CXCL2基因详情-基因数据库-基因云馆

CXCL2(chemokine (C-X-C motif) ligand 2) 转至新版数据库

基因简称(symbol)

CXCL2 [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

SCYB2|GROb|MIP-2a|MGSA-b|CINC-2a

基因家族代码(gene_family_id)

483|542 [HGNC] [GenScript]

omim代码

139110

entrez码

2920 [Vega]

vega基因码

ensembl基因码

ENSG00000081041 [Ensembl]

基因家族(gene family)

Chemokine ligands|Endogenous ligands

refseq数据库代号

NM_002089

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

04q13.3

同源基因名称(alias name)

基因名称批准使用时间(date_approved_reserved)

1991-05-21T00:00:00Z

基因简称更名时间(date_symbol_changed)

2002-08-23T00:00:00Z

基因名称更名时间(date_name_changed)

2002-08-22T00:00:00Z

更新时间(date_modified)

2014-11-19T00:00:00Z

ucsc码

uc003hhm.4

ena

M36820

ccds数据码

CCDS34008

uniprot数据码

P19875

pubmed代码

2217207

mgd码

MGI:108068

rgd码

RGD:619869

生命科学数据库(lsdb)

更新时间(date modified)

2014-11-19T00:00:00Z

cosmic

CXCL2

mirbase

基因曾用简称(prev symbol)

GRO2

基因曾用名称(prev name)

GRO2 oncogene

homeodb

cosmic

CXCL2

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

4q13.3

This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation. [provided by RefSeq, Sep 2014]

[中文简述(自动翻译):] 此抗微生物基因是编码参与免疫调节和炎症过程分泌蛋白质趋化因子超家族的一部分。该超家族分为基于成熟的肽的N末端半胱氨酸残基的排列四个亚科。该趋化因子，该趋亚科的成员，在炎症位点表达，并且可以抑制造血祖细胞增殖。 [由RefSeq的，2014年9月提供]

OMIM数据库中对CXCL2基因的介绍 Wikipedia数据库中对CXCL2基因的介绍

CXCL2基因的碱基序列：[NCBI]

CXCL2基因的碱基突变：显示全部snp

rs9131 rs1837558 rs3806792 rs6832638 rs11574447 rs11574448 rs11574449 rs33950486 rs76647288 rs79896708 rs113025589 rs113065419 rs113885913 rs114657535 rs115904713 rs116669388 rs138237300 rs138833367 rs142264518 rs142728560 rs142917006 rs143367714 rs144050343 rs144967766 rs145848689 rs146575633 rs148727820 rs149053885 rs149374930 rs150188732 rs151297331 rs182728074 rs183034978 rs183137629 rs184498134 rs185575241 rs185915464

rs187336485 rs187721591 rs187746218 rs188069556 rs188944956 rs189458219 rs190679442 rs192055291 rs192384200 rs192646538 rs199529315 rs199778373 rs199782155 rs199812891 rs199820237 rs199906828 rs200214601 rs200356891 rs200413892 rs200648627 rs200663834 rs200793450 rs200873298 rs200911424 rs200931429 rs200989587 rs200992030 rs201100927 rs201152585 rs201218927 rs201552328 rs201597863 rs201616184 rs201739633 rs201836008 rs201970650 rs202120861 rs367903952 rs368146276 rs368385936 rs370299459 rs370906034 rs371227293 rs371945474 rs372337678 rs374705558 rs374968834 rs377663383 rs377707814 rs397787596 rs527700880 rs529468957 rs529604595 rs530259472 rs530508516 rs531375464 rs532816265 rs535488364 rs535688673 rs536665589 rs537309877 rs538428386 rs538461014 rs539036219 rs540893185 rs541291600 rs542273464 rs543091188 rs543482030 rs543636389 rs544282338 rs545653854 rs545654624 rs547624876 rs548396262 rs548742686 rs550626661 rs550665314 rs551284482 rs553316318 rs553596447 rs555388358 rs555611934 rs556237137 rs557377494 rs558299246 rs559088923 rs559241204 rs559300363 rs560175417 rs560479875 rs560549957 rs561874420 rs563893118 rs564428100 rs564762931 rs565434121 rs565467248 rs565789585 rs567834840 rs568060950 rs568600856 rs569597048 rs569675634 rs571020474 rs571262835 rs571434555 rs571712244 rs571852177 rs574320648 rs574512322 rs575971969 rs576357389 rs576496626 rs746075939 rs746161349 rs747221629 rs747593102 rs748528541 rs748738093 rs748937638 rs749242569 rs749310499 rs750117850 rs750947723 rs751478943 rs752061063 rs752706721 rs752933462 rs753741502 rs754490441 rs754644763 rs755085970 rs755316953 rs755525541 rs756460806 rs757065479 rs757118828 rs757336342 rs758008188 rs758110362 rs758430569 rs758440195 rs758998062 rs759391615 rs760397923 rs760413015 rs760962805 rs761826681 rs762044384 rs762380109 rs763155248 rs763597331 rs764022735 rs764546623 rs764651890 rs765461293 rs767011385 rs767415288 rs767468602 rs767969307 rs768414876 rs769226365 rs769433487 rs769965449 rs770759328 rs771004099 rs771258965 rs771730846 rs771936739 rs772692101 rs773261820 rs773598787 rs774070216 rs774403935 rs775002602 rs775008091 rs775126279 rs775781780 rs777667311 rs777759075 rs778295766 rs778719789 rs778748849 rs778838611 rs778843350 rs779089045 rs779584893 rs779690676 rs780318567 rs780434409 rs781608529

CXCL2基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

AAGTGTGAAGGTGAAGTCC

57

CGAGACTTACATGACTTCGG

58

GAATTCACCTCAAGAACATCCA

59

AGTGTGGCTATGACTTCGG

60

CTCAAGAACATCCAAAGTGTG

58

ATTCTTGAGTGTGGCTATGAC

58

CTCAAGAACATCCAAAGTGTG

58

ATTCTTGAGTGTGGCTATGAC

58

ACCTCAAGAACATCCAAAGTG

59

TTCTTGAGTGTGGCTATGAC

58

CCAAAGTGTGAAGGTGAAGTC

60

GACTTACATGACTTCGGTTTGG

60

ACCTCAAGAACATCCAAAGTG

59

TTCTTGAGTGTGGCTATGAC

58

ACATCCAAAGTGTGAAGGTG

58

TACATGACTTCGGTTTGGG

58

GAATTCACCTCAAGAACATCCA

59

AGTGTGGCTATGACTTCGG

60

尚未收录相关数据

CXCL2基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

CXCL2基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0002237

P19875(UniProtKB)

IDA

GO:0005515

P19875(UniProtKB)

IPI

GO:0005515

P19875(UniProtKB)

IPI

GO:0005576

P19875(UniProtKB)

TAS

GO:0005576

P19875(UniProtKB)

TAS

GO:0005576

P19875(UniProtKB)

TAS

GO:0005576

P19875(UniProtKB)

TAS

GO:0005615

P19875(UniProtKB)

IEA

GO:0006935

P19875(UniProtKB)

TAS

GO:0006954

P19875(UniProtKB)

IEA

GO:0006955

P19875(UniProtKB)

IBA

GO:0007186

P19875(UniProtKB)

IBA

GO:0008009

P19875(UniProtKB)

IEA

GO:0032496

P19875(UniProtKB)

IBA

GO:0042127

P19875(UniProtKB)

IBA

GO:0045236

P19875(UniProtKB)

IBA

GO:0060326

P19875(UniProtKB)

IEA

GO:0070098

P19875(UniProtKB)

IBA

GO:0090023

P19875(UniProtKB)

IBA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控CXCL2基因的相关microRNA：

hsa-miR-1 hsa-miR-335 hsa-miR-98

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Reperfusion Injury	0.2	4	0	CTD_human_RGD
Mammary Neoplasms	0.12272435	2	0	CTD_human_LHGDN
Degenerative polyarthritis	0.120542884	2	0	BeFree_CTD_human
Rheumatoid Arthritis	0.12	1	0	CTD_human
Bone Resorption	0.12	1	0	CTD_human
Cholestasis	0.12	1	0	CTD_human
Esophageal Neoplasms	0.12	1	0	CTD_human
Heart failure	0.12	1	0	CTD_human
Hypertensive disease	0.12	1	0	CTD_human
Inflammation	0.12	1	0	CTD_human
Pulmonary Fibrosis	0.12	1	0	CTD_human
Shock, Hemorrhagic	0.12	1	0	CTD_human
Dermatologic disorders	0.12	1	0	CTD_human
Myocardial Ischemia	0.12	1	0	CTD_human
Dermatitis, Allergic Contact	0.12	1	0	CTD_human
Arsenic Poisoning	0.12	1	0	CTD_human
Infarction, Middle Cerebral Artery	0.12	1	0	CTD_human
Pneumonia	0.080542884	3	0	BeFree_RGD
Lung diseases	0.080271442	6	0	BeFree_RGD
Pneumonia, Bacterial	0.08	1	0	RGD
Intrahepatic Cholestasis	0.08	1	0	RGD
Hemorrhage	0.08	1	0	RGD
Hepatitis, Animal	0.08	1	0	RGD
Alcoholic Liver Diseases	0.08	1	0	RGD
Myocardial Reperfusion Injury	0.08	1	0	RGD
Periodontitis	0.08	1	0	RGD
Pleurisy	0.08	1	0	RGD
Aspiration Pneumonia	0.08	1	0	RGD
Pneumonia, Viral	0.08	1	0	RGD
Coronavirus Infections	0.08	1	0	RGD
Acute Lung Injury	0.08	1	0	RGD
Pancreatitis, Acute Necrotizing	0.08	1	0	RGD
Brain Edema	0.08	1	0	RGD
Sepsis	0.008001298	2	0	BeFree_GAD_LHGDN
Neoplasm Metastasis	0.003267234	3	0	BeFree_LHGDN
Glycogen Storage Disease	0.00272435	1	0	LHGDN
Asthma	0.002367032	1	0	GAD
Bronchiolitis, Viral	0.002367032	1	0	GAD
HIV Infections	0.002367032	1	0	GAD
Respiratory Syncytial Virus Infections	0.002367032	1	0	GAD
melanoma	0.000814326	3	0	BeFree
Mycoses	0.000542884	2	0	BeFree
Septicemia	0.000542884	2	0	BeFree
Severe Sepsis	0.000542884	2	0	BeFree
Acanthamoeba Keratitis	0.000271442	1	0	BeFree
Carcinoma, Transitional Cell	0.000271442	1	0	BeFree
Colitis	0.000271442	1	0	BeFree
Dermatitis, Atopic	0.000271442	1	0	BeFree
Shigella Infections	0.000271442	1	0	BeFree
Eczema	0.000271442	1	0	BeFree
Glioma	0.000271442	1	0	BeFree
Hepatitis	0.000271442	1	0	BeFree
Hepatitis A	0.000271442	1	0	BeFree
Influenza	0.000271442	1	0	BeFree
Ischemia	0.000271442	1	0	BeFree
Liver diseases	0.000271442	1	0	BeFree
Multiple Sclerosis	0.000271442	1	0	BeFree
Obesity	0.000271442	1	0	BeFree
Osteoporosis	0.000271442	1	0	BeFree
Pulmonary Edema	0.000271442	1	0	BeFree
Virus Diseases	0.000271442	1	0	BeFree
Systemic candidiasis	0.000271442	1	0	BeFree
Cholangiocarcinoma	0.000271442	1	0	BeFree
Gastrointestinal Stromal Tumors	0.000271442	1	0	BeFree
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site	0.000271442	1	0	BeFree
Prosthetic joint infection	0.000271442	1	0	BeFree
Acute pyelonephritis	0.000271442	1	0	BeFree
Carcinogenesis	0.000271442	1	0	BeFree
Retinoic acid syndrome	0.000271442	1	0	BeFree
Infectious disease of lung	0.000271442	1	0	BeFree
Urothelial Carcinoma	0.000271442	1	0	BeFree
Liver carcinoma	0.000271442	1	0	BeFree
Gastrointestinal Stromal Sarcoma	0.000271442	1	0	BeFree
Neutrophilia (disorder)	0.000271442	1	0	BeFree