DCTN3(dynactin 3 (p22)) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

9p13
基因染色体位置图

基因简述

基因简述

This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

[中文简述(自动翻译):]  该基因编码dynactin最小的亚单位，包括10个亚基22?150 kD的大小不等的大分子复合物。 Dynactin同时结合微管和胞质动力蛋白。它参与的细胞功能，包括ER到高尔基体转运，溶酶体和内涵体的心运动，纺锤体形成，胞质分裂，染色体运动，核的定位，并axonogenesis一个多样化。此亚基，像大多数其他dynactin亚基，只存在作为dynactin复杂的一部分。它主要是α-螺旋的蛋白质具有非常小的卷曲螺旋，和直接结合到最大亚基（P150）dynactin的。选择性剪接结果在多个抄本变形。 [由RefSeq的，2013年7月提供]

OMIM数据库中对DCTN3基因的介绍     Wikipedia数据库中对DCTN3基因的介绍

基因序列

基因序列

DCTN3基因的碱基序列：[NCBI]

基因突变

基因突变

DCTN3基因的碱基突变：           显示全部snp
rs1802447       rs57700593       rs111318467       rs112048809       rs113039529       rs139666728       rs150997798       rs181356165       rs183997075       rs184140944       rs188907222       rs189114285       rs193043882       rs201579471       rs370343791       rs370374770       rs528051881       rs528971296       rs535462074       rs546164183       rs550305018       rs553411716       rs555105097       rs563445296       rs574045361       rs745585313       rs746473932       rs747055794       rs747784894       rs749724188       rs750363142       rs750404732       rs751688962       rs752943124       rs753714194       rs754788515       rs755946611      
rs756631817       rs757212302       rs758460702       rs759882419       rs760100150       rs761939455       rs763237857       rs763283932       rs764343777       rs765619518       rs767648819       rs768357981       rs769628014       rs770129227       rs770385074       rs771613938       rs774991060       rs775834355       rs775948526       rs777058343       rs777339270       rs777840116       rs779633149       rs779805494       rs779904936       rs781088068       rs3802427       rs3808869       rs3808870       rs7864478       rs7865283       rs10814127       rs10972167       rs10972168       rs10972169       rs10972170       rs10972171       rs10972172       rs12335475       rs12337871       rs12352811       rs13285145       rs35159161       rs35250995       rs35734048       rs36024608       rs57386918       rs73497065       rs74324688       rs74774311       rs75929392       rs76093916       rs76596417       rs77504698       rs79068011       rs79394690       rs79397329       rs80113058       rs111318175       rs111454615       rs111707496       rs112093827       rs113002200       rs113366398       rs113633518       rs113648203       rs113752160       rs114005165       rs114192026       rs116001123       rs116485066       rs116919410       rs137987322       rs138550382       rs138685160       rs138699024       rs138916991       rs139337175       rs139780416       rs140055575       rs140351646       rs140417025       rs140797141       rs141163586       rs142117125       rs142544785       rs142710890       rs143348098       rs143451853       rs143551370       rs143903559       rs144108229       rs144769273       rs145476640       rs146137441       rs146141185       rs146319245       rs146760873       rs146800117       rs147505196       rs147528162       rs147594403       rs148006007       rs148846062       rs148865762       rs149602566       rs149666088       rs149771118       rs150083158       rs150189522       rs150314400       rs150631162       rs180916226       rs181208308       rs182041904       rs182852524       rs182934094       rs184220309       rs184628839       rs185852107       rs187128790       rs187195808       rs187526519       rs188387694       rs188641986       rs190107919       rs190614569       rs192134841       rs192422971       rs199739092       rs199820143       rs200075015       rs200211070       rs200578089       rs201191420       rs201672788       rs201976373       rs367651208       rs367678842       rs367782478       rs367852617       rs368172269       rs368248766       rs368315184       rs368744031       rs368817768       rs369359140       rs369731428       rs370090780       rs371040951       rs371140674       rs371196847       rs371404822       rs371671327       rs372180175       rs372272571       rs372285847       rs373685361       rs373692568       rs373744786       rs374081381       rs375071063       rs375128324       rs375521862       rs375535845       rs375611227       rs376039967       rs376673463       rs376819892       rs376884875       rs377763085       rs527456947       rs527883241       rs528650415       rs528829993       rs529038758       rs529213035       rs529408280       rs530345919       rs531117817       rs531781261       rs532789539       rs532890244       rs533116086       rs533146549       rs533820239       rs533885945       rs534629059       rs534866349       rs534925689       rs535035323       rs535690158       rs535756203       rs536091707       rs536141970       rs537609931       rs537620651       rs537883457       rs538206625       rs538502988       rs539045172       rs539145587       rs540834516       rs540951087       rs541085590       rs541149088       rs542034444       rs542266902       rs542399861       rs543031231       rs543431664       rs543642739       rs543843193       rs543911438       rs544200790       rs544723075       rs545404593       rs546123991       rs546359028       rs546523036       rs548340379       rs548343069       rs548403576       rs549510286       rs550517329       rs551004314       rs551152965       rs551207004       rs551228728       rs551805981       rs552008281       rs552140632       rs552408188       rs552658205       rs552756625       rs552818010       rs553387283       rs554534758       rs554558789       rs555742426       rs556543161       rs557194673       rs557259994       rs557801494       rs558063289       rs558111189       rs558264110       rs558395726       rs558504728       rs558708218       rs558930333       rs559054192       rs560735035       rs560735364       rs561829537       rs561871455       rs561891576       rs562850397       rs563083593       rs563348746       rs563374110       rs564136773       rs564143226       rs564150895       rs564208132       rs564726602       rs565559616       rs566406630       rs566948538       rs567756497       rs567769871       rs567803883       rs568136188       rs568204707       rs568918130       rs569181270       rs569588643       rs570440921       rs571595095       rs571645079       rs572197625       rs572259404       rs572603636       rs572652603       rs573772548       rs574440390       rs575293377       rs575294292       rs575554537       rs577789431       rs577857970       rs577997212       rs578025446       rs578239969       rs745431861       rs745521294       rs745541553       rs745606027       rs745643006       rs745751782       rs745803356       rs745922222       rs746015858       rs746110493       rs746372465       rs746571703       rs746677927       rs746731787       rs746754046       rs746796486       rs746843867       rs747151774       rs747206066       rs747354907       rs747554692       rs747558019       rs748000904       rs748090681       rs748464749       rs748492999       rs748700711       rs748874888       rs748960366       rs749257764       rs749341078       rs749369766       rs749383965       rs749400628       rs749630657       rs749810199       rs749985704       rs750535086       rs750672288       rs750717777       rs750781585       rs751302505       rs751514339       rs751602699       rs752277002       rs752467729       rs752470757       rs752733729       rs752819587       rs753131223       rs753233974       rs753319591       rs753356230       rs753814169       rs753822509       rs753987952       rs754384791       rs754499336       rs754608463       rs754696482       rs755043846       rs755080004       rs755360360       rs755449170       rs755450027       rs755503270       rs755589080       rs755857990       rs756206053       rs756227110       rs756342392       rs756428229       rs756721159       rs756756195       rs756990888       rs757078777       rs757245618       rs757486162       rs757694860       rs757784721       rs757840840       rs758005005       rs758008889       rs758350530       rs758352558       rs758774538       rs758856591       rs758882411       rs759061752       rs759087517       rs759374476       rs759546479       rs759636426       rs759692940       rs759794001       rs759832725       rs759892596       rs760156708       rs760196604       rs760647125       rs760722293       rs760812117       rs760875893       rs761647683       rs762013693       rs762029220       rs762153272       rs762265867       rs762353711       rs762529769       rs762537308       rs762867928       rs763545339       rs763813007       rs763875713       rs764165942       rs764253472       rs764547264       rs764610261       rs764644821       rs764757809       rs764953808       rs765006029       rs765133283       rs765213156       rs765223267       rs765305108       rs765479738       rs765886984       rs766278824       rs766355757       rs766366712       rs766379551       rs766491283       rs766579110       rs766687973       rs766778152       rs766854400       rs766997234       rs767461694       rs767596161       rs767832974       rs767910203       rs768002313       rs768088472       rs768270189       rs768526563       rs768597848       rs768906077       rs769085525       rs769363969       rs769535770       rs769661488       rs769724790       rs769895964       rs769983999       rs770247400       rs770267296       rs770448177       rs770535946       rs770753091       rs770810056       rs771028918       rs771077800       rs771113083       rs771929551       rs772060854       rs772318502       rs772383929       rs772678031       rs772747146       rs772754303       rs772842236       rs772844336       rs772932947       rs773018642       rs773185324       rs773273733       rs773274648       rs773362386       rs773753445       rs773939545       rs773984068       rs774038865       rs774436674       rs774536412       rs774539539       rs774731149       rs774799784       rs775074270       rs775200086       rs775494615       rs775657370       rs775682220       rs775767828       rs775935933       rs776024329       rs776226346       rs776569402       rs776702143       rs776704881       rs776790598       rs777181060       rs777372990       rs777566433       rs777655099       rs777752216       rs778000817       rs778020216       rs778337990       rs778682603       rs779054301       rs779179016       rs779368766       rs779461928       rs779822792       rs779912731       rs779944241       rs780028461       rs780218650       rs780302600       rs780419837       rs780599736       rs780705005       rs780794844       rs780983211       rs781450566       rs781536152       rs781540208       rs781624193       rs781751202      

基因表达

基因表达

DCTN3基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AATTCATCCTAGCAGCCGT
59
TGGACTCCTCAGTGATTTCC
59
TGGATCCTGAGTACATCGAC
59
GGATAAACTGCTCCTCTGCT
60
GGGAGAGGGTGAAGATTCTC
59
GATGTACTCAGGATCCAGGT
58
AGATCCACATTCAGCAGCA
59
TATTCCTCCAGGAGAGCCT
59
CAACAAGACTACAATGCTTCTC
58
AGCTATCACTCCTCTGCTG
59
GATTGAAGATCTGATCAAGTACCTG
59
TAAACTGCTCCTCTGCTAGG
58
AGCAGCAGATTCCTATTCTC
57
CTAGCTGGCAAAGTAGCTC
58
AGATCCACATTCAGCAGCA
59
GTATTCCTCCAGGAGAGCC
59
CCTGGATCCTGAGTACATCG
60
ATAAACTGCTCCTCTGCTAGG
59
GATTGAAGATCTGATCAAGTACCTG
59
TAGAGGCATCAGGTATGGC
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

DCTN3基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

DCTN3基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000086
O75935(UniProtKB)
TAS
GO:0000777
O75935(UniProtKB)
IEA
GO:0000910
O75935(UniProtKB)
IDA
GO:0005198
O75935(UniProtKB)
TAS
GO:0005515
O75935(UniProtKB)
IPI
GO:0005813
O75935(UniProtKB)
IDA
GO:0005819
O75935(UniProtKB)
IEA
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005829
O75935(UniProtKB)
TAS
GO:0005869
O75935(UniProtKB)
IPI
GO:0006888
O75935(UniProtKB)
TAS
GO:0007017
O75935(UniProtKB)
IEA
GO:0007067
O75935(UniProtKB)
IEA
GO:0019886
O75935(UniProtKB)
TAS
GO:0030496
O75935(UniProtKB)
IEA
GO:0032154
O75935(UniProtKB)
IEA
GO:0048471
O75935(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控DCTN3基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Lyme Disease 0.000542884 2 0 BeFree
Acute Disease 0.000271442 1 0 BeFree
Foot-and-Mouth Disease 0.000271442 1 0 BeFree
Bullous pemphigoid 0.000271442 1 0 BeFree
Medullary carcinoma of thyroid 0.000271442 1 0 BeFree
Chronic non-A non-B hepatitis 0.000271442 1 0 BeFree
Lyme Arthritis 0.000271442 1 0 BeFree
Solid tumour 0.000271442 1 0 BeFree
Triploidy syndrome 0.000271442 1 0 BeFree
Ocular albinism, type I 0.000271442 1 0 BeFree
Sleep Apnea, Obstructive 0.000271442 1 0 BeFree
Liver carcinoma 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

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基因相关服务

基因相关服务

基因评论

基因评论

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