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This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  该基因编码的蛋白质具有相似卵泡抑素,激活素结合蛋白。它包含一个FS模块,含有10个保守的半胱氨酸残基的卵泡抑素样序列。该基因产物被认为是与类风湿性关节炎相关的自身抗原。 [由RefSeq的,2008年7月提供]
FSTL1基因(以及对应的蛋白质)的细胞分布位置:
FSTL1基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Aortic Valve Insufficiency | 0.12 | 1 | 0 | CTD_human |
| Weight Gain | 0.12 | 1 | 0 | CTD_human |
| Acute kidney injury | 0.12 | 1 | 0 | CTD_human |
| Rheumatoid Arthritis | 0.005720142 | 2 | 0 | BeFree_LHGDN |
| Endometrial Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
| Malignant neoplasm of prostate | 0.002638474 | 2 | 0 | BeFree_GAD |
| Schizophrenia | 0.002367032 | 1 | 0 | GAD |
| Arthritis | 0.000542884 | 2 | 0 | BeFree |
| Myocardial Infarction | 0.000542884 | 2 | 0 | BeFree |
| Neoplasm Metastasis | 0.000542884 | 2 | 0 | BeFree |
| Degenerative polyarthritis | 0.000542884 | 2 | 0 | BeFree |
| Carcinogenesis | 0.000542884 | 2 | 0 | BeFree |
| Arthritis, Collagen-Induced | 0.000542884 | 2 | 0 | BeFree |
| Congenital Abnormality | 0.000271442 | 1 | 0 | BeFree |
| Asthma | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of endometrium | 0.000271442 | 1 | 0 | BeFree |
| Non-Small Cell Lung Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Colitis | 0.000271442 | 1 | 0 | BeFree |
| Colorectal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Fanconi Anemia | 0.000271442 | 1 | 0 | BeFree |
| Heart failure | 0.000271442 | 1 | 0 | BeFree |
| Congestive heart failure | 0.000271442 | 1 | 0 | BeFree |
| HIV Infections | 0.000271442 | 1 | 0 | BeFree |
| Ischemia | 0.000271442 | 1 | 0 | BeFree |
| Kidney Failure, Acute | 0.000271442 | 1 | 0 | BeFree |
| Ovarian Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Pleural effusion disorder | 0.000271442 | 1 | 0 | BeFree |
| Pulmonary Fibrosis | 0.000271442 | 1 | 0 | BeFree |
| Rheumatism | 0.000271442 | 1 | 0 | BeFree |
| Vascular Diseases | 0.000271442 | 1 | 0 | BeFree |
| Pleural Effusion, Malignant | 0.000271442 | 1 | 0 | BeFree |
| Adenocarcinoma of lung (disorder) | 0.000271442 | 1 | 0 | BeFree |
| Pancreatic carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of pancreas | 0.000271442 | 1 | 0 | BeFree |
| Endometrial Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Prostate carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
| Acute Coronary Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Macrophage Activation Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of ovary | 0.000271442 | 1 | 0 | BeFree |
| Inflammatory disorder | 0.000271442 | 1 | 0 | BeFree |
| Systemic onset juvenile chronic arthritis | 0.000271442 | 1 | 0 | BeFree |
| Colorectal Cancer | 0.000271442 | 1 | 0 | BeFree |
| Uterine Corpus Cancer | 0.000271442 | 1 | 0 | BeFree |
| Liver carcinoma | 0.000271442 | 1 | 0 | BeFree |
| FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) | 0.000271442 | 1 | 0 | BeFree |
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