更多...
收起
G-protein signaling modulators (GPSMs) play diverse functional roles through their interaction with G-protein subunits. This gene encodes a receptor-independent activator of G protein signaling, which is one of several factors that influence the basal activity of G-protein signaling systems. The protein contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory (GPR) motifs in its C-terminal half. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
[中文简述(自动翻译):]  G蛋白信号调制器(GPSMs)通过与G蛋白亚基的互动玩法多样的功能角色。这个基因编码的G蛋白信号传导,这是影响G蛋白信号传导系统的基础活性的几种因素之一的受体无关的活化剂。该蛋白包含在其N-末端半7三十四肽重复序列和四G蛋白调控(GPR)在其C-末端一半图案。已发现该基因编码不同亚型多重选择性剪接转录变异体。 [由RefSeq的,2011年12月提供]
GPSM1基因(以及对应的蛋白质)的细胞分布位置:
GPSM1基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Diabetes Mellitus, Non-Insulin-Dependent | 0.12 | 1 | 1 | GWASCAT |
| Cocaine-Related Disorders | 0.12 | 1 | 0 | CTD_human |
| Bacteremia | 0.000271442 | 1 | 0 | BeFree |
| Cystic kidney | 0.000271442 | 1 | 0 | BeFree |
| Polycystic Kidney Diseases | 0.000271442 | 1 | 0 | BeFree |
| Mycoses | 0.000271442 | 1 | 0 | BeFree |
| Congenital cystic kidney disease | 0.000271442 | 1 | 0 | BeFree |
| Cystic Kidney Diseases | 0.000271442 | 1 | 0 | BeFree |
忘记密码? 点击找回密码.
扫一扫右方二维码,关注微信订阅号,实时查看信息,关注医学生物学动态。