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Molecular Landscape of Resected Thymomas: Insights from Mutational Profiling.

Frasca(L),Sarubbi(A),Nibid(L),Suriano(I),L... Diagnostics (Basel) 2026-02-05

...PIK3CA mutation; no other targetable mutations were observed. Moreover, high PD-L1 expression (≥50%) was reported in (15...

Endometrial Mixed and Mixed-Feature Carcinomas: Small Cohort Clinicopathologi...

Bhardwaj(S),Saleh(M),Kinoshita(Y),Brody(R)... Cancers (Basel) 2026-01-29

...PIK3CA, TERT, MAP2K1 genes, and ERBB2 gene amplifications, were assessed and compared to pure serous and pure endometrio...

Comparison Between Alpelisib Plus Endocrine Therapy and Everolimus Plus Endoc...

Loizidis(S),Michaelides(D),Marcou(Y),Kakou... Cancers (Basel) 2026-01-30

...PIK3CA mutations (PIK3CA-wild-type group) and received everolimus as a subsequent treatment after progression on CDK4/6i...

Synergistic Mechanistic Insights into Anti-T2DM Benefits of Lentinula edodes:...

Ma(HK),Meng(L),Shen(L),Ji(HF) Foods 2026-01-27

...PIK3CA, and PIK3R1. Third, pathway enrichment analysis showed that these core targets were significantly enriched within...

Extracellular vesicles from human adipose-derived stem cells relieve pain and...

Kim(WS),Woo(CH),Lee(KS),Choi(YC),Yun(YE),C... Stem Cell Res Ther 2026-02-13

...PIK3CA and AKT1. In vivo, hASC-EV treatment markedly improved PWL, PWT, and weight-bearing performance compared with unt...

Genetic Syndromes Associated With Congenital Upper Limb Differences.

Elsherbini(A),Perlmutter(J),Mosa(A) J Hand Surg Am 2026-05-00

...PIK3CA, AKT1, and RASA1) linked to overgrowth syndromes (eg, congenital lipomatous overgrowth, vascular differences, epi...

Beyond EGFR inhibition in head and neck squamous cell carcinoma: Overcoming r...

Carosi(F),Filippini(DM),Fabbri(L),Carlini(... Crit Rev Oncol Hematol 2026-05-00

...PIK3CA mutations, PTEN loss), epithelial-mesenchymal transition (EMT), and immunosuppressive tumor microenvironment fact...

Emerging role of DNA polymerase epsilon non-exonuclease domain mutations in c...

Xu(JJ),Ni(CX),Xu(JJ) World J Gastroenterol 2026-02-14

...PIK3CA, and BRAF, implying a potential synergistic interaction between impaired DNA repair mechanisms and activation of ...

Potential cardioprotective and regenerative effects of the fluorinated benzot...

Dharshan(SS),Rao(SM),Ranjan Nayak(SPR),Ram... Biochimie 2026-06-00

...PIK3CA). Behavioural Assays determined that AS09 significantly improved anxiety and increased locomotion. Biochemical as...

Integrated network toxicology, transcriptomics and metabolomics to elucidate ...

Du(JY),Ren(YF),Ni(BH),Li(JL),Wang(CC),Li(X... Environ Int 2026-03-00

...PIK3CA with DEHP metabolite mono(2-ethylhexyl) phthalate (MEHP) stably binding them via docking. Integrated analysis of ...

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