| Classical Hodgkin's Lymphoma | 0.000271442 | 1 | 0 | BeFree |
| Primary Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Differentiated Thyroid Gland Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Mixed Neoplasm | 0.000271442 | 1 | 0 | BeFree |
| Primary Glioblastoma | 0.000271442 | 1 | 0 | BeFree |
| Latent Tuberculosis | 0.000271442 | 1 | 0 | BeFree |
| Inflammatory polyarthritis | 0.000271442 | 1 | 0 | BeFree |
| Benign Prostatic Hyperplasia | 0.000271442 | 1 | 0 | BeFree |
| Idiopathic Pulmonary Fibrosis | 0.000271442 | 1 | 0 | BeFree |
| MAJOR AFFECTIVE DISORDER 2 | 0.000271442 | 1 | 0 | BeFree |
| MAJOR AFFECTIVE DISORDER 1 | 0.000271442 | 1 | 0 | BeFree |
| Birdshot chorioretinopathy | 0.000271442 | 1 | 0 | BeFree |
| Severe Aplastic Anemia | 0.000271442 | 1 | 0 | BeFree |
| Intravenous bisphosphonates | 0.000271442 | 1 | 0 | BeFree |
| Myocardial Failure | 0.000271442 | 1 | 0 | BeFree |
| MAJOR AFFECTIVE DISORDER 4 | 0.000271442 | 1 | 0 | BeFree |
| MAJOR AFFECTIVE DISORDER 5 | 0.000271442 | 1 | 0 | BeFree |
| MAJOR AFFECTIVE DISORDER 6 | 0.000271442 | 1 | 0 | BeFree |
| ISS Stage I Plasma Cell Myeloma | 0.000271442 | 1 | 0 | BeFree |
| Autoimmune pancreatitis | 0.000271442 | 1 | 0 | BeFree |
| Myofibrillar Myopathy | 0.000271442 | 1 | 0 | BeFree |
| MAJOR AFFECTIVE DISORDER 7 | 0.000271442 | 1 | 0 | BeFree |
| MAJOR AFFECTIVE DISORDER 8 | 0.000271442 | 1 | 0 | BeFree |
| MAJOR AFFECTIVE DISORDER 9 | 0.000271442 | 1 | 0 | BeFree |
| Juvenile dermatomyositis | 0.000271442 | 1 | 0 | BeFree |
| COMPLEMENT COMPONENT 4B DEFICIENCY | 0.000271442 | 1 | 0 | BeFree |
| Complement Component 4a Deficiency | 0.000271442 | 1 | 0 | BeFree |
| Plasmablastic lymphoma | 0.000271442 | 1 | 0 | BeFree |
| Allergic disposition | 0.000271442 | 1 | 0 | BeFree |
| AIDS (Disease) | 0.000271442 | 1 | 0 | BeFree |
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