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ACP2

Gene name:acid phosphatase 2, lysosomal

...ACP2缺陷相关,表现为胆固醇代谢异常和神经系统损伤。此外,ACP2表达异常还与某些癌症(如前列腺癌、乳腺癌)的进展相关,可能通过影响细胞凋亡或增殖信号通路发挥作用。若ACP2过表达,可能加剧溶酶体功能紊乱,导致细胞毒性或异常自噬;而表达降...

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