样本量：30 物种：Homo sapiens 类型：DNA-seq 2018年12月13日

...CRISPR/Cas9 activity and the induced indel profiles. We used two different doses of Trichostatin and two different doses...

样本量：14 物种：Bacillus halodurans, Escherichia coli... 类型：other 2016年2月17日

...CRISPR-Cas systems: E. coli I-E, B. halodurans I-C, S. thermophilus CR1 II-A, and F. novicida V. Cells containing functi...

样本量：54 物种：Homo sapiens 类型：ATAC-seq 2017年2月28日

...CRISPR/Cas9 and 100 gRNAs targeting mtDNA. The other was the removal of detergent from the cell lysis step. There are 27...

样本量：4 物种：Homo sapiens 类型：genotyping by high throughput sequencing 2020年1月19日

...CRISPR library (GeCKOv2, Addgene #1000000049) and subjected to hepatitis A virus infection (HM175/18f) to isolate virus-...

样本量：3 物种：Mus musculus 类型：RNA-seq of coding RNA 2015年10月26日

PolyA+ RNA-Seq was performed on wildtype, ATRX and DAXX knockout cells derived by CRISPR targeting (Sadic et. al, EMBO R...

样本量：6 物种：Homo sapiens 类型：RNA-seq of coding RNA, RNA-seq of non... 2016年7月1日

The functional relevance of many microRNAs in the context of tumor biology remains unclear. Using CRISPR-Cas9 technology...

样本量：3 物种：Homo sapiens 类型：transcription profiling by array 2013年8月10日

...CRISPR-on system, a two-component transcriptional activator consisting of a nuclease-dead Cas9 (dCas9) protein fused wit...

样本量：12 物种：Mus musculus 类型：RNA-seq of coding RNA 2019年7月9日

...CRISPR activation. Cells were first stably transfected with the lenti-MS2-p65-HSF1 activator plasmid. Respective sgRNAs ...

样本量：5 物种：Homo sapiens 类型：RNA-seq of coding RNA 2016年6月1日

...CRISPR-dCas9 DNA methyltransferases to mediate targeted DNA methylation. Using the dCas9-BFP-DNMT3A and dCas9-BFP-DNMT3B...

样本量：15 物种：Homo sapiens 类型：ChIP-seq 2015年4月24日

...CRISPR- and TALE-based genome engineering tools. We have analyzed the genome-wide effects of TALE- and CRISPR-based tran...