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The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.[provided by RefSeq, Nov 2008]
[中文简述(自动翻译):]  该基因的产物属于丝氨酸/苏氨酸蛋白激酶家族和对钙(2 +)/钙调蛋白依赖性蛋白激酶亚家族。钙信号是用于在谷氨酸突触可塑性的几个方面是至关重要的。在哺乳动物细胞中,所述酶是由四个不同的链:α,β,γ,和delta。这个基因的产物是一个增量链。在多个转录剪接变异体结果不同编码的亚型。这条产业链的不同亚型有不同的表达模式。[由RefSeq的,2008年11月提供]
CAMK2D基因(以及对应的蛋白质)的细胞分布位置:
CAMK2D基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Non-Small Cell Lung Carcinoma | 0.120271442 | 1 | 1 | BeFree_GWASCAT |
| Chronic Lymphocytic Leukemia | 0.12 | 1 | 1 | GWASCAT |
| Polycystic Ovary Syndrome | 0.12 | 1 | 0 | CTD_human |
| Myocardial Ischemia | 0.12 | 1 | 0 | CTD_human |
| Seizures | 0.08 | 1 | 0 | RGD |
| Cardiomegaly | 0.00272435 | 1 | 0 | LHGDN |
| Heart failure | 0.00272435 | 1 | 0 | LHGDN |
| Alcoholic Intoxication, Chronic | 0.002367032 | 1 | 0 | GAD |
| Mucocutaneous Lymph Node Syndrome | 0.002367032 | 1 | 0 | GAD |
| Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
| Epilepsy | 0.000271442 | 1 | 0 | BeFree |
| Epithelial ovarian cancer | 0.000271442 | 1 | 0 | BeFree |
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