C1QA基因详情-基因数据库-基因云馆

C1QA(complement component 1, q subcomponent, A chain) 转至新版数据库

基因简称(symbol)

C1QA [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

基因家族代码(gene_family_id)

492 [HGNC] [GenScript]

omim代码

120550

entrez码

712 [Vega]

vega基因码

OTTHUMG00000002893

ensembl基因码

ENSG00000173372 [Ensembl]

基因家族(gene family)

Complement system

refseq数据库代号

NM_015991

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

01p36.3-p34.1

同源基因名称(alias name)

基因名称批准使用时间(date_approved_reserved)

2001-06-22T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

2006-02-09T00:00:00Z

更新时间(date_modified)

2015-04-22T00:00:00Z

ucsc码

uc001bfy.3

ena

AF135157

ccds数据码

CCDS226

uniprot数据码

P02745

pubmed代码

1537612

mgd码

MGI:88223

rgd码

RGD:1306716

生命科学数据库(lsdb)

C1QAbase: Mutation registry for C1qA deficiency|http://rna.uta.fi/C1QAbase/index2.html|LRG_22|http://www.lrg-sequence.org/LRG/LRG_22

更新时间(date modified)

2015-04-22T00:00:00Z

cosmic

C1QA

mirbase

基因曾用简称(prev symbol)

基因曾用名称(prev name)

complement component 1, q subcomponent, alpha polypeptide

homeodb

cosmic

C1QA

snornabase

bioparadigms slc

orphanet

221162

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

1p36.3-p34.1

This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):] 该基因编码的人补体C1q子组件的主要成分。与C1R和C1s的C1q的联营以得到血清补体系统的第一组分。 C1q的缺失一直与红斑狼疮和肾小球肾炎相关。 C1q的由18多肽链：六个链，6个B链，以及6架C-链。每条链包含位于N末端和C末端的球状区域附近的胶原样区。在A，B，和C-链1号染色体上排列顺序A-C-B该基因编码的人补体C1q子的A链多肽。 [由RefSeq的，2008年7月提供]

OMIM数据库中对C1QA基因的介绍 Wikipedia数据库中对C1QA基因的介绍

C1QA基因的碱基序列：[NCBI]

C1QA基因的碱基突变：显示全部snp

rs172378 rs292001 rs292002 rs649114 rs649538 rs651520 rs651534 rs680123 rs1044378 rs1044379 rs2935539 rs2935540 rs2935541 rs2935542 rs2986658 rs6667835 rs6682948 rs6691239 rs10917274 rs12033074 rs12058824 rs12060266 rs12740591 rs17879174 rs17879206 rs17880338 rs17880529 rs17880570 rs17880932 rs17881187 rs17881257 rs17881578 rs17881812 rs17883003 rs17883291 rs17883510 rs17883533

rs17884308 rs17884542 rs17884678 rs17886786 rs17887074 rs17887096 rs35138344 rs35328734 rs41302011 rs41507347 rs45475393 rs45542936 rs45547138 rs45557836 rs45571831 rs56219139 rs57535094 rs58701628 rs58745956 rs59028738 rs60865112 rs72877137 rs75137403 rs75176013 rs75353031 rs77839237 rs111676235 rs112251360 rs113295373 rs121909581 rs138337227 rs138830154 rs139249275 rs139427610 rs139659355 rs140680028 rs141400442 rs141848434 rs141997172 rs143863208 rs143921949 rs144937808 rs145158391 rs146305358 rs146884691 rs147435427 rs147811463 rs148094496 rs149050968 rs149230484 rs149969645 rs150492858 rs150607590 rs150942939 rs151131264 rs180679721 rs184406897 rs184961232 rs186882120 rs187711231 rs189694611 rs191371712 rs192256756 rs199788933 rs200333256 rs200812579 rs201074672 rs201517118 rs201693493 rs201816009 rs201975189 rs367594784 rs367674617 rs368075767 rs368211237 rs368473383 rs369062665 rs369926227 rs372360743 rs372914310 rs375714569 rs375992274 rs376010024 rs376479366 rs376612598 rs377231186 rs377376778 rs527917138 rs528301944 rs528617015 rs530440701 rs532590685 rs532807005 rs533261717 rs535382261 rs537283100 rs537283570 rs537473350 rs537944838 rs538136560 rs539670341 rs539755759 rs540004801 rs541112662 rs541629893 rs542352697 rs542889390 rs543093863 rs543136291 rs544248455 rs544956164 rs545951878 rs546090165 rs547523108 rs548454160 rs548787412 rs548929041 rs549123137 rs549443550 rs549891695 rs551226253 rs551625393 rs551741070 rs551896337 rs553702124 rs553960525 rs554406495 rs555696737 rs556144666 rs556221323 rs556810599 rs556911649 rs557627584 rs558083177 rs558146328 rs559395274 rs560307757 rs560443348 rs560644440 rs560874109 rs561518701 rs561847201 rs563149417 rs564519303 rs565285688 rs565719232 rs566079361 rs566727012 rs567106778 rs568891417 rs569738031 rs569879913 rs569999510 rs570295219 rs571792988 rs571793396 rs572151019 rs572316833 rs572428849 rs572484613 rs572822370 rs573766771 rs574588341 rs575152869 rs577146223 rs577228537 rs745489495 rs745706454 rs746008058 rs746607173 rs747014212 rs747233021 rs747258468 rs747729685 rs748236589 rs748582147 rs748583157 rs748632438 rs748648261 rs748785129 rs749595647 rs750646958 rs750747894 rs751087244 rs751668628 rs751720642 rs752735594 rs753354060 rs753525833 rs753671365 rs754597784 rs755011795 rs755524842 rs755725663 rs755854700 rs757112554 rs757156581 rs757548258 rs757566387 rs757675781 rs758287396 rs758533012 rs758587918 rs758718727 rs758788716 rs759104463 rs759710656 rs759712266 rs759914877 rs760737669 rs760792758 rs760998313 rs761269725 rs761744728 rs761882792 rs762246766 rs762772392 rs763463327 rs763585444 rs763783488 rs763842392 rs764123120 rs764642093 rs765090332 rs765609011 rs765715625 rs766456234 rs766694409 rs766824374 rs766993678 rs767339831 rs767465436 rs767510705 rs768311730 rs769007084 rs769041272 rs769802299 rs769861384 rs769898707 rs770130739 rs770424644 rs770590046 rs770609711 rs770863244 rs771758729 rs771831280 rs772262008 rs772544683 rs772710133 rs773281752 rs773635803 rs773758868 rs773937428 rs774038943 rs774041017 rs774674695 rs774871521 rs775077199 rs775331515 rs775675979 rs776133244 rs776416316 rs776583731 rs776729628 rs777457473 rs778184440 rs778763686 rs779154811 rs779210041 rs779568085 rs779801061 rs779842833 rs779897709 rs780252137 rs781431506 rs781475229 rs781752563

C1QA基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

CTCTATGGTGACCGAGGAC

59

TTTAAGGCCTTGGATGCCT

59

GGGAGGGAAATAACTGTGC

58

CATGATGCCTCCATTCTGG

58

CTCTATGGTGACCGAGGAC

59

CCTTTAAGGCCTTGGATGC

59

CAGAATGGAGGCATCATGG

58

GTCCTCGGTCACCATAGAG

59

AGGGAGGGAAATAACTGTGC

60

ATGATGCCTCCATTCTGGG

60

CTCTATGGTGACCGAGGAC

59

CTTTAAGGCCTTGGATGCC

59

CTCTATGGTGACCGAGGAC

59

CCTTTAAGGCCTTGGATGC

59

CTCTATGGTGACCGAGGAC

59

CTTTAAGGCCTTGGATGCC

59

CTCTATGGTGACCGAGGAC

59

TTTAAGGCCTTGGATGCCT

59

尚未收录相关数据

C1QA基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

C1QA基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0004252

P02745(UniProtKB)

TAS

GO:0004252

P02745(UniProtKB)

TAS

GO:0005515

P02745(UniProtKB)

IPI

GO:0005515

P02745(UniProtKB)

IPI

GO:0005515

P02745(UniProtKB)

IPI

GO:0005576

P02745(UniProtKB)

TAS

GO:0005576

P02745(UniProtKB)

TAS

GO:0005576

P02745(UniProtKB)

TAS

GO:0005576

P02745(UniProtKB)

TAS

GO:0005581

P02745(UniProtKB)

IEA

GO:0005602

P02745(UniProtKB)

TAS

GO:0006508

P02745(UniProtKB)

IEA

GO:0006956

P02745(UniProtKB)

TAS

GO:0006958

P02745(UniProtKB)

TAS

GO:0007267

P02745(UniProtKB)

TAS

GO:0010039

P02745(UniProtKB)

IEA

GO:0045087

P02745(UniProtKB)

IEA

GO:0070062

P02745(UniProtKB)

IDA

GO:0005576

X6RLJ0(UniProtKB)

IEA

GO:0005581

X6RLJ0(UniProtKB)

IEA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控C1QA基因的相关microRNA：

hsa-miR-335

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Lupus Erythematosus, Systemic	0.211368221	9	0	BeFree_CTD_human_GAD_MGD
Exanthema	0.12	1	0	CTD_human
IGA Glomerulonephritis	0.12	2	0	CTD_human
Glomerulonephritis, Membranoproliferative	0.12	1	0	CTD_human
Immune Complex Diseases	0.12	1	0	CTD_human
C1q DEFICIENCY	0.12	0	1	CLINVAR
Iron deficiency anemia	0.08	1	0	RGD
Malignant neoplasm of breast	0.00554839	3	0	BeFree_GAD
Lymphoma, Follicular	0.005362824	1	0	BeFree_GAD_LHGDN
Lupus Erythematosus	0.003724241	5	0	BeFree_GAD
Neoplasm Metastasis	0.003267234	2	1	BeFree_LHGDN
Diffuse Large B-Cell Lymphoma	0.002909916	3	1	BeFree_GAD
Lupus Erythematosus, Cutaneous	0.00272435	1	0	LHGDN
Mammary Neoplasms	0.00272435	1	0	LHGDN
Lupus Nephritis	0.002367032	1	0	GAD
B-Cell Lymphomas	0.002367032	1	0	GAD
Amyloid Neuropathies, Familial	0.002367032	1	0	GAD
Lupus Vulgaris	0.001357209	5	0	BeFree
Lupus Erythematosus, Discoid	0.001357209	5	0	BeFree
Breast Carcinoma	0.000814326	3	0	BeFree
Glaucoma	0.000271442	1	0	BeFree
Nephritis	0.000271442	1	0	BeFree
PHOTOPAROXYSMAL RESPONSE 1	0.000271442	1	0	BeFree