CCL13(chemokine (C-C motif) ligand 13) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

17q11.2
基因染色体位置图

基因简述

基因简述

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. [provided by RefSeq, Sep 2014]

[中文简述(自动翻译):]  此抗微生物基因是聚集在染色体的q臂17细胞因子是参与免疫调节和炎症过程的分泌蛋白的一个家族几个半胱氨酸 - 半胱氨酸（CC）的细胞因子基因之一。在CC细胞因子是蛋白质特征在于两个相邻的半胱氨酸。由该基因编码的细胞因子显示单核细胞，淋巴细胞，嗜碱性粒细胞和嗜酸性粒细胞，但不是嗜中性粒细胞趋化活性。该趋化因子在炎症期间起着白细胞积累的作用。它也可能涉及在单核细胞进入血管壁的动脉粥样硬化过程中招聘。 [由RefSeq的，2014年9月提供]

OMIM数据库中对CCL13基因的介绍     Wikipedia数据库中对CCL13基因的介绍

基因序列

基因序列

CCL13基因的碱基序列：[NCBI]

基因突变

基因突变

CCL13基因的碱基突变：           显示全部snp
rs159313       rs159314       rs1431991       rs2072069       rs2072070       rs3136674       rs3136675       rs3136676       rs3136677       rs11575023       rs34566308       rs35880803       rs72827014       rs72827015       rs72827017       rs73288078       rs73988388       rs75348820       rs75960180       rs78188167       rs78322034       rs79547075       rs111740379       rs112523230       rs112908815       rs113131786       rs114311070       rs114853705       rs115292207       rs117860454       rs137918947       rs138618491       rs138879653       rs139142355       rs139839989       rs140451239       rs141616003      
rs142394840       rs142690955       rs143395542       rs143510106       rs143812279       rs144148427       rs145325564       rs145930174       rs145971766       rs146239444       rs146257516       rs146837190       rs147699636       rs148489898       rs148683606       rs149019155       rs149285419       rs149493844       rs149499630       rs151258837       rs181341478       rs181888648       rs182325517       rs182653739       rs183253878       rs183530014       rs183953161       rs184869697       rs185659231       rs185666006       rs186139146       rs187163309       rs187454526       rs188220432       rs188586958       rs189974231       rs190066432       rs190240720       rs191543093       rs191714413       rs191798516       rs192522491       rs192958655       rs199568961       rs199632606       rs200500996       rs201259871       rs201886392       rs367613739       rs367957184       rs369147614       rs370226389       rs370593553       rs371169143       rs371996404       rs372653174       rs373567305       rs374420615       rs375617099       rs375821836       rs376775055       rs376966664       rs377174787       rs377265823       rs377492922       rs377585122       rs397805813       rs527885671       rs527989203       rs528217716       rs528475517       rs529361931       rs529593644       rs530946379       rs531512532       rs532061187       rs532130217       rs532498797       rs533284969       rs533286145       rs533948385       rs534280819       rs534322751       rs534660128       rs535679541       rs537319630       rs537724219       rs538395736       rs538480893       rs538813803       rs539340794       rs539492618       rs539777336       rs540100018       rs540223474       rs540305919       rs541896903       rs542740740       rs543207368       rs543702050       rs544693952       rs545055622       rs546248321       rs547367773       rs547862202       rs548027302       rs549202577       rs549331512       rs549851903       rs549888747       rs550036442       rs550247990       rs551082483       rs552826608       rs553186952       rs554063990       rs554153805       rs554439623       rs555134592       rs555470907       rs556152249       rs560030786       rs560071676       rs560145924       rs561249042       rs563401756       rs563579431       rs564498523       rs564838885       rs564873957       rs565112305       rs565254387       rs568267286       rs568311080       rs569457861       rs569616499       rs569860985       rs570540135       rs570808516       rs570906925       rs571161215       rs573028578       rs573325873       rs573925061       rs575182510       rs576844037       rs577156523       rs577924843       rs745658417       rs745872598       rs746851613       rs748780538       rs749298428       rs749453524       rs749572938       rs750754428       rs751009010       rs751463485       rs751824838       rs752642615       rs753027787       rs753641013       rs754382301       rs754905287       rs755099124       rs755154135       rs755783195       rs755965057       rs756174315       rs756986624       rs757885510       rs757912599       rs759605331       rs759975138       rs761472042       rs762063628       rs762083323       rs762580055       rs762633152       rs762960516       rs763086648       rs763820628       rs764140711       rs766223344       rs766848594       rs768350035       rs768879474       rs769864937       rs771349142       rs771707528       rs772925066       rs773586979       rs773864741       rs774097182       rs774589882       rs775069930       rs775266633       rs775907825       rs776426842       rs776678465       rs776910644       rs777108695       rs777206868       rs777345964       rs777885624       rs778740838       rs778969931       rs779852870       rs780053174       rs780192818       rs780979455      

基因表达

基因表达

CCL13基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TGCTGCTTCACATTTAGCAG
59
TTTGGTTCTGAAGCTGCTG
59
TGCTGCTTCACATTTAGCA
58
TTTGGTTCTGAAGCTGCTG
59
AAGATCTCCTTGCAGAGGC
60
TTTGGTTCTGAAGATGACAGC
59
TGCTGCTTCACATTTAGCA
58
GTTTGGTTCTGAAGCTGCT
59
TAAGAAGATCTCCTTGCAGAG
57
GTTCTGAAGATGACAGCCT
57
CAGAAGGCTGTCATCTTCAG
58
CATATAATTCTGGACCCACTTCTC
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

CCL13基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CCL13基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005576
J3QLQ9(UniProtKB)
IEA
GO:0006955
J3QLQ9(UniProtKB)
IEA
GO:0008009
J3QLQ9(UniProtKB)
IEA
GO:0060326
J3QLQ9(UniProtKB)
IEA
GO:0002548
Q99616(UniProtKB)
IBA
GO:0005102
Q99616(UniProtKB)
TAS
GO:0005102
Q99616(UniProtKB)
TAS
GO:0005615
Q99616(UniProtKB)
IEA
GO:0005623
Q99616(UniProtKB)
IEA
GO:0006874
Q99616(UniProtKB)
TAS
GO:0006935
Q99616(UniProtKB)
TAS
GO:0006954
Q99616(UniProtKB)
IEA
GO:0007010
Q99616(UniProtKB)
IDA
GO:0007165
Q99616(UniProtKB)
TAS
GO:0007165
Q99616(UniProtKB)
TAS
GO:0007186
Q99616(UniProtKB)
IBA
GO:0007267
Q99616(UniProtKB)
TAS
GO:0008009
Q99616(UniProtKB)
IDA
GO:0008360
Q99616(UniProtKB)
IDA
GO:0030593
Q99616(UniProtKB)
IBA
GO:0043547
Q99616(UniProtKB)
IBA
GO:0048020
Q99616(UniProtKB)
IBA
GO:0048245
Q99616(UniProtKB)
IDA
GO:0048247
Q99616(UniProtKB)
IBA
GO:0050729
Q99616(UniProtKB)
IBA
GO:0070098
Q99616(UniProtKB)
IBA
GO:0070374
Q99616(UniProtKB)
IBA
GO:0071346
Q99616(UniProtKB)
IBA
GO:0071347
Q99616(UniProtKB)
IBA
GO:0071356
Q99616(UniProtKB)
IBA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控CCL13基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Macular Degeneration, Age-Related, 2 0.08 0 0 MGD
Asthma 0.003724241 6 0 BeFree_GAD
Dermatitis, Atopic 0.003267234 2 0 BeFree_LHGDN
Nasal Polyps 0.002995792 2 0 BeFree_LHGDN
Nephrosis 0.002995792 1 0 BeFree_LHGDN
Inflammation 0.00272435 1 0 LHGDN
Bronchiolitis, Viral 0.002367032 1 0 GAD
HIV Infections 0.002367032 1 0 GAD
Multiple Sclerosis 0.002367032 1 0 GAD
Respiratory Syncytial Virus Infections 0.002367032 1 0 GAD
Malignant neoplasm of ovary 0.002367032 1 0 GAD
Rheumatoid Arthritis 0.000814326 3 0 BeFree
Eczema 0.000542884 2 0 BeFree
Eosinophilia 0.000542884 2 0 BeFree
Eosinophilic disorder 0.000542884 2 0 BeFree
Disorder characterized by eosinophilia 0.000542884 2 0 BeFree
Glomerulonephritis 0.000271442 1 0 BeFree
Chronic Lymphocytic Leukemia 0.000271442 1 0 BeFree
Leukemia, Myelocytic, Acute 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Degenerative polyarthritis 0.000271442 1 0 BeFree
Pneumonia 0.000271442 1 0 BeFree
Diffuse Large B-Cell Lymphoma 0.000271442 1 0 BeFree
Allergic asthma 0.000271442 1 0 BeFree
Overweight 0.000271442 1 0 BeFree
Neurodegenerative Disorders 0.000271442 1 0 BeFree
Small Lymphocytic Lymphoma 0.000271442 1 0 BeFree
Nasopharyngeal carcinoma 0.000271442 1 0 BeFree

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