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The protein encoded by this gene belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. This gene is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  由该基因编码的蛋白质属于家庭细胞质接头蛋白,其已经被提出来介导特定膜细胞器和微管之间的相互作用。这种蛋白质被发现与两个微管和称为树突板层小体的细胞器相关联。此基因在威廉斯综合征,在7q11.23引起邻接基因的缺失一种多系统发育障碍hemizygously删除。该基因的可变剪接产生2转录变异体。 [由RefSeq的,2008年7月提供]
CLIP2基因(以及对应的蛋白质)的细胞分布位置:
CLIP2基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Williams Syndrome | 0.201900093 | 7 | 0 | BeFree_MGD_ORPHANET |
| Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
| Autistic Disorder | 0.000542884 | 2 | 0 | BeFree |
| Diabetes Mellitus, Insulin-Dependent | 0.000542884 | 2 | 0 | BeFree |
| Hepatitis C | 0.000542884 | 2 | 0 | BeFree |
| Primary Effusion Lymphoma | 0.000542884 | 2 | 0 | BeFree |
| Amyotrophic Lateral Sclerosis | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of breast | 0.000271442 | 1 | 0 | BeFree |
| Diabetes | 0.000271442 | 1 | 0 | BeFree |
| Diabetes Mellitus | 0.000271442 | 1 | 0 | BeFree |
| Diabetes Mellitus, Non-Insulin-Dependent | 0.000271442 | 1 | 0 | BeFree |
| Hepatitis B | 0.000271442 | 1 | 0 | BeFree |
| Hyperglycemia | 0.000271442 | 1 | 0 | BeFree |
| Malaria | 0.000271442 | 1 | 0 | BeFree |
| Kaposi Sarcoma | 0.000271442 | 1 | 0 | BeFree |
| Polyendocrinopathies, Autoimmune | 0.000271442 | 1 | 0 | BeFree |
| Neurologic Symptoms | 0.000271442 | 1 | 0 | BeFree |
| Papillary thyroid carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Sarcoma | 0.000271442 | 1 | 0 | BeFree |
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