ALDH2(aldehyde dehydrogenase 2 family (mitochondrial))

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库
12q24.12

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2011]

[中文简述(自动翻译):]  这种蛋白质属于醛脱氢酶家族的蛋白质。醛脱氢酶是醇代谢的主要氧化途径的第二个酶。醛脱氢酶,胞质和线粒体的两个主要的肝同种型,可以通过它们的电泳迁移率,动力学性质,和亚细胞定位进行区分。最白种人有两个主要的同功酶,而东方人的约50%具有胞质同工酶但不是线粒体同工酶。东方人比白种人之间的急性酒精中毒的一个显着更高的频率可能与缺乏线粒体同工酶的催化活性的形式。曝光增加到乙醛个体与无催化活性的形式也可以赋予更大的易感性许多类型的癌症。这个基因编码的线粒体同种型,其具有低的公里为乙醛,和在线粒体基质被定位。在多个转录剪接变异体导致不同的编码亚型。[由RefSeq的,2011年3月提供]

ALDH2基因的碱基序列:[NCBI]
ALDH2基因的碱基突变:           显示全部snp
rs440       rs441       rs671       rs886205       rs968529       rs1062136       rs1064933       rs2106696       rs2158028       rs2158029       rs2238151       rs2238152       rs2283354       rs3832868       rs4646776       rs4646777       rs4646778       rs4646779       rs4646780       rs4646782       rs4648328       rs4767035       rs4767939       rs4767944       rs7136890       rs7296651       rs7311852       rs7312055       rs7397469       rs7397491       rs7970477       rs10450717       rs10744777       rs10774637       rs10774638       rs10849970       rs11066022      
rs11066024       rs11066026       rs11066027       rs11066028       rs11066029       rs11304348       rs11609628       rs11613231       rs11613713       rs11614684       rs11834780       rs12099590       rs12312867       rs12830829       rs13306163       rs13306164       rs13306165       rs13306166       rs16941667       rs16941669       rs34083959       rs35154896       rs35239056       rs35650885       rs55737128       rs56059146       rs56077984       rs56884502       rs57046733       rs58280059       rs58352818       rs59300843       rs59370732       rs60039171       rs60351551       rs60826763       rs61941276       rs61941278       rs71445557       rs71445558       rs71465815       rs73205605       rs73205606       rs73420482       rs73420483       rs73420485       rs73420492       rs74318806       rs74429409       rs74595229       rs74849450       rs74912896       rs74938832       rs75029020       rs75076596       rs75162023       rs75200242       rs75262684       rs75282498       rs75285123       rs75288289       rs75480510       rs75584029       rs75809969       rs75812027       rs75822349       rs75852434       rs75879223       rs75898575       rs76081702       rs76126169       rs76211736       rs76326141       rs76439630       rs76449681       rs76705441       rs76924519       rs76977743       rs77039719       rs77148608       rs77215568       rs77251453       rs77384237       rs77422707       rs77603030       rs77664467       rs77819145       rs77855595       rs77980765       rs78274783       rs78275173       rs78439634       rs78560131       rs78602437       rs78617366       rs78693422       rs78783055       rs78809435       rs78843040       rs78991894       rs79007373       rs79073142       rs79100299       rs79159682       rs79323183       rs79463616       rs79481577       rs79596048       rs79682625       rs79950423       rs79961638       rs80142727       rs80168235       rs80264018       rs111281658       rs111309293       rs111324903       rs111518501       rs111540844       rs111540940       rs111627571       rs111689914       rs111756501       rs111758017       rs111961937       rs111994080       rs112000082       rs112003583       rs112019550       rs112048865       rs112169152       rs112196758       rs112230847       rs112239060       rs112321591       rs112409341       rs112460655       rs112494677       rs112609680       rs112698588       rs112813318       rs112888725       rs112909894       rs112924001       rs112940500       rs112980762       rs113025960       rs113056077       rs113098118       rs113144828       rs113349021       rs113387298       rs113539902       rs113554658       rs113635624       rs113648146       rs113648300       rs113648753       rs113720691       rs113773160       rs113787291       rs113888278       rs114352406       rs114588087       rs114800119       rs114882964       rs115341729       rs115350402       rs115840215       rs116026068       rs116090873       rs116212158       rs116213591       rs116422312       rs116448397       rs116758112       rs116818840       rs117358900       rs117738948       rs137865762       rs137958788       rs138012599       rs138201631       rs138202608       rs138316993       rs138324767       rs138392178       rs138443541       rs138505396       rs138639429       rs138843737       rs138903429       rs138903598       rs138931620       rs139111005       rs139133423       rs139552439       rs139702147       rs139710275       rs139862632       rs139911899       rs139968732       rs140036785       rs140064497       rs140143970       rs140347209       rs140392982       rs140459222       rs140710597       rs140871592       rs140912235       rs140919090       rs140984356       rs141025702       rs141061085       rs141288612       rs141332736       rs141373324       rs141407267       rs141555810       rs141556759       rs141574314       rs141696414       rs141937558       rs141985715       rs142050144       rs142271678       rs142293232       rs142331753       rs142399818       rs142437288       rs142509481       rs142548710       rs142646023       rs142881599       rs142915302       rs143259494       rs143337602       rs143437295       rs143578304       rs143671643       rs143733804       rs143866724       rs144033055       rs144127636       rs144161093       rs144260138       rs144263287       rs144300145       rs144328002       rs144375294       rs144462687       rs144477040       rs144598865       rs144641798       rs144739856       rs145070720       rs145077856       rs145146138       rs145195569       rs145216963       rs145528471       rs145535938       rs145567970       rs145723360       rs145790749       rs146063905       rs146167264       rs146185317       rs146204588       rs146223306       rs146304025       rs146323899       rs146354947       rs146468087       rs146486622       rs146507248       rs146607632       rs146739827       rs146891659       rs146945498       rs147035515       rs147049749       rs147086207       rs147123809       rs147178045       rs147195398       rs147301555       rs147529779       rs147568589       rs147584072       rs147883120       rs147887880       rs147915948       rs148039593       rs148145145       rs148215148       rs148340076       rs148410674       rs148448691       rs148568389       rs148600666       rs148620777       rs148698157       rs148742173       rs148794760       rs148853596       rs148905314       rs149093906       rs149130655       rs149145363       rs149241562       rs149377733       rs149442966       rs149627028       rs149677480       rs149729415       rs149766078       rs149824295       rs149911401       rs149961069       rs149999328       rs150107349       rs150202179       rs150253385       rs150347478       rs150432702       rs150543601       rs150595730       rs150631941       rs150789517       rs151016544       rs151075060       rs151127608       rs151143780       rs180730623       rs180743898       rs180776929       rs180898905       rs180908341       rs181199019       rs181265686       rs181369161       rs181557494       rs181565285       rs181568947       rs181649797       rs181828965       rs181832061       rs182021595       rs182230592       rs182234983       rs182362882       rs182512771       rs182625224       rs182911882       rs182953171       rs183058499       rs183090649       rs183108437       rs183223873       rs183356166       rs183385655       rs183529440       rs183735691       rs183864989       rs183870967       rs183882694       rs183974819       rs184011159       rs184047998       rs184112252       rs184117460       rs184158075       rs184287363       rs184399194       rs184403232       rs184413574       rs184571718       rs184688239       rs185022735       rs185039901       rs185042017       rs185052213       rs185376538       rs185494407       rs185712552       rs185872513       rs185890332       rs185995403       rs185999936       rs186045084       rs186089024       rs186190096       rs186367832       rs186370722       rs186439725       rs186454360       rs186749217       rs186845730       rs186880682       rs186903686       rs187025036       rs187059348       rs187061717       rs187334097       rs187335908       rs187572349       rs187740161       rs187839566       rs187906572       rs187939137       rs188010264       rs188140327       rs188243734       rs188250257       rs188309549       rs188385150       rs188794219       rs188946187       rs189047978       rs189050296       rs189076339       rs189155283       rs189286053       rs189374324       rs189388331       rs189440027       rs189528812       rs189543272       rs189598323       rs189647488       rs189723413       rs189880277       rs189918347       rs189985085       rs190110704       rs190129288       rs190234774       rs190334502       rs190383046       rs190454593       rs190454889       rs190463190       rs190633288       rs190672480       rs190764869       rs190808326       rs190865348       rs190914158       rs190947876       rs191158181       rs191240032       rs191252491       rs191277979       rs191300307       rs191496215       rs191578499       rs191593687       rs191673261       rs191935085       rs192282635       rs192312933       rs192386824       rs192517874       rs192580138       rs192629795       rs192813232       rs192883344       rs192979892       rs193056481       rs193200096       rs199568597       rs199624420       rs199724286       rs199811756       rs199847950       rs199967065       rs199997803       rs200164179       rs200346565       rs200369180       rs200408280       rs200738174       rs200757003       rs200975817       rs201023185       rs201108880       rs201189881       rs201257394       rs201405479       rs201582342       rs201705553       rs201725825       rs201745983       rs201835306       rs201939387       rs202215192       rs202226446       rs367691794       rs367711233       rs367911769       rs368167122       rs368288474       rs368356402       rs368364470       rs368395266       rs368435076       rs368665921       rs368780783       rs368798841       rs369166762       rs369579839       rs369662183       rs369765587       rs369822900       rs369885651       rs369974228       rs370071768       rs370128272       rs370850207       rs370855783       rs371068716       rs371108126       rs371173086       rs371202367       rs371332731       rs371493214       rs371600547       rs371851241       rs371993659       rs372053825       rs372327619       rs372735393       rs372769067       rs372806989       rs372844815       rs372921830       rs372948453       rs373059460       rs373094911       rs373123763       rs373312771       rs373644927       rs373787552       rs374137756       rs374377652       rs374472479       rs374527730       rs374555554       rs374576238       rs374686453       rs374700020       rs374801567       rs374813139       rs375070937       rs375313806       rs375512816       rs375522582       rs375708006       rs375845001       rs376029750       rs376099569       rs376294289       rs376595585       rs376601246       rs376773752       rs376999045       rs377009438       rs377123780       rs377171183       rs377343804       rs377453615       rs377514734       rs377703701       rs397807093       rs398021083       rs527295411       rs527371980       rs527533208       rs527603470       rs527642321       rs527729101       rs527735302       rs527802218       rs527876023       rs527883262       rs527914959       rs527974577       rs527986045       rs528053256       rs528141849       rs528211578       rs528245693       rs528270809       rs528574047       rs528840398       rs529005365       rs529046528       rs529048246       rs529193148       rs529298444       rs529336405       rs529412211       rs529421549       rs529482742       rs529520609       rs529597379       rs529691860       rs529768244       rs529770662       rs529824281       rs530004333       rs530010258       rs530116928       rs530121018       rs530166721       rs530273658       rs530275509       rs530348512       rs530442805       rs530488256       rs530508782       rs530550398       rs530632664       rs530776882       rs530839095       rs531090732       rs531124028       rs531172803       rs531249743       rs531359250       rs531557713       rs531776861       rs531780043       rs531780523       rs531817616       rs531877315       rs532120807       rs532162181       rs532182171       rs532325950       rs532379448       rs532452486       rs532455586       rs532463245       rs532505949       rs532579933       rs532689617       rs532701208       rs532777142       rs532831948       rs532908065       rs532985612       rs533001896       rs533061615       rs533267797       rs533354114       rs533391678       rs533526749       rs533528545       rs533611625       rs533647801       rs533701580       rs534127667       rs534144169       rs534219040       rs534231552       rs534435914       rs534531260       rs534551787       rs534558763       rs534621858       rs534660080       rs534691599       rs534703777       rs534740237       rs534815980       rs534925026       rs534989398       rs535214463       rs535319998       rs535354113       rs535393932       rs535472347       rs535512021       rs535558280       rs535676226       rs535918955       rs535950825       rs536141708       rs536195128       rs536225007       rs536238974       rs536279436       rs536321330       rs536496325       rs536532796       rs536553868       rs536593145       rs536634765       rs536743697       rs536895009       rs537014187       rs537025752       rs537046626       rs537105929       rs537146650       rs537204951       rs537213711       rs537219682       rs537366295       rs537374639       rs537387970       rs537426333       rs537502637       rs537564002       rs537597971       rs537600420       rs538042841       rs538087133       rs538111819       rs538193475       rs538246934       rs538327449       rs538360704       rs538364218       rs538464024       rs538622061       rs538638137       rs538781336       rs538812438       rs538970340       rs539125173       rs539175645       rs539199200       rs539266485       rs539281413       rs539313357       rs539610741       rs539648317       rs539896430       rs539961470       rs539982429       rs540045227       rs540066570       rs540073928       rs540100648       rs540181549       rs540182020       rs540537301       rs540582027       rs540863474       rs540905375       rs540929444       rs540930974       rs541022356       rs541097684       rs541130823       rs541136552       rs541144061       rs541259696       rs541340649       rs541471054       rs541595136       rs541753563       rs541764512       rs541810028       rs541846943       rs541860485       rs541922147       rs541956023       rs541964823       rs542150554       rs542206089       rs542242422       rs542271818       rs542281516       rs542385946       rs542418016       rs542493407       rs542620029       rs542666146       rs542684310       rs542753887       rs542824983       rs542827797       rs542869202       rs543005363       rs543030829       rs543044407       rs543116783       rs543409735       rs543485437       rs543508285       rs543519552       rs543521596       rs543527126       rs543619277       rs543721548       rs543854266       rs543884211       rs543943873       rs544016456       rs544122221       rs544247104       rs544482704       rs544604410       rs544607302       rs544714733       rs544785642       rs544812001       rs545004870       rs545021129       rs545043931       rs545216000       rs545246348       rs545467917       rs545608264       rs545671616       rs545704006       rs545750197       rs545782211       rs545801429       rs545849122       rs545930817       rs546100034       rs546224185       rs546377340       rs546519114       rs546531903       rs546599236       rs546630801       rs546693939       rs546869356       rs547033571       rs547105889       rs547206978       rs547207199       rs547273897       rs547347016       rs547384727       rs547409546       rs547473897       rs547563827       rs547567831       rs547680245       rs547685237       rs547821012       rs548170190       rs548244972       rs548292659       rs548293892       rs548467141       rs548470493       rs548504368       rs548540847       rs548570403       rs548639255       rs548702415       rs548816134       rs548852503       rs548904490       rs548909563       rs548953144       rs548961554       rs549293774       rs549293883       rs549324820       rs549379651       rs549492012       rs549576911       rs549597927       rs549645190       rs549780715       rs549940231       rs549944912       rs549949844       rs550022818       rs550093885       rs550110645       rs550193631       rs550221993       rs550255304       rs550256437       rs550423407       rs550527886       rs550574201       rs550693989       rs550737318       rs550809455       rs550978665       rs551005789       rs551015634       rs551031403       rs551054294       rs551088152       rs551145910       rs551263044       rs551299805       rs551307398       rs551345492       rs551356304       rs551677117       rs551783677       rs551809595       rs551818282       rs551857413       rs551951774       rs551971262       rs552089657       rs552184946       rs552272048       rs552308357       rs552386216       rs552485690       rs552490484       rs552607188       rs552670029       rs552684652       rs552810516       rs552841342       rs552961908       rs552982850       rs553021552       rs553060638       rs553069648       rs553146645       rs553215937       rs553221028       rs553222159       rs553345524       rs553384830       rs553533792       rs553567477       rs553584422       rs553606146       rs553689404       rs553701288       rs553826815       rs553975153       rs554159517       rs554283715       rs554304287       rs554490237       rs554548151       rs554568102       rs554638363       rs554677086       rs554905215       rs554909623       rs554937672       rs554938866       rs554944381       rs555019657       rs555192404       rs555198441       rs555501971       rs555529565       rs555628998       rs555776107       rs555872966       rs555936151       rs555940803       rs555941941       rs556048130       rs556052909       rs556092673       rs556394428       rs556536983       rs556664873       rs556698206       rs556699179       rs556799020       rs556863608       rs556864953       rs556919518       rs557021359       rs557180557       rs557222968       rs557426856       rs557444546       rs557590013       rs557653692       rs557668569       rs557685262       rs557808902       rs557844319       rs557846133       rs557857182       rs557859017       rs558161025       rs558237738       rs558400921       rs558458730       rs558512612       rs558548685       rs558574307       rs558611574       rs558636382       rs558642537       rs558668011       rs558776633       rs558808303       rs558809393       rs558903368       rs558925875       rs559065478       rs559112110       rs559289355       rs559329220       rs559427809       rs559449509       rs559516464       rs559606386       rs559715053       rs559722923       rs559785262       rs559845408       rs559920979       rs560014745       rs560065926       rs560165119       rs560252444       rs560261267       rs560373324       rs560501488       rs560607912       rs560660376       rs560695779       rs560695839       rs560781954       rs560787949       rs561044476       rs561079679       rs561150904       rs561157475       rs561160219       rs561200623       rs561270201       rs561285636       rs561470280       rs561496548       rs561559080       rs561628593       rs561665847       rs561689045       rs561689487       rs561726454       rs561848862       rs561987414       rs562035672       rs562058340       rs562075000       rs562159483       rs562165815       rs562218802       rs562241287       rs562241348       rs562275567       rs562349449       rs562359900       rs562395822       rs562411249       rs562477936       rs562621848       rs562838090       rs562878337       rs562981409       rs563018559       rs563159136       rs563225494       rs563245560       rs563250001       rs563324047       rs563397478       rs563404007       rs563421472       rs563619486       rs563749411       rs563765107       rs563802560       rs563893378       rs563911739       rs563930940       rs563967924       rs564005438       rs564076617       rs564078391       rs564185867       rs564363661       rs564503248       rs564538700       rs564556413       rs564643567       rs564760822       rs564788939       rs564927508       rs565067318       rs565097426       rs565110485       rs565142575       rs565151615       rs565304289       rs565434620       rs565550809       rs565642382       rs565702788       rs565768886       rs565784749       rs565931073       rs565972402       rs566032412       rs566179917       rs566207615       rs566294630       rs566294647       rs566358087       rs566590864       rs566829453       rs566836140       rs566836634       rs566877088       rs566970096       rs566981949       rs567092638       rs567143183       rs567255002       rs567485403       rs567550749       rs567683546       rs567761047       rs567771820       rs567817871       rs567854769       rs567863645       rs568134360       rs568145006       rs568159938       rs568172477       rs568338025       rs568437854       rs568682226       rs568717898       rs568720832       rs568781254       rs568794405       rs568893252       rs568959222       rs569237698       rs569354452       rs569388000       rs569393965       rs569534440       rs569556661       rs569604442       rs569642618       rs569670985       rs569706887       rs569719481       rs569804761       rs569911583       rs569923445       rs570050935       rs570058859       rs570076673       rs570248732       rs570358948       rs570389870       rs570423713       rs570864593       rs570870186       rs571038168       rs571106658       rs571110548       rs571131053       rs571161985       rs571177410       rs571234717       rs571330917       rs571334921       rs571448047       rs571588910       rs571676855       rs571679923       rs571716822       rs571813420       rs572001362       rs572197063       rs572232925       rs572397206       rs572402172       rs572468460       rs572696320       rs572739972       rs572845152       rs572876274       rs572961614       rs572999738       rs573032973       rs573158338       rs573159424       rs573257814       rs573353590       rs573421256       rs573422952       rs573445090       rs573448138       rs573516739       rs573628945       rs573851913       rs573971810       rs574122141       rs574128418       rs574180703       rs574258669       rs574259526       rs574464772       rs574488059       rs574527758       rs574551187       rs574579312       rs574618021       rs574631228       rs574661718       rs574894372       rs575018878       rs575023096       rs575224313       rs575231682       rs575265959       rs575362769       rs575427890       rs575474080       rs575475254       rs575512196       rs575517249       rs575551594       rs575558603       rs575643836       rs575673322       rs575860861       rs575919683       rs575953094       rs575984412       rs575998739       rs576040981       rs576113952       rs576228549       rs576258256       rs576325361       rs576350725       rs576398974       rs576422402       rs576695884       rs576731008       rs576735859       rs576865880       rs576865946       rs577047371       rs577063216       rs577065128       rs577081910       rs577147234       rs577222113       rs577262190       rs577280770       rs577355302       rs577393321       rs577500152       rs577637684       rs577757624       rs577898083       rs577947906       rs578178328       rs745399368       rs745474640       rs745487886       rs745686688       rs745937439       rs745944562       rs746086528       rs746346111       rs746521872       rs746637446       rs746814335       rs746940858       rs747014064       rs747096195       rs747227657       rs747280625       rs747287850       rs747323948       rs747615625       rs747670612       rs747745469       rs747970101       rs748413982       rs748467000       rs748550381       rs748643347       rs748886318       rs748932783       rs748985887       rs749044025       rs749059028       rs749172696       rs749478901       rs749574153       rs749630753       rs749678731       rs749680221       rs749694206       rs749863724       rs749895638       rs749897694       rs749950720       rs750085443       rs750174020       rs750341773       rs750453063       rs750466695       rs750644484       rs750928778       rs751006312       rs751128369       rs751364520       rs751415641       rs751540537       rs751588480       rs751643804       rs751728275       rs751776846       rs751889386       rs751931265       rs751980357       rs752215510       rs752593972       rs752652573       rs752737734       rs752792758       rs752989672       rs753058436       rs753125040       rs753304028       rs753357413       rs753520756       rs753791195       rs753847903       rs753972907       rs753973836       rs754048687       rs754265114       rs754387972       rs754530560       rs754656921       rs754808238       rs754845817       rs755001438       rs755207315       rs755268259       rs755347814       rs755579750       rs755761896       rs756057023       rs756069092       rs756140607       rs756204939       rs756266195       rs756375309       rs756482078       rs756650696       rs756781003       rs756978401       rs757254188       rs757563141       rs757715270       rs757770420       rs757893333       rs757929413       rs757980778       rs758039402       rs758149074       rs758344748       rs758376495       rs758384827       rs758442315       rs758493011       rs758654733       rs758715136       rs758863490       rs758880637       rs758915089       rs758997044       rs759174174       rs759333754       rs759401887       rs759439114       rs759512257       rs759563266       rs759588558       rs759815398       rs759880249       rs759981145       rs760105168       rs760390936       rs760414925       rs760416164       rs760442360       rs760546011       rs760854542       rs760971491       rs761027124       rs761027843       rs761154464       rs761666386       rs761681824       rs761724588       rs761731217       rs761778133       rs761993467       rs762288460       rs762299805       rs762429882       rs762717506       rs762718195       rs762922297       rs762937320       rs763211754       rs763250692       rs763302651       rs763334012       rs763365886       rs763423158       rs763568016       rs763578676       rs763849334       rs763851306       rs763918388       rs764022056       rs764073001       rs764415326       rs764444201       rs764536284       rs764544132       rs764594848       rs764713289       rs764776351       rs764810743       rs764941692       rs765039944       rs765185646       rs765328106       rs765448984       rs765515172       rs765681003       rs765692515       rs765696142       rs765749495       rs765859442       rs765912648       rs765981127       rs766265612       rs766266356       rs766312843       rs766318505       rs766339559       rs766577822       rs766648464       rs766650595       rs766664074       rs766713154       rs766715363       rs766818746       rs766849182       rs767021356       rs767144087       rs767280255       rs767381323       rs767419163       rs767739457       rs767805753       rs767867409       rs768020372       rs768023125       rs768044419       rs768251860       rs768374581       rs768421998       rs768498998       rs768692057       rs768761406       rs769003115       rs769168320       rs769295295       rs769503071       rs769724893       rs769913072       rs770124797       rs770346038       rs770348553       rs770370161       rs770625268       rs770671499       rs770789545       rs770830521       rs770910524       rs771107075       rs771107373       rs771205908       rs771277872       rs771527950       rs771626523       rs771649244       rs771673604       rs771771961       rs771776201       rs771798331       rs771977554       rs772193708       rs772296175       rs772375885       rs772390903       rs772515139       rs772741185       rs772769308       rs772821114       rs773035280       rs773061911       rs773061919       rs773099733       rs773112716       rs773619166       rs773666853       rs773842458       rs774052763       rs774238705       rs774292279       rs774511894       rs774642632       rs774697819       rs774840012       rs775082307       rs775156542       rs775259939       rs775286182       rs775319485       rs775694148       rs775770152       rs775896862       rs775896971       rs775949935       rs776126532       rs776136452       rs776223807       rs776273476       rs776421832       rs776526118       rs776618281       rs776963882       rs777018900       rs777079274       rs777093529       rs777131735       rs777216699       rs777507942       rs777694079       rs777767582       rs777855957       rs777877167       rs777988122       rs778189721       rs778279256       rs778304509       rs778442341       rs778449798       rs778557236       rs778751819       rs778805131       rs778921284       rs778990792       rs779006912       rs779466419       rs779535686       rs779592656       rs779701360       rs779941847       rs780035440       rs780170831       rs780221725       rs780616608       rs780899853       rs781131621       rs781185157       rs781225098       rs781313528       rs781322365       rs781416731       rs781479853       rs781556042       rs869263253      

ALDH2基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GTCTTCACAAAGGATTTGGAC
58
ATCATAGCAGTTGACCCAC
57
TGGTTACTTCATCCAGCCC
59
CATAGCAGTTGACCCTCCT
59
ACAATGAATGGCACGATGC
60
TGTCCACATCTTCCTTGTCC
60
CCAAGAGCGTTTACGTGTG
60
TCCACATCTTCCTTGTCCC
59
CCAAGAGCGTTTACGTGTG
60
CTTGTCCACATCTTCCTTGTC
59
AGACACATTAATCTCCTTGCAC
59
GGCTTTACACCTGAGAGCT
59
ACAATGAATGGCACGATGC
60
TCCACATCTTCCTTGTCCC
59
GTGGTTACTTCATCCAGCC
58
ATAGCAGTTGACCCTCCTC
59
TCATTCCGTGGAATTTCCC
58
TCATCACAACCACGTTTCC
58
CCAAGAGCGTTTACGTGTG
60
TGTCCACATCTTCCTTGTCC
60
      尚未收录相关数据

ALDH2基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ALDH2基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0004029
P05091(UniProtKB)
EXP
GO:0004029
P05091(UniProtKB)
IDA
GO:0004029
P05091(UniProtKB)
EXP
GO:0004030
P05091(UniProtKB)
TAS
GO:0005759
P05091(UniProtKB)
TAS
GO:0005759
P05091(UniProtKB)
TAS
GO:0005975
P05091(UniProtKB)
TAS
GO:0006066
P05091(UniProtKB)
TAS
GO:0006068
P05091(UniProtKB)
IEA
GO:0006069
P05091(UniProtKB)
TAS
GO:0009055
P05091(UniProtKB)
TAS
GO:0070062
P05091(UniProtKB)
IDA
GO:0070062
P05091(UniProtKB)
IDA
GO:0016620
S4R3S4(UniProtKB)
IEA
GO:0055114
S4R3S4(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控ALDH2基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Alcoholic Intoxication, Chronic 0.470944373 141 3 BeFree_CLINVAR_CTD_human_GAD_GWASCAT
ALCOHOL SENSITIVITY, ACUTE 0.24 1 1 CLINVAR_CTD_human
Esophageal Neoplasms 0.214123245 60 1 BeFree_CTD_human_GAD_LHGDN
Malignant neoplasm of esophagus 0.175092902 54 1 BeFree_GAD_GWASCAT
Flushing 0.15743791 48 1 BeFree_CTD_human_GAD
Coronary heart disease 0.128729747 10 1 BeFree_GAD_GWASCAT
Colorectal Neoplasms 0.127815732 3 0 CTD_human_GAD_LHGDN
Asthma 0.126091273 6 0 BeFree_CTD_human_GAD
Squamous cell carcinoma of esophagus 0.125971721 22 4 BeFree_CTD_human
Precancerous Conditions 0.122367032 2 0 CTD_human_GAD
Cerebrovascular accident 0.121357209 6 2 BeFree_GWASCAT
Male infertility 0.12 1 0 CTD_human
Liver Cirrhosis, Experimental 0.12 1 0 CTD_human
Dermatitis, Occupational 0.12 1 0 CTD_human
Vascular Diseases 0.12 1 0 CTD_human
Ventricular Dysfunction 0.12 1 0 CTD_human
Complications of Diabetes Mellitus 0.12 1 0 CTD_human
Necrotizing Enterocolitis 0.12 1 0 CTD_human
HANGOVER, SUSCEPTIBILITY TO (finding) 0.12 0 1 CLINVAR
SUBLINGUAL NITROGLYCERIN, SUSCEPTIBILITY TO POOR RESPONSE TO 0.12 0 1 CLINVAR
Myocardial Ischemia 0.081085767 5 0 BeFree_RGD
Heart Diseases 0.080271442 2 0 BeFree_RGD
Fatty Liver, Alcoholic 0.08 1 0 RGD
Myocardial Reperfusion Injury 0.08 1 0 RGD
Drug-Induced Liver Injury 0.08 1 0 RGD
Squamous cell carcinoma 0.058042544 22 0 BeFree_GAD_LHGDN
Alcohol abuse 0.027666003 17 3 BeFree_GAD
Hypertensive disease 0.027013499 17 0 BeFree_GAD_LHGDN
Colorectal Cancer 0.024832032 16 3 BeFree_GAD
Alcoholic Liver Diseases 0.019912403 16 0 BeFree_GAD_LHGDN
Liver carcinoma 0.015264215 10 0 BeFree_GAD_LHGDN
Head and Neck Neoplasms 0.014202192 6 0 GAD
Malignant neoplasm of lung 0.012649486 5 0 BeFree_GAD
Esophageal carcinoma 0.012486326 46 1 BeFree
Myocardial Infarction 0.012268423 10 1 BeFree_GAD_LHGDN
Pancreatitis, Alcoholic 0.010825337 9 0 BeFree_GAD
Alzheimer's Disease 0.009825446 4 0 GAD_LHGDN
Liver Cirrhosis 0.009544073 10 0 BeFree_GAD
Laryngeal neoplasm 0.009468128 4 0 GAD
Mouth Neoplasms 0.009468128 4 0 GAD
Pharyngeal Neoplasms 0.009468128 4 0 GAD
Systemic arterial pressure 0.009468128 4 0 GAD
Liver diseases 0.008544182 7 0 BeFree_GAD_LHGDN
Malignant neoplasm of stomach 0.00853425 15 1 BeFree_GAD
Liver Cirrhosis, Alcoholic 0.008458305 7 0 BeFree_GAD
Diabetes Mellitus, Non-Insulin-Dependent 0.008186863 6 0 BeFree_GAD
Alcohol-Related Disorders 0.008186863 7 0 BeFree_GAD
Liver neoplasms 0.00764398 5 0 BeFree_GAD
Malignant neoplasm of breast 0.007372538 3 0 BeFree_GAD
Cancer of Head and Neck 0.007177041 10 4 BeFree_GAD
Coronary Artery Disease 0.007177041 9 1 BeFree_GAD
As If Personality 0.007101096 3 0 GAD
Pancreatitis 0.007101096 3 0 GAD
Diabetes Mellitus 0.006362715 6 3 BeFree_GAD
Pancreatitis, Chronic 0.00617715 5 0 BeFree_GAD_LHGDN
Alcoholic Intoxication 0.006091273 7 0 BeFree_GAD
Alcoholic Neuropathy 0.005634266 2 0 BeFree_GAD_LHGDN
Lung Neoplasms 0.0054487 2 0 LHGDN
Adenoma 0.005362824 1 0 BeFree_GAD_LHGDN
Atherosclerosis 0.005276948 3 0 BeFree_GAD
Periodontitis 0.005276948 2 0 BeFree_GAD
Diabetes Mellitus, Insulin-Dependent 0.005091382 2 0 GAD_LHGDN
Pancreatic Neoplasm 0.005091382 2 0 GAD_LHGDN
Cardiovascular Diseases 0.004810009 10 0 BeFree_GAD
Cocarcinogenesis 0.004734064 2 0 GAD
Colonic Neoplasms 0.004734064 2 0 GAD
DNA Damage 0.004734064 2 0 GAD
Oropharyngeal Neoplasms 0.004734064 2 0 GAD
Bone necrosis 0.004734064 2 0 GAD
Rectal Neoplasms 0.004734064 2 0 GAD
Cirrhosis 0.003995683 7 0 BeFree_GAD
heavy drinking 0.003800186 14 0 BeFree
Stomach Carcinoma 0.003800186 14 1 BeFree
Colorectal Carcinoma 0.003528744 13 3 BeFree
Melanosis 0.003181358 3 0 BeFree_GAD
Gastritis, Atrophic 0.002909916 3 0 BeFree_GAD
Chronic Obstructive Airway Disease 0.002909916 3 0 BeFree_GAD
Stomach Neoplasms 0.002638474 2 0 BeFree_GAD
Metabolic Syndrome X 0.002638474 1 0 BeFree_GAD
Coronary Arteriosclerosis 0.002442977 9 1 BeFree
Angina Pectoris 0.002367032 1 0 GAD
Malignant neoplasm of urinary bladder 0.002367032 1 0 GAD
Intracranial Aneurysm 0.002367032 1 1 GAD
Colonic Polyps 0.002367032 1 0 GAD
Digestive System Neoplasms 0.002367032 1 0 GAD
Drug Allergy 0.002367032 1 0 GAD
Ectodermal Dysplasia 0.002367032 1 0 GAD
Gastrointestinal Neoplasms 0.002367032 1 0 GAD
Hypersensitivity 0.002367032 1 0 GAD
Kidney Failure, Chronic 0.002367032 1 1 GAD
Mesothelioma 0.002367032 1 0 GAD
Metaplasia 0.002367032 1 0 GAD
Neoplasm Invasiveness 0.002367032 1 0 GAD
Neoplasm Metastasis 0.002367032 1 0 GAD
Obesity 0.002367032 1 0 GAD
Occupational Diseases 0.002367032 1 0 GAD
Parkinson Disease 0.002367032 1 0 GAD
Peptic Ulcer 0.002367032 1 0 GAD
Periodontal Pocket 0.002367032 1 0 GAD
Pleural Neoplasms 0.002367032 1 0 GAD
Retinopathy of Prematurity 0.002367032 1 0 GAD
Stomach Diseases 0.002367032 1 0 GAD
Substance Withdrawal Syndrome 0.002367032 1 0 GAD
Unconscious State 0.002367032 1 0 GAD
Helicobacter Infections 0.002367032 1 0 GAD
Neoplasms, Second Primary 0.002367032 1 0 GAD
Premature Birth 0.002367032 1 0 GAD
Adenomatous Polyps 0.002367032 1 0 GAD
Squamous Cell Neoplasms 0.002367032 1 0 GAD
Malignant neoplasm of prostate 0.002367032 1 0 GAD
Genomic Instability 0.002367032 1 0 GAD
Stroke, Lacunar 0.002367032 1 0 GAD
Carcinogenesis 0.002171535 8 1 BeFree
alcohol use disorder 0.001900093 7 0 BeFree
Diabetes 0.001357209 5 2 BeFree
Pancreatic carcinoma 0.001357209 5 0 BeFree
Malignant neoplasm of pancreas 0.001357209 5 0 BeFree
alcohol flush reaction 0.001357209 5 0 BeFree
Ischemia 0.001085767 4 0 BeFree
Essential Hypertension 0.001085767 4 1 BeFree
Macrocytosis 0.001085767 4 0 BeFree
Sensory Discomfort 0.001085767 4 0 BeFree
Hangover from alcohol 0.001085767 4 0 BeFree
Squamous cell carcinoma of the head and neck 0.001085767 4 3 BeFree
Antisocial Personality Disorder 0.000814326 3 0 BeFree
Anxiety Disorders 0.000814326 3 0 BeFree
Fanconi Anemia 0.000814326 3 0 BeFree
Fatty Liver 0.000814326 3 0 BeFree
Congestive heart failure 0.000814326 3 0 BeFree
Heroin Dependence 0.000814326 3 0 BeFree
Hangover from any Alcohol or Other Drugs substance 0.000814326 3 0 BeFree
Melanosis coli 0.000814326 3 0 BeFree
Malaise 0.000814326 3 0 BeFree
Antisocial behavior 0.000814326 3 0 BeFree
Multiple malignancy 0.000814326 3 0 BeFree
Acute alcoholic intoxication 0.000814326 3 0 BeFree
Alcohol problem 0.000814326 3 0 BeFree
Carcinoma of lung 0.000814326 3 0 BeFree
FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) 0.000814326 3 0 BeFree
Acute pancreatitis 0.000542884 2 0 BeFree
Arteriosclerosis 0.000542884 2 0 BeFree
Mental disorders 0.000542884 2 0 BeFree
Bipolar Disorder 0.000542884 2 0 BeFree
Rectal Carcinoma 0.000542884 2 0 BeFree
Cerebral Infarction 0.000542884 2 0 BeFree
Presenile dementia 0.000542884 2 0 BeFree
Congenital Heart Defects 0.000542884 2 0 BeFree
Heart failure 0.000542884 2 0 BeFree
Hyperglycemia 0.000542884 2 1 BeFree
Nicotine Dependence 0.000542884 2 6 BeFree
Pancytopenia 0.000542884 2 0 BeFree
Psychotic Disorders 0.000542884 2 0 BeFree
Conduct Disorder 0.000542884 2 0 BeFree
Acute myocardial infarction 0.000542884 2 0 BeFree
Bipolar II disorder 0.000542884 2 0 BeFree
Alcohol or Other Drugs use 0.000542884 2 0 BeFree
Impaired glucose tolerance 0.000542884 2 2 BeFree
Proliferative retinopathy 0.000542884 2 0 BeFree
Neuropathy 0.000542884 2 0 BeFree
Dementia 0.000542884 2 0 BeFree
Carotid Atherosclerosis 0.000542884 2 0 BeFree
Adenoma of large intestine 0.000542884 2 0 BeFree
Steatohepatitis 0.000542884 2 0 BeFree
Adenocarcinoma 0.000271442 1 0 BeFree
Airway Obstruction 0.000271442 1 0 BeFree
Alcohol Withdrawal Delirium 0.000271442 1 0 BeFree
Anemia, Macrocytic 0.000271442 1 0 BeFree
Autistic Disorder 0.000271442 1 0 BeFree
Female Breast Carcinoma 0.000271442 1 0 BeFree
Carcinoma, Transitional Cell 0.000271442 1 0 BeFree
Cardiomyopathy, Alcoholic 0.000271442 1 0 BeFree
Cardiomyopathy, Dilated 0.000271442 1 0 BeFree
Cyanosis 0.000271442 1 0 BeFree
Dehydration 0.000271442 1 0 BeFree
Mental Depression 0.000271442 1 0 BeFree
Depressive disorder 0.000271442 1 0 BeFree
Diabetic Nephropathy 0.000271442 1 0 BeFree
Diabetic Retinopathy 0.000271442 1 0 BeFree
Duodenal Ulcer 0.000271442 1 0 BeFree
Epilepsy 0.000271442 1 1 BeFree
Gingival Diseases 0.000271442 1 0 BeFree
Hyperinsulinism 0.000271442 1 0 BeFree
Muscular Atrophy 0.000271442 1 0 BeFree
Nausea 0.000271442 1 0 BeFree
Osteoporosis 0.000271442 1 0 BeFree
Pancreatic Pseudocyst 0.000271442 1 0 BeFree
Periodontal Diseases 0.000271442 1 0 BeFree
polyps 0.000271442 1 0 BeFree
Retinal Diseases 0.000271442 1 0 BeFree
Schizophrenia 0.000271442 1 0 BeFree
Tetralogy of Fallot 0.000271442 1 0 BeFree
Erythema 0.000271442 1 0 BeFree
Viral hepatitis 0.000271442 1 0 BeFree
Photophobia 0.000271442 1 0 BeFree
Oral Cavity Carcinoma 0.000271442 1 0 BeFree
Congenital heart disease 0.000271442 1 0 BeFree
Polyneuropathy 0.000271442 1 0 BeFree
Malignant neoplasm of mouth 0.000271442 1 0 BeFree
Malignant neoplasm of pharynx 0.000271442 1 0 BeFree
Malignant neoplasm of female breast 0.000271442 1 0 BeFree
Fibrosis, Liver 0.000271442 1 0 BeFree
Dyslipidemias 0.000271442 1 1 BeFree
Cyanotic congenital heart disease 0.000271442 1 0 BeFree
Impaired cognition 0.000271442 1 0 BeFree
Chronic liver disease 0.000271442 1 0 BeFree
Malignant neoplasm of liver 0.000271442 1 1 BeFree
Wernicke-Korsakoff Syndrome 0.000271442 1 0 BeFree
Multiple lacunar infarcts 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
hazardous drinking 0.000271442 1 0 BeFree
Malignant neoplasm of gastrointestinal tract 0.000271442 1 0 BeFree
Hyperuricemia 0.000271442 1 0 BeFree
Cardiac defects 0.000271442 1 0 BeFree
Pharyngeal Carcinoma 0.000271442 1 0 BeFree
Mitochondrial Diseases 0.000271442 1 0 BeFree
Helicobacter pylori infection 0.000271442 1 0 BeFree
Bipolar I disorder 0.000271442 1 0 BeFree
Cardiomyopathies 0.000271442 1 0 BeFree
Cerebral Ischemia 0.000271442 1 0 BeFree
Acute Coronary Syndrome 0.000271442 1 0 BeFree
Polyp of large intestine 0.000271442 1 0 BeFree
Primary Carcinoma 0.000271442 1 0 BeFree
Hepatocarcinogenesis 0.000271442 1 0 BeFree
ST segment elevation myocardial infarction 0.000271442 1 0 BeFree
CHLORPROPAMIDE-ALCOHOL FLUSHING 0.000271442 1 0 BeFree
Urothelial Carcinoma 0.000271442 1 0 BeFree
Chronic Total Occlusion Vessel 0.000271442 1 0 BeFree
Alcohol abuse or dependence 0.000271442 1 0 BeFree
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