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Knock-in of PIK3CA-H1047R into MCF-10A

样本量:25 物种:Homo sapiens 类型:RNA-seq of coding RNA 2015年1月19日

...PIK3CA gene which encodes the catalytic subunit p110α of phosphatidylinositol 3-kinase (PI3K). The H1047R mutation of PI...

mRNA expression data from adenoma, gene modified, and colorectal cancer organoid

样本量:23 物种:Homo sapiens 类型:transcription profiling by array 2015年1月18日

...PIK3CA E545K knock in. 2) Genome-engineered organoids with Lent virus vector B = CTNNB1 S33Y overexpression; K = KRAS G1...

Gene expression profiling of myxoid liposarcomas (validation set INT-B)

样本量:12 物种:Homo sapiens 类型:transcription profiling by array 2014年10月30日

...PIK3CA and PTEN mutations and growth factor receptor signalling such as RET and IGF1R have been recently correlated with...

Gene expression profiling of myxoid liposarcomas (training set INT-A)

样本量:12 物种:Homo sapiens 类型:transcription profiling by array 2014年10月30日

...PIK3CA and PTEN mutations and growth factor receptor signalling such as RET and IGF1R have been recently correlated wit...

Potent antitumor activity of Cabozantinib, a c-MET and VEGFR2 Inhibitor, in a...

样本量:6 物种:Homo sapiens 类型:RNA-seq of coding RNA 2014年8月30日

...PIK3CA gene. The underlying antitumor mechanisms of cabozantinib consisted of inhibition of angiogenesis and Akt activat...

Sporadic early-onset colorectal carcinoma is a distinct clinicopathological a...

样本量:70 物种:Homo sapiens 类型:transcription profiling by array 2014年8月4日

...PIK3CA) were detected and the methylator phenotype (CIMP) established. Gene expression profiles (GEP) were obtained usin...

Transcriptional data from yeast expressing mammalian PIK3CA

样本量:6 物种:Saccharomyces cerevisiae 类型:transcription profiling by array 2014年7月19日

We studied the transcriptional profile in response to acute PtdIns-4,5P2 depletion induced by heterologous expression of...

Gene expression profiles of PIK3CA knockdown by shRNA in lung cancer cells

样本量:6 物种:Mus musculus 类型:transcription profiling by array 2014年5月2日

...PIK3CA shRNA, in 344SQ lung cancer cell line Two group comparison

Gene expression profiling upon PI3K inhibition using different inhibitors

样本量:12 物种:Homo sapiens 类型:transcription profiling by array 2014年4月8日

...PIK3CA (E545K)-mutated MCF7 breast cancer cells. Treatment with ETP-45658 or PI-103 resulted in a time and concentration...

Understanding molecular mechanisms of Cetuximab insensitivity in Colorectal C...

样本量:8 物种:Homo sapiens 类型:transcription profiling by array 2014年4月1日

...PIK3CA) and expression (AREG/EREG) analysis of key genes, transcriptomic profiling and GSEA were carried out to elucidat...

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