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Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  凝血因子II受体是参与血栓形成反应的调节7-跨膜受体。蛋白水解切割导致受体的活化。 F2R是一个G蛋白偶联受体家族的成员。 [由RefSeq的,2008年7月提供]
F2R基因(以及对应的蛋白质)的细胞分布位置:
F2R基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Inflammation | 0.12272435 | 2 | 0 | CTD_human_LHGDN |
| Liver Cirrhosis | 0.12272435 | 2 | 0 | CTD_human_LHGDN |
| Fatty Liver | 0.12 | 3 | 0 | CTD_human |
| Hepatitis | 0.12 | 1 | 0 | CTD_human |
| Neoplasms, Experimental | 0.12 | 1 | 0 | CTD_human |
| Stomach Neoplasms | 0.12 | 1 | 0 | CTD_human |
| Platelet mean volume finding | 0.12 | 1 | 1 | GWASCAT |
| Hyperalgesia | 0.08272435 | 2 | 0 | LHGDN_RGD |
| Brain Ischemia | 0.08 | 1 | 0 | RGD |
| Hypertensive disease | 0.08 | 1 | 0 | RGD |
| Brain Edema | 0.08 | 1 | 0 | RGD |
| Prostatic Neoplasms | 0.011440285 | 6 | 0 | BeFree_LHGDN |
| melanoma | 0.010887469 | 12 | 0 | BeFree_LHGDN |
| Neoplasm Metastasis | 0.010324723 | 28 | 0 | BeFree_LHGDN |
| Pulmonary Fibrosis | 0.009258818 | 7 | 0 | BeFree_LHGDN |
| Myocardial Infarction | 0.005005506 | 2 | 0 | BeFree_GAD |
| Liver carcinoma | 0.00408156 | 5 | 0 | BeFree_LHGDN |
| Sepsis | 0.003538676 | 4 | 0 | BeFree_LHGDN |
| Malignant neoplasm of breast | 0.003257302 | 12 | 0 | BeFree |
| Breast Carcinoma | 0.003257302 | 12 | 0 | BeFree |
| Squamous cell carcinoma | 0.002995792 | 2 | 0 | BeFree_LHGDN |
| Colonic Neoplasms | 0.002995792 | 1 | 0 | BeFree_LHGDN |
| Endometriosis | 0.002995792 | 1 | 0 | BeFree_LHGDN |
| Pancreatic Neoplasm | 0.002995792 | 2 | 0 | BeFree_LHGDN |
| Cerebrovascular accident | 0.002995792 | 2 | 0 | BeFree_LHGDN |
| Hepatitis C, Chronic | 0.002995792 | 1 | 0 | BeFree_LHGDN |
| Coronary heart disease | 0.002909916 | 2 | 0 | BeFree_GAD |
| Encephalitis | 0.00272435 | 1 | 0 | LHGDN |
| Inflammatory Bowel Diseases | 0.00272435 | 1 | 0 | LHGDN |
| Premature Obstetric Labor | 0.00272435 | 1 | 0 | LHGDN |
| Venous Thromboembolism | 0.00272435 | 1 | 0 | LHGDN |
| Prostatic Hyperplasia | 0.00272435 | 1 | 0 | LHGDN |
| Infection | 0.00272435 | 1 | 0 | LHGDN |
| Leri-Weill dyschondrosteosis | 0.002714419 | 10 | 0 | BeFree |
| Malignant neoplasm of prostate | 0.002442977 | 9 | 0 | BeFree |
| Prostate carcinoma | 0.002442977 | 9 | 0 | BeFree |
| Cardiovascular Diseases | 0.002367032 | 1 | 0 | GAD |
| Hemorrhage | 0.002367032 | 1 | 0 | GAD |
| Premature Birth | 0.002367032 | 1 | 0 | GAD |
| Fibrinogen Adverse Event | 0.002367032 | 1 | 1 | GAD |
| Dwarfism | 0.002171535 | 8 | 0 | BeFree |
| Malignant neoplasm of stomach | 0.001900093 | 7 | 0 | BeFree |
| Stomach Carcinoma | 0.001900093 | 7 | 0 | BeFree |
| Tumor Progression | 0.001628651 | 6 | 0 | BeFree |
| Metastatic melanoma | 0.001628651 | 6 | 0 | BeFree |
| Coronary Arteriosclerosis | 0.001085767 | 4 | 0 | BeFree |
| Rheumatoid Arthritis | 0.000814326 | 3 | 0 | BeFree |
| Malignant tumor of colon | 0.000814326 | 3 | 0 | BeFree |
| Choriocarcinoma | 0.000814326 | 3 | 0 | BeFree |
| Pneumonia | 0.000814326 | 3 | 0 | BeFree |
| Schizophrenia | 0.000814326 | 3 | 3 | BeFree |
| Septicemia | 0.000814326 | 3 | 0 | BeFree |
| Turner Syndrome | 0.000814326 | 3 | 0 | BeFree |
| Pancreatic carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Malignant neoplasm of pancreas | 0.000814326 | 3 | 0 | BeFree |
| Colon Carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Idiopathic Pulmonary Fibrosis | 0.000814326 | 3 | 0 | BeFree |
| Alzheimer's Disease | 0.000542884 | 2 | 0 | BeFree |
| Refractory anemias | 0.000542884 | 2 | 0 | BeFree |
| Arteriosclerosis | 0.000542884 | 2 | 0 | BeFree |
| Atherosclerosis | 0.000542884 | 2 | 0 | BeFree |
| Blood Coagulation Disorders | 0.000542884 | 2 | 0 | BeFree |
| Renal Cell Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Colorectal Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| leukemia | 0.000542884 | 2 | 0 | BeFree |
| Chronic Lymphocytic Leukemia | 0.000542884 | 2 | 0 | BeFree |
| Leukemia, Myelocytic, Acute | 0.000542884 | 2 | 0 | BeFree |
| Chronic Obstructive Airway Disease | 0.000542884 | 2 | 1 | BeFree |
| Lung Neoplasms | 0.000542884 | 2 | 0 | BeFree |
| Myocarditis | 0.000542884 | 2 | 0 | BeFree |
| Prader-Willi Syndrome | 0.000542884 | 2 | 0 | BeFree |
| Pulmonary Edema | 0.000542884 | 2 | 0 | BeFree |
| Virus Diseases | 0.000542884 | 2 | 0 | BeFree |
| Idiopathic pulmonary hypertension | 0.000542884 | 2 | 0 | BeFree |
| Madelung Deformity | 0.000542884 | 2 | 0 | BeFree |
| Fibrosis, Liver | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of lung | 0.000542884 | 2 | 0 | BeFree |
| Proliferative vitreoretinopathy | 0.000542884 | 2 | 0 | BeFree |
| Cholestasis of pregnancy | 0.000542884 | 2 | 0 | BeFree |
| Restenosis | 0.000542884 | 2 | 0 | BeFree |
| Adenoma of lung | 0.000542884 | 2 | 0 | BeFree |
| Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | 0.000542884 | 2 | 0 | BeFree |
| Chronic rejection of renal transplant | 0.000542884 | 2 | 0 | BeFree |
| Langer Mesomelic Dysplasia Syndrome | 0.000542884 | 2 | 0 | BeFree |
| Carcinogenesis | 0.000542884 | 2 | 0 | BeFree |
| Epithelial ovarian cancer | 0.000542884 | 2 | 0 | BeFree |
| Carcinoma of lung | 0.000542884 | 2 | 0 | BeFree |
| Secondary malignant neoplasm of lymph node | 0.000542884 | 2 | 0 | BeFree |
| 5q-syndrome | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of kidney | 0.000542884 | 2 | 0 | BeFree |
| Malignant Pleural Mesothelioma | 0.000542884 | 2 | 0 | BeFree |
| Invasive breast carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Ischemic stroke | 0.000542884 | 2 | 0 | BeFree |
| Myelodysplastic Syndrome with Isolated del(5q) | 0.000542884 | 2 | 0 | BeFree |
| Epithelioma | 0.000542884 | 2 | 0 | BeFree |
| Renal carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Colorectal Cancer | 0.000542884 | 2 | 0 | BeFree |
| Benign Prostatic Hyperplasia | 0.000542884 | 2 | 0 | BeFree |
| Severe Sepsis | 0.000542884 | 2 | 0 | BeFree |
| Chromosome 5, trisomy 5q | 0.000542884 | 2 | 0 | BeFree |
| Coronary Artery Disease | 0.000542884 | 2 | 0 | BeFree |
| Refractory anemia, without ringed sideroblasts, without excess blasts | 0.000542884 | 2 | 0 | BeFree |
| Idiopathic pulmonary arterial hypertension | 0.000542884 | 2 | 0 | BeFree |
| Ischemic Cerebrovascular Accident | 0.000542884 | 2 | 0 | BeFree |
| Congenital Abnormality | 0.000271442 | 1 | 0 | BeFree |
| Asthma | 0.000271442 | 1 | 0 | BeFree |
| Autoimmune Diseases | 0.000271442 | 1 | 0 | BeFree |
| Bone Marrow Diseases | 0.000271442 | 1 | 0 | BeFree |
| Borderline Personality Disorder | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of endometrium | 0.000271442 | 1 | 0 | BeFree |
| Non-Small Cell Lung Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Carcinosarcoma | 0.000271442 | 1 | 0 | BeFree |
| Cerebral Infarction | 0.000271442 | 1 | 0 | BeFree |
| Cholestasis | 0.000271442 | 1 | 0 | BeFree |
| Congenital chromosomal disease | 0.000271442 | 1 | 0 | BeFree |
| Coronary Thrombosis | 0.000271442 | 1 | 0 | BeFree |
| Mental Depression | 0.000271442 | 1 | 0 | BeFree |
| Depressive disorder | 0.000271442 | 1 | 0 | BeFree |
| Gastroesophageal reflux disease | 0.000271442 | 1 | 0 | BeFree |
| Glioblastoma | 0.000271442 | 1 | 0 | BeFree |
| Glioma | 0.000271442 | 1 | 0 | BeFree |
| Hepatitis C | 0.000271442 | 1 | 0 | BeFree |
| HIV Infections | 0.000271442 | 1 | 0 | BeFree |
| Hypoglycemia | 0.000271442 | 1 | 0 | BeFree |
| Immunologic Deficiency Syndromes | 0.000271442 | 1 | 0 | BeFree |
| Influenza | 0.000271442 | 1 | 0 | BeFree |
| Ischemia | 0.000271442 | 1 | 0 | BeFree |
| Keloid | 0.000271442 | 1 | 0 | BeFree |
| Leishmaniasis | 0.000271442 | 1 | 0 | BeFree |
| Liver neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Lung diseases | 0.000271442 | 1 | 0 | BeFree |
| Lupus Erythematosus, Systemic | 0.000271442 | 1 | 0 | BeFree |
| Medulloblastoma | 0.000271442 | 1 | 0 | BeFree |
| Mesothelioma | 0.000271442 | 1 | 0 | BeFree |
| Degenerative polyarthritis | 0.000271442 | 1 | 0 | BeFree |
| Ovarian Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Parkinson Disease | 0.000271442 | 1 | 0 | BeFree |
| Peutz-Jeghers Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Pulmonary Emphysema | 0.000271442 | 1 | 0 | BeFree |
| Rhabdomyosarcoma | 0.000271442 | 1 | 0 | BeFree |
| Systemic Scleroderma | 0.000271442 | 1 | 0 | BeFree |
| Spinal Cord Diseases | 0.000271442 | 1 | 0 | BeFree |
| Hermanski-Pudlak Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Polyendocrinopathies, Autoimmune | 0.000271442 | 1 | 0 | BeFree |
| Squamous cell carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
| Arterial thrombosis | 0.000271442 | 1 | 0 | BeFree |
| Lingual-Facial-Buccal Dyskinesia | 0.000271442 | 1 | 0 | BeFree |
| Cicatrix, Hypertrophic | 0.000271442 | 1 | 0 | BeFree |
| Cholangiocarcinoma | 0.000271442 | 1 | 0 | BeFree |
| Carotid artery occlusion | 0.000271442 | 1 | 0 | BeFree |
| Squamous cell carcinoma of esophagus | 0.000271442 | 1 | 0 | BeFree |
| Adenocarcinoma Of Esophagus | 0.000271442 | 1 | 0 | BeFree |
| Vascular Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Adenocarcinoma of colon | 0.000271442 | 1 | 0 | BeFree |
| Helicobacter-associated gastritis | 0.000271442 | 1 | 0 | BeFree |
| Idiopathic crescentic glomerulonephritis | 0.000271442 | 1 | 0 | BeFree |
| Nephrotic range proteinuria | 0.000271442 | 1 | 0 | BeFree |
| Endometrial Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Sleep Apnea, Obstructive | 0.000271442 | 1 | 0 | BeFree |
| Recurrent tumor | 0.000271442 | 1 | 0 | BeFree |
| Leukemogenesis | 0.000271442 | 1 | 0 | BeFree |
| Tardive Dyskinesia | 0.000271442 | 1 | 0 | BeFree |
| Poorly differentiated carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Cholestasis, chronic | 0.000271442 | 1 | 0 | BeFree |
| gastritis h pylori | 0.000271442 | 1 | 0 | BeFree |
| Helicobacter pylori infection | 0.000271442 | 1 | 0 | BeFree |
| Rhabdoid Tumor of the Kidney | 0.000271442 | 1 | 0 | BeFree |
| Cholestatic liver disease | 0.000271442 | 1 | 0 | BeFree |
| Cerebral Ischemia | 0.000271442 | 1 | 0 | BeFree |
| Squamous cell carcinoma of the head and neck | 0.000271442 | 1 | 0 | BeFree |
| Attention deficit hyperactivity disorder | 0.000271442 | 1 | 0 | BeFree |
| Precursor B-cell lymphoblastic leukemia | 0.000271442 | 1 | 0 | BeFree |
| Partial Trisomy | 0.000271442 | 1 | 0 | BeFree |
| Adenocarcinoma of large intestine | 0.000271442 | 1 | 0 | BeFree |
| Tumor Angiogenesis | 0.000271442 | 1 | 0 | BeFree |
| OVERLAP CONNECTIVE TISSUE DISEASE | 0.000271442 | 1 | 0 | BeFree |
| Uterine Corpus Cancer | 0.000271442 | 1 | 0 | BeFree |
| Chronic thromboembolic pulmonary hypertension | 0.000271442 | 1 | 0 | BeFree |
| Thyroid Hormone Resistance Syndrome | 0.000271442 | 1 | 0 | BeFree |
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