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Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  Glycophorins A(GYPA)和B(GYPB)是人红细胞膜的主要sialoglycoproteins其承担的MN和SS血型的抗原决定簇。除了M或N和S或通常发生在所有人群小号抗原,约40相关变体的表型也已确定。这些变体包括站,以及丹徒,星期六,他,镁的Miltenberger复合和几个同种型的所有的变体,和缺失变体埃纳,S-S-U-和MK。大多数变体是GYPA和GYPB之间基因的重组的结果。 [由RefSeq的,2008年7月提供]
GYPA基因(以及对应的蛋白质)的细胞分布位置:
GYPA基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Malaria | 0.12554839 | 5 | 0 | BeFree_CTD_human_GAD |
| Skin Neoplasms | 0.120271442 | 1 | 0 | BeFree_CTD_human |
| Chronic Obstructive Airway Disease | 0.007101096 | 3 | 2 | GAD |
| Asthma | 0.004734064 | 2 | 0 | GAD |
| Crohn Disease | 0.004734064 | 2 | 0 | GAD |
| Hypertensive disease | 0.002909916 | 3 | 0 | BeFree_GAD |
| Polycythemia | 0.00272435 | 1 | 0 | LHGDN |
| Mucocutaneous Lymph Node Syndrome | 0.002367032 | 1 | 0 | GAD |
| Myocardial Infarction | 0.002367032 | 1 | 0 | GAD |
| Henoch-Schoenlein Purpura | 0.002367032 | 1 | 0 | GAD |
| Psoriasis vulgaris | 0.002367032 | 1 | 0 | GAD |
| Atopy | 0.002367032 | 1 | 0 | GAD |
| Fanconi Anemia | 0.000814326 | 3 | 0 | BeFree |
| leukemia | 0.000814326 | 3 | 0 | BeFree |
| Acute Erythroblastic Leukemia | 0.000814326 | 3 | 0 | BeFree |
| FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) | 0.000814326 | 3 | 0 | BeFree |
| Alcoholic Intoxication, Chronic | 0.000542884 | 2 | 0 | BeFree |
| Ataxia Telangiectasia | 0.000542884 | 2 | 0 | BeFree |
| Hereditary spherocytosis | 0.000542884 | 2 | 0 | BeFree |
| Vasculitis | 0.000542884 | 2 | 0 | BeFree |
| Microscopic Polyangiitis | 0.000542884 | 2 | 0 | BeFree |
| Carcinogenesis | 0.000542884 | 2 | 0 | BeFree |
| SPHEROCYTOSIS, TYPE 1 (disorder) | 0.000542884 | 2 | 0 | BeFree |
| Aplastic Anemia | 0.000271442 | 1 | 0 | BeFree |
| Cooley's anemia | 0.000271442 | 1 | 0 | BeFree |
| Bronchitis | 0.000271442 | 1 | 0 | BeFree |
| Bronchitis, Chronic | 0.000271442 | 1 | 0 | BeFree |
| Churg-Strauss Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Cockayne Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Mental Depression | 0.000271442 | 1 | 0 | BeFree |
| Depressive disorder | 0.000271442 | 1 | 0 | BeFree |
| Erythroblastosis, Fetal | 0.000271442 | 1 | 0 | BeFree |
| Graves Disease | 0.000271442 | 1 | 0 | BeFree |
| Hemoglobinopathies | 0.000271442 | 1 | 0 | BeFree |
| Acute lymphocytic leukemia | 0.000271442 | 1 | 0 | BeFree |
| Leukemia, Myelocytic, Acute | 0.000271442 | 1 | 0 | BeFree |
| Malignant hyperpyrexia due to anesthesia | 0.000271442 | 1 | 0 | BeFree |
| Paroxysmal nocturnal hemoglobinuria | 0.000271442 | 1 | 0 | BeFree |
| Polycythemia Vera | 0.000271442 | 1 | 0 | BeFree |
| Werner Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
| Ichthyosis linearis circumflexa | 0.000271442 | 1 | 0 | BeFree |
| Aspartylglucosaminuria | 0.000271442 | 1 | 0 | BeFree |
| Solid tumour | 0.000271442 | 1 | 0 | BeFree |
| Congenital disorder of glycosylation type 1A | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
| Congenital amegakaryocytic thrombocytopenia | 0.000271442 | 1 | 0 | BeFree |
| Distal Renal Tubular Acidosis | 0.000271442 | 1 | 0 | BeFree |
| FRIEDREICH ATAXIA 1 | 0.000271442 | 1 | 0 | BeFree |
| Anterior segment mesenchymal dysgenesis | 0.000271442 | 1 | 0 | BeFree |
| AXENFELD-RIEGER SYNDROME, TYPE 3 | 0.000271442 | 1 | 0 | BeFree |
| Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | 0.000271442 | 1 | 0 | BeFree |
| Deficiency of glucose-6-phosphate dehydrogenase | 0.000271442 | 1 | 0 | BeFree |
| CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Is | 0.000271442 | 1 | 0 | BeFree |
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