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The retinoblastoma gene is targeted for rearrangements in BRCA1-deficient basal…

样本量:1154 物种:Homo sapiens 类型:transcription profiling by array June 26, 2012

...BRCA1/2 mutation carriers. Focusing on the RB1 locus, we analyzed 33 BRCA1-mutated, 36 BRCA2-mutated and 48 non-BRCA1/2-...

Integration of BRCA1-mediated miRNA and mRNA signatures reveal miR-146a, miR-99…

样本量:12 物种:Homo sapiens 类型:transcription profiling by array Dec. 24, 2011

...BRCA1-associated tumorigenesis are still largely unknown. In order to deepen our understanding of BRCA1-associated tumor...

Expression data from mammary epithelial cells from BRCA1 mutation carriers and …

样本量:14 物种:Homo sapiens 类型:transcription profiling by array Nov. 19, 2008

...BRCA1-related tumors, and that the EGFR pathway is upregulated in BRCA1 mutation carriers compared ton non BRCA1 mutatio...

BRCT phosphoprotein recognition, but not E3 ligase activity, is essential for B…

样本量:6 物种:Mus musculus 类型:comparative genomic hybridization by ar… Aug. 25, 2011

...BRCA1, in the form of the BRCA1/BARD1 heterodimer, acting as an ubiquitin E3 ligase offered a possible mechanism to expl...

Normal human mammary tissues from BRCA1 mutation carriers, non-BRCA1/2 mutation…

样本量:20 物种:Homo sapiens 类型:transcription profiling by array Aug. 1, 2009

...BRCA1 (n=7) and non-BRCA1/2 mutation carriers (n=8). non-BRCA1/2 carriers were individuals with a strong family history ...

Genome-wide analysis of RNAs translationally regulated upon BRCA1 depletion in …

样本量:8 物种:Homo sapiens 类型:transcription profiling by array Dec. 31, 2013

...BRCA1-depleted cells and increased in BRCA1-overexpressing cells. Our findings raised the question whether BRCA1 affects...

Effect of BRCA1 heterozygous mutation on gene expression

样本量:21 物种:Homo sapiens 类型:transcription profiling by array Dec. 31, 2015

...BRCA1, 5 LCLs carrying missense mutation in BRCA1, and 10 LCLs harboring truncating mutation in BRCA1 were included in t...

miRNA expression in healthy carriers of heterozygous BRCA1 mutation and healthy…

样本量:21 物种:Homo sapiens 类型:transcription profiling by array Dec. 31, 2015

...BRCA1, 5 LCLs carrying missense mutation in BRCA1, and 10 LCLs harboring truncating mutation in BRCA1 were included in t...

Tumor Suppressor BRCA1 epigenetically controls oncogenic miRNA-155

样本量:15 物种:Mus musculus 类型:transcription profiling by array Dec. 31, 2011

...BRCA1, miR-155 is up-regulated in BRCA1-deficient mouse mammary epithelial cells, human and mouse BRCA1-deficienct breas...

DNA methylation profiling of whole blood DNA samples from BRCA1 wild-types with…

样本量:84 物种:Homo sapiens 类型:methylation profiling by array May 6, 2014

...BRCA1 mutation status represent 0=healthy-brca1wt, 1=healthy-brca1mt, 2=breastcancer-brca1mt.

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